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上海药物研究所 [18]
重庆大学 [2]
山东大学 [2]
上海中医药大学 [2]
北京大学 [1]
西北高原生物研究所 [1]
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期刊论文 [29]
学位论文 [1]
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Functional Proliferating Human Hepatocytes: In Vitro Hepatocyte Model for Drug Metabolism, Excretion, and Toxicity
期刊论文
DRUG METABOLISM AND DISPOSITION, 2021, 卷号: 49, 期号: 4, 页码: 305-313
作者:
Qiao, Shida
;
Feng, Sisi
;
Wu, Zhitao
;
He, Ting
;
Ma, Chen
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2021/05/24
HgS and Zuotai differ from HgCl2 and methyl mercury in intestinal Hg absorption, transporter expression and gut microbiome in mice
期刊论文
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2019, 卷号: 379
作者:
Zhang, Bin-Bin
;
Liu, Yong-Mei
;
Hu, An-Ling
;
Xu, Shang-Fu
;
Fan, Li-Da
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  |  
浏览/下载:72/0
  |  
提交时间:2019/11/26
HgS
Zuotai
HgCl2
MeHg
Gut microbiome
Gut transporter
Intestinal Transporter-Associated Drug Absorption and Toxicity
期刊论文
DRUG TRANSPORTERS IN DRUG DISPOSITION, EFFECTS AND TOXICITY, 2019, 卷号: 1141, 页码: 361-405
作者:
Xue, Yaru
;
Ma, Chenhui
;
Hanna, Imad
;
Pan, Guoyu
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2020/07/01
Intestinal transporter
Drug absorption
Bile acid transport
BDDCS
Drug-induced toxicity
18β-Glycyrrhetinic acid protects against alpha-naphthylisothiocyanate-induced cholestasis through activation of the Sirt1/FXR signaling pathway
期刊论文
Acta pharmacologica Sinica, 2018, 卷号: 39, 期号: 12, 页码: 1865-1873
作者:
Wu, Shou-Yan
;
Cui, Shi-Chao
;
Wang, Le
;
Zhang, Yi-Ting
;
Yan, Xiao-Xia
收藏
  |  
浏览/下载:96/0
  |  
提交时间:2019/01/08
18 beta-Glycyrrhetinic acid protects against alpha-naphthylisothiocyanate-induced cholestasis through activation of the Sirt1/FXR signaling pathway
期刊论文
ACTA PHARMACOLOGICA SINICA, 2018, 卷号: 39, 期号: 12, 页码: 1865-1873
作者:
Wu, Shou-yan
;
Cui, Shi-chao
;
Wang, Le
;
Zhang, Yi-ying
;
Yan, Xiao-xia
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2020/07/01
hepatoprotective effect
cholestatic liver injury
18 beta-glycyrrhetinic acid (18b-GA)
FXR
Sirt1
bile acid transporters
Glycyrrhizin has a high likelihood to be a victim of drug-drug interactions mediated by hepatic organic anion-transporting polypeptide 1B1/1B3
期刊论文
BRITISH JOURNAL OF PHARMACOLOGY, 2018, 卷号: 175, 期号: 17, 页码: 3486-3503
作者:
Dong, Jiajia
;
Olaleye, Olajide E.
;
Jiang, Rongrong
;
Li, Jing
;
Lu, Chuang
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  |  
浏览/下载:104/0
  |  
提交时间:2019/01/08
Leflunomide Increases Hepatic Exposure to Methotrexate and Its Metabolite by Differentially Regulating Multidrug Resistance-Associated Protein Mrp2/3/4 Transporters via Peroxisome Proliferator-Activated Receptor alpha Activation
期刊论文
MOLECULAR PHARMACOLOGY, 2018, 卷号: 93, 期号: 6, 页码: 563-574
作者:
Wang, Le
;
Ma, Leilei
;
Lin, Yunfei
;
Liu, Xing
;
Xiao, Ling
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  |  
浏览/下载:52/0
  |  
提交时间:2019/01/08
Dysregulated bile acid signaling contributes to the neurological impairment in murine models of acute and chronic liver failure
期刊论文
EBIOMEDICINE, 2018, 卷号: 37
作者:
Xie, Guoxiang
;
Wang, Xiaoning
;
Jiang, Runqiu
;
Zhao, Aihua
;
Yan, Jingyu
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  |  
浏览/下载:16/0
  |  
提交时间:2019/12/05
Bile acids
Ammonia
Hepatic encephalopathy
Apical sodium-dependent bile acid transporter
Mechanisms of Triptolide-Induced Hepatotoxicity and Protective Effect of Combined Use of Isoliquiritigenin: Possible Roles of Nrf2 and Hepatic Transporters
期刊论文
Frontiers in Pharmacology, 2018, 卷号: Vol.9
作者:
Hou, ZY
;
Chen, L
;
Fang, PF
;
Cai, HL
;
Tang, HB
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/26
triptolide
hepatotoxicity
isoliquiritigenin
nuclear
transcription
factor
E2-related
factor
2
transporter
bile
acid
Mechanisms of Triptolide-Induced Hepatotoxicity and Protective Effect of Combined Use of Isoliquiritigenin: Possible Roles of Nrf2 and Hepatic Transporters.
期刊论文
Frontiers in pharmacology, 2018, 卷号: 9, 期号: MAR, 页码: 226
作者:
Hou, Zhenyan
;
Chen, Lei
;
Fang, Pingfei
;
Cai, Hualin
;
Tang, Huaibo
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2019/12/27
bile acid
hepatotoxicity
isoliquiritigenin
nuclear transcription factor E2-related factor 2
transporter
triptolide
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