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上海药物研究所 [3]
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北京大学 [1]
中国医学科学院 北京... [1]
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期刊论文 [7]
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2016 [4]
2015 [1]
2014 [1]
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Application of electrophysiological technique in toxicological study: From manual to automated patch-clamp recording
期刊论文
TRAC-TRENDS IN ANALYTICAL CHEMISTRY, 2020, 卷号: 133, 页码: 1-9
作者:
Gao, Jia
;
Zhang, He
;
Xiong, Ping
;
Yan, Xueting
;
Liao, Chunyang
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2021/09/14
Manual patch-clamp
Automated patch-clamp
Ion channel characterization
High throughput screening
Toxicity
Cardiotoxicity screening: a review of rapid-throughput in vitro approaches
期刊论文
ARCHIVES OF TOXICOLOGY, 2016, 卷号: 90, 期号: 8, 页码: 1803-1816
作者:
Li, Xichun
;
Zhang, Rui
;
Zhao, Bin
;
Lossin, Christoph
;
Cao, Zhengyu
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2017/03/27
Cardiotoxicity
Rapid throughput
hERG
Automated patch clamp
Microelectrode array
Fluorescence plate reader
Investigation of miscellaneous hERG inhibition in large diverse compound collection using automated patch-clamp assay
期刊论文
2016, 卷号: 37, 期号: 1, 页码: 111-123
作者:
Hai-bo YU
;
Bei-yan ZOU
;
Xiao-liang WANG
;
Min LI
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2020/01/04
hERG
high-throughput screening
MLSMR library
automated electrophysiology
cardiotoxicity
Novel KCNQ2 channel activators discovered using fluorescence-based and automated patch-clamp-based high-throughput screening techniques
期刊论文
ACTA PHARMACOLOGICA SINICA, 2016, 卷号: 37, 期号: 1, 页码: 105-110
作者:
Yue, Jin-feng
;
Qiao, Guan-hua
;
Liu, Ni
;
Chen, Xue-qin
;
Nan, Fa-jun
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2019/01/08
KCNQ2
channel activator
high-throughput screening
thallium flux assay
automated patch-clamp
ZG1732
ZG2083
Novel KCNQ2 channel activators discovered using fluorescence-based and automated patch-clampbased high-throughput screening techniques
期刊论文
Acta Pharmacologica Sinica, 2016, 卷号: 37, 期号: 1, 页码: 105
作者:
Yue Jinfeng
;
Qiao Guanhua
;
Liu Ni
;
Chen Xueqin
;
Nan Fajun
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2020/07/01
POTASSIUM CHANNEL
KV7 CHANNELS
EPILEPSY
IDENTIFICATION
GENE
KCNQ2
channel activator
high-throughput screening
thallium flux assay
automated patch-clamp
ZG1732
ZG2083
Development of Automated Patch Clamp Assay for Evaluation of α7 Nicotinic Acetylcholine Receptor Agonists in Automated QPatch-16
期刊论文
2015
Hao Yuchen
;
Tang Jingshu
;
Wang KeWei
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2015/11/13
Design, Synthesis, and Structure-Activity Relationship Studies of Novel Fused Heterocycles-Linked Triazoles with Good Activity and Water Solubility
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2014, 卷号: 57, 期号: 9, 页码: 3687-3706
作者:
Cao, Xufeng
;
Sun, Zhaoshuan
;
Cao, Yongbing
;
Wang, Ruilian
;
Cai, Tongkai
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  |  
浏览/下载:14/0
  |  
提交时间:2019/01/08
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