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海洋研究所 [5]
上海药物研究所 [4]
昆明植物研究所 [3]
山东大学 [3]
南海海洋研究所 [2]
四川大学 [2]
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期刊论文 [29]
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Novel tetrahydrobenzo[b]thiophen-2-yl)urea derivatives as novel alpha-glucosidase inhibitors: Synthesis, kinetics study, molecular docking, and in vivo anti-hyperglycemic evaluation
期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 115, 页码: 17
作者:
Xie, Hong-Xu
;
Zhang, Juan
;
Li, Yue
;
Zhang, Jin-He
;
Liu, Shan-Kui
收藏
  |  
浏览/下载:69/0
  |  
提交时间:2021/11/04
Tetrahydrobenzo[b]thiophen-2-yl)urea
alpha-Glucosidase inhibitors
Non-competitive inhibitor
Molecular docking
Anti-hyperglycaemic activity
Type 2 diabetes
SL010110, a lead compound, inhibits gluconeogenesis via SIRT2-p300-mediated PEPCK1 degradation and improves glucose homeostasis in diabetic mice
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 13
作者:
Ren, Yu-ran
;
Ye, Yang-liang
;
Feng, Ying
;
Xu, Ti-fei
;
Shen, Yu
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2021/05/24
SL010110
gluconeogenesis
primary mouse hepatocytes
PEPCK1
acetylation
degradation
Curcumin-loaded liposomes prepared from bovine milk and krill phospholipids: Effects of chemical composition on storage stability, in-vitro digestibility and anti-hyperglycemic properties
期刊论文
FOOD RESEARCH INTERNATIONAL, 2020, 卷号: 136
作者:
Wu, Yujie
;
Mou, Bolin
;
Song, Shuang
;
Tan, Chin-Ping
;
Lai, Oi-Ming
收藏
  |  
浏览/下载:58/0
  |  
提交时间:2020/12/16
PHYSICOCHEMICAL PROPERTIES
CHITOSAN
TEMPERATURE
OIL
PH
BIOACCESSIBILITY
BIOAVAILABILITY
EXTRACTS
Design, synthesis and biological evaluation of novel pyrimidinedione derivatives as DPP-4 inhibitors
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2018, 卷号: 28, 期号: 12, 页码: 2131-2135
作者:
Li, Ning
;
Wang, Li-Jun
;
Jiang, Bo
;
Guo, Shu-Ju
;
Li, Xiang-Qian
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  |  
浏览/下载:58/0
  |  
提交时间:2019/08/21
Pyrimidinedionederivatives
DPP-4 inhibitor
Molecular hybrid
SARs
Type 2 diabetes
Erythritol Attenuates Postprandial Blood Glucose by Inhibiting alpha-Glucosidase
期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2018, 卷号: 66, 期号: 6
作者:
Wen, Huaixiu
;
Tang, Bowen
;
Stewart, Alan J.
;
Tao, Yanduo
;
Shao, Yun
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2019/11/26
diabetes mellitus
postprandial blood glucose
erythritol
alpha-glucosidase
competitive inhibition
Evaluation of the Anti-Diabetic Activity of Polysaccharide from Cordyceps cicadae in Experimental Diabetic Rats
期刊论文
CHEMISTRY & BIODIVERSITY, 2018, 卷号: 15, 期号: 8, 页码: e1800219
作者:
Zhang, Qianping[1]
;
Olatunji, Opeyemi J.[2]
;
Chen, Hongxia[3]
;
Tola, Adesola J.[4]
;
Oluwaniyi, Omolara O.[5]
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2019/12/24
Cordyceps cicadae
anti-hyperglycemic activity
polysaccharide
diabetes
Novel benzamido derivatives as PTP1B inhibitors with anti-hyperglycemic and lipid-lowering efficacy
期刊论文
2018, 卷号: 8, 期号: 6, 页码: 919-932
作者:
Tang, Yanbo
;
Zhang, Xiaolin
;
Chen, Zheng
;
Yin, Wenwen
;
Nan, Guanglei
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2020/01/03
PTP1B inhibitors
Benzarnido derivatives
Structureactivity relationship
Anti-hyperglycemic
Lipid-lowering
Exploring the molecular basis of adaptive evolution in hydrothermal vent crab Austinograea alayseae by transcriptome analysis
期刊论文
PLOS ONE, 2017, 卷号: 12, 期号: 5
作者:
Hui, Min
;
Song, Chengwen
;
Liu, Yuan
;
Li, Chaolun
;
Cui, Zhaoxia
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2017/09/30
Gigantol from Dendrobium chrysotoxum Lindl. binds and inhibits aldose reductase gene to exert its anti-cataract activity: An in vitro mechanistic study
期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2017, 卷号: 198, 页码: 255-261
作者:
Wu,Jie
;
li,Xue
;
Wan,Wencheng
;
Yang,Qiaohong
;
Ma,Weifeng
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2017/10/23
Enhanced Raman-scattering
Calf Thymus Dna
Diabetic Complications
Cataract
Rats
Projections
Progression
Prevalence
Blindness
Cells
Gigantol
Aldose Reductase (Ar) Gene
Interaction
Uv-visible Spectroscopy
Atomic Force Microscopy (Afm)
Surface-enhanced Raman Spectroscopy (Sers)
Formononetin exhibits anti-hyperglycemic activity in alloxan-induced type 1 diabetic mice
期刊论文
EXPERIMENTAL BIOLOGY AND MEDICINE, 2017, 卷号: 242, 期号: 2, 页码: 223-230
作者:
Qiu, Guizhen
;
Tian, Wei
;
Huan, Mei
;
Chen, Jinlong
;
Fu, Haitao
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/11
Formononetin
type 1 diabetes
anti-hyperglycemic activity
islet B cell
apoptosis and regeneration
insulin secretion
glycolysis
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