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上海药物研究所 [2]
武汉物理与数学研究所 [2]
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期刊论文 [11]
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Interplay between Alzheimer's disease and global glucose metabolism revealed by the metabolic profile alterations of pancreatic tissue and serum in APP/PS1 transgenic mice
期刊论文
ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 10, 页码: 1259-1268
作者:
Liu, Xia
;
Wang, Wei
;
Chen, Hua-li
;
Zhang, Hai-yan
;
Zhang, Nai-xia
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2020/07/01
Alzheimer's disease
type 2 diabetes
APP/PS1 transgenic mice
metabolomics
NMR
glucose metabolism dysfunctions
Naringin Dihydrochalcone Ameliorates Cognitive Deficits and Neuropathology in APP/PS1 Transgenic Mice
期刊论文
FRONTIERS IN AGING NEUROSCIENCE, 2018, 卷号: 10, 期号: 1, 页码: -
作者:
Yang, Wenjuan
;
Zhou, Keyan
;
Zhou, Yue
;
An, Yuqian
;
Hu, Tingting
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2019/04/28
Adult Hippocampal Neurogenesis
A-beta Levels
Alzheimers-disease
Vitamin-e
Amyloid Deposition
Mouse Model
Curcumin
Memory
Trial
Neuroinflammation
Fluoxetine administration during adolescence attenuates cognitive and synaptic deficits in adult 3 x TgAD mice
期刊论文
NEUROPHARMACOLOGY, 2017, 卷号: 126, 页码: 200-212
作者:
Ke, Dan
;
Sun, Dong-Sheng
;
Gao, Li-Feng
;
Jin, Li
;
Wu, Hao
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2017/12/26
Fluoxetine
Alzheimer's Disease
Cognitive
Mri
Bdnf
GENDER DIFFERENCES OF PERIPHERAL PLASMA AND LIVER METABOLIC PROFILING IN APP/PS1 TRANSGENIC AD MICE
期刊论文
NEUROSCIENCE, 2016, 卷号: 332, 页码: 160-169
作者:
Wu, Junfang
;
Fu, Bin
;
Lei, Hehua
;
Tang, Huiru
;
Wang, Yulan
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2016/11/04
Alzheimer's disease
gender difference
metabonomics
peripheral
liver extracts
fatty acids
Donepezil attenuates A beta-associated mitochondrial dysfunction and reduces mitochondrial A beta accumulation in vivo and in vitro
期刊论文
NEUROPHARMACOLOGY, 2015, 卷号: 95, 页码: 29-36
作者:
Ye, Chun Yan
;
Lei, Yun
;
Tang, Xi Can
;
Zhang, Hai Yan
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2019/01/08
Alzheimer's disease
Donepezil
Amyloid-beta
Oligomer
Mitochondrial dysfunction
Quantitative proteomics reveals that PEA15 regulates astroglial A beta phagocytosis in an Alzheimer's disease mouse model
期刊论文
journal of proteomics, 2014
Lv, Junniao
;
Ma, Shuaipeng
;
Zhang, Xuefei
;
Zheng, Liangjun
;
Ma, Yuanhui
;
Zhao, Xuyang
;
Lai, Wenjia
;
Shen, Hongyan
;
Wang, Qingsong
;
Ji, Jianguo
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2015/11/10
Quantitative proteomics
PEA15
A beta
Phagocytosis
Alzheimer&apos
APP/PS1 mouse
MIGRATION INHIBITORY FACTOR
AMYLOID-BETA
GLUTAMINE-SYNTHETASE
ASTROCYTE MIGRATION
GLIOMA-CELLS
IN-VITRO
PROTEIN
CLEARANCE
PEA-15
EXPRESSION
s disease
Neural Stem Cell Transplants Improve Cognitive Function Without Altering Amyloid Pathology in an APP/PS1 Double Transgenic Model of Alzheimer's Disease
期刊论文
MOLECULAR NEUROBIOLOGY, 2014, 卷号: 50, 期号: 2
作者:
Zhang, Wei
;
Wang, Pei-Jun
;
Sha, Hong-ying
;
Ni, Jiong
;
Li, Ming-hua
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/19
Neural stem cells (NSCs)
Neuron
Oligodendrocytes
Astrocyte
Transplantation
Alzheimer's disease (AD)
APP/PS1 transgenic mouse
NMDA
Synaptophysin
PKC zeta
TrkB
BDNF
LTP
Cognition
Amyloid
Serum beta-Amyloid Peptide Levels Spike in the Early Stage of Alzheimer-Like Plaque Pathology in an APP/PS1 Double Transgenic Mouse Model
期刊论文
CURRENT ALZHEIMER RESEARCH, 2013, 卷号: 10, 期号: 9, 页码: 979-986
作者:
He, Jue[1]
;
Qiao, Jin-Ping[2]
;
Zhu, Shenghua[3]
;
Xue, Mengzhou[4]
;
Chen, Wenwu[5]
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/23
APP/PS1 double transgenic mouse model
serum
beta-amyloid
Alzheimer's disease
plaque
memory
Calpain Activation Promotes BACE1 Expression, Amyloid Precursor Protein Processing, and Amyloid Plaque Formation in a Transgenic Mouse Model of Alzheimer Disease
期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2010, 卷号: 285, 期号: 36, 页码: 27737-27744
作者:
Luo, Zhen-Ge
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2012/07/13
BETA-SECRETASE ACTIVITY
IN-VIVO
BRAIN-INJURY
WATER-MAZE
MICE
PRESENILIN-1
NEURODEGENERATION
DEPOSITION
CALCIUM
P25
Increased Hippocampal Neurogenesis in the Progressive Stage of Alzheimer's Disease Phenotype in an APP/PS1 Double Transgenic Mouse Model
期刊论文
HIPPOCAMPUS, 2009, 卷号: 19, 期号: 12
作者:
Luo, Huanmin
;
Yu, Yingxin
;
He, Jue
;
Zhang, Yanbo
;
Zhu, Shenghua
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/05
proliferation
bromodeoxyuridine (BrdU)
immunohistochemistry
plaque
memory
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