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厦门大学 [5]

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	Visualization of Alzheimer's Disease Related alpha-/beta-/gamma-Secretase Ternary Complex by Bimolecular Fluorescence Complementation Based Fluorescence Resonance Energy Transfer 期刊论文 FRONTIERS IN MOLECULAR NEUROSCIENCE, 2018, 卷号: 11, 期号: 1, 页码: 431 作者: Wang, Xin; Pei, Gang 收藏 \| 浏览/下载：28/0 \| 提交时间：2019/04/28 Amyloid Precursor Protein Beta-secretase App Site Cleavage Adam10 Bace1 Localization Dimerization Endocytosis
	Small molecule lx2343 ameliorates cognitive deficits in ad model mice by targeting both amyloid beta production and clearance 期刊论文 Acta pharmacologica sinica, 2016, 卷号: 37, 期号: 10, 页码: 1281-1297 作者: Guo, Xiao-dan; Sun, Guang-long; Zhou, Ting-ting; Xu, Xin; Zhu, Zhi-yuan 收藏 \| 浏览/下载：39/0 \| 提交时间：2019/05/09 Alzheimer's disease N-(1,3-benzodioxol-5-yl)-2-[5-chloro-2-methoxy(phenylsulfonyl)anilino]acetamide (lx2343) Streptozotocin Amyloid beta Pi3k Autophagy App/ps1 transgenic mice Cognitive deficit Bace1
	Small molecule LX2343 ameliorates cognitive deficits in AD model mice by targeting both amyloid beta production and clearance 期刊论文 ACTA PHARMACOLOGICA SINICA, 2016, 卷号: 37, 期号: 10, 页码: 1281-1297 作者: Guo, Xiao-dan; Sun, Guang-long; Zhou, Ting-ting; Xu, Xin; Zhu, Zhi-yuan 收藏 \| 浏览/下载：16/0 \| 提交时间：2019/01/08 Alzheimer's disease N-(1,3-benzodioxol-5-yl)-2-[5-chloro-2-methoxy(phenylsulfonyl)anilino]acetamide (LX2343) streptozotocin amyloid beta BACE1 PI3K autophagy APP/PS1 transgenic mice cognitive deficit
	Trafficking regulation of proteins in Alzheimer's disease 期刊论文 http://dx.doi.org/10.1186/1750-1326-9-6, 2014 Jiang, Shangtong; Li, Yanfang; Zhang, Xian; Bu, Guojun; Xu, Huaxi; Zhang, Yun-wu; 卜国军; 许华曦; 张云武收藏 \| 浏览/下载：3/0 \| 提交时间：2015/07/22 AMYLOID PRECURSOR PROTEIN TRANS-GOLGI NETWORK GAMMA-SECRETASE ACTIVITY SORTILIN-RELATED RECEPTOR BETA PEPTIDE GENERATION NECROSIS-FACTOR-ALPHA INTRACELLULAR TRAFFICKING ENDOPLASMIC-RETICULUM APOLIPOPROTEIN-E CLEAVING ENZYME
	SCG10 promotes non-amyloidogenic processing of amyloid precursor protein by facilitating its trafficking to the cell surface 期刊论文 human molecular genetics, 2013 Wang, Jingjing; Shan, Chunyan; Cao, Wenyuan; Zhang, Chen; Teng, Junlin; Chen, Jianguo 收藏 \| 浏览/下载：3/0 \| 提交时间：2015/11/13 MICROTUBULE-DESTABILIZING ACTIVITY GROWTH-ASSOCIATED PROTEIN BETA-SECRETASE CLEAVAGE ALZHEIMERS-DISEASE AXONAL-TRANSPORT GAMMA-SECRETASE MOUSE MODEL RAT-BRAIN IN-VITRO STATHMIN
	Structure-activity relationship of memapsin 2: implications on physiological functions and Alzheimer's disease 期刊论文 ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2013, 卷号: 45, 期号: 8, 页码: 613-621 作者: Li Xiaoman; Hong Lin; Coughlan Kathleen; Wang Liang; Cao Liu 收藏 \| 浏览/下载：1/0 \| 提交时间：2021/02/02 AMYLOID PRECURSOR PROTEIN BETA-SECRETASE BACE1 GATED SODIUM-CHANNELS CLEAVING ENZYME GGA PROTEINS ASPARTYL PROTEASE NEURONAL-ACTIVITY GENETIC DELETION CYTOSOLIC DOMAIN ALPHA-SECRETASE memapsin 2 BACE1 beta-amyloid subsite specificity activity prediction
	Structure-activity relationship of memapsin 2: implications on physiological functions and Alzheimer's disease 期刊论文 ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2013, 卷号: 45, 期号: 8, 页码: 613-621 作者: Li Xiaoman; Hong Lin; Coughlan Kathleen; Wang Liang; Cao Liu 收藏 \| 浏览/下载：0/0 \| 提交时间：2021/02/02 AMYLOID PRECURSOR PROTEIN BETA-SECRETASE BACE1 GATED SODIUM-CHANNELS CLEAVING ENZYME GGA PROTEINS ASPARTYL PROTEASE NEURONAL-ACTIVITY GENETIC DELETION CYTOSOLIC DOMAIN ALPHA-SECRETASE memapsin 2 BACE1 beta-amyloid subsite specificity activity prediction
	Huperzine A Alleviates Synaptic Deficits and Modulates Amyloidogenic and Nonamyloidogenic Pathways in APPswe/PS1dE9 Transgenic Mice 期刊论文 JOURNAL OF NEUROSCIENCE RESEARCH, 2012, 卷号: 90, 期号: 2, 页码: 508-517 作者: Wang, Ying; Tang, Xi Can; Zhang, Hai Yan 收藏 \| 浏览/下载：16/0 \| 提交时间：2019/01/08 Alzheimer's disease huperzine A beta-amyloid ADAM10 BACE1
	Differential regulation of BACE1 expression by oxidative and nitrosative signals 期刊论文 http://dx.doi.org/10.1186/1750-1326-6-17, 2011 Kwak, Y. D.; Wang, R. S.; Li, J. J.; Zhang, Y. W.; Xu, H. X.; Liao, F. F.; 张云武收藏 \| 浏览/下载：2/0 \| 提交时间：2013/12/12 AMYLOID PRECURSOR PROTEIN BETA-SECRETASE ACTIVITY MILD COGNITIVE IMPAIRMENT ALZHEIMERS-DISEASE NITRIC-OXIDE A-BETA TRANSCRIPTIONAL REGULATION S-NITROSYLATION GENE-EXPRESSION INCREASED RISK
	APP processing in Alzheimer's disease 期刊论文 http://dx.doi.org/10.1186/1756-6606-4-3, 2011 Zhang, Yun-Wu; Thompson, Robert; Zhang, Han; Xu, Huaxi; 张云武收藏 \| 浏览/下载：4/0 \| 提交时间：2013/12/12 AMYLOID-PRECURSOR-PROTEIN TRANS-GOLGI NETWORK NECROSIS-FACTOR-ALPHA RECEPTOR-RELATED PROTEIN INTRANEURONAL A-BETA-42 ACCUMULATION REGULATES INTRACELLULAR TRAFFICKING ESTROGEN-REPLACEMENT THERAPY GAMMA-SECRETASE ACTIVITY BETA-PEPTIDE PRODUCTION A-

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