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醒脾解郁方对轻中度抑郁症肝郁脾虚证患者的临床疗效研究
期刊论文
北京中医药大学学报, 2021, 卷号: 44, 期号: 01, 页码: 83-91
作者:
李阳
;
郭蓉娟
;
赵钟辉
;
于姚
;
郭建友
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2021/05/20
抑郁症
肝郁脾虚证
醒脾解郁方
线粒体
腺嘌呤核苷三磷酸
Enhanced acetic acid stress tolerance and ethanol production in Saccharomyces cerevisiae by modulating expression of the de novo purine biosynthesis genes
期刊论文
BIOTECHNOLOGY FOR BIOFUELS, 2019, 卷号: 12, 页码: 13
作者:
Zhang, Ming-Ming
;
Xiong, Liang
;
Tang, Ya-Jie
;
Mehmood, Muhammad Aamer
;
Zhao, Zongbao Kent
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  |  
浏览/下载:66/0
  |  
提交时间:2019/06/20
Saccharomyces cerevisiae
Yeast stress tolerance
de novo purine biosynthesis
ADE17
Global amino acid profiles
Identification of potential AMPK activator by pharmacophore modeling, molecular docking and QSAR study
期刊论文
COMPUTATIONAL BIOLOGY AND CHEMISTRY, 2019, 卷号: 79, 页码: 165-176
作者:
Li, Yingying
;
Peng, Jiale
;
Li, Penghua
;
Du, Haibo
;
Li, Yaping
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  |  
浏览/下载:66/0
  |  
提交时间:2019/07/29
Pharmacophore modeling
Molecular docking
Quantitative structure activity relationship (QSAR)
Molecular dynamics
AMPK
Activator
Electrostatic interactions determine entrance/release order of substrates in the catalytic cycle of adenylate kinase
期刊论文
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS, 2019, 卷号: 87, 期号: 4, 页码: 337-347
作者:
Ye, Chun
;
Ding, Chengtao
;
Ma, Rongsheng
;
Wang, Junfeng
;
Zhang, Zhiyong
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  |  
浏览/下载:9/0
  |  
提交时间:2020/07/14
conformational transition
domain motion
enhanced sampling
molecular dynamics simulation
protein dynamics
Structures of AMP-activated protein kinase bound to novel pharmacological activators in phosphorylated, non-phosphorylated, and nucleotide-free states
期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2019, 卷号: 294, 期号: 3, 页码: 953-967
作者:
Yan, Yan
;
Zhou, X. Edward
;
Novick, Scott J.
;
Shaw, Simon J.
;
Li, Yingwu
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  |  
浏览/下载:14/0
  |  
提交时间:2020/07/01
AMP-activated kinase (AMPK)
AMP
hydrogen exchange mass spectrometry
X-ray crystallography
phosphorylation
activation loop phosphorylation
ADaM site
CBS3
R734
R739
metabolic disorder
energy sensor
Structure and Physiological Regulation of AMPK
期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2018, 卷号: 19, 期号: 11
作者:
Yan, Yan
;
Zhou, X. Edward
;
Xu, H. Eric
;
Melcher, Karsten
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浏览/下载:82/0
  |  
提交时间:2019/01/08
energy metabolism
AMPK
activation loop
AID
-linker
-linker
CBS
LKB1
CaMKK2
RIM
Enhancement of Glucose Utilization by Loesenerine through AMPK Activation in Myotubes
期刊论文
CHEMICAL & PHARMACEUTICAL BULLETIN, 2018, 卷号: 66, 期号: 9, 页码: 885-886
作者:
Wang, Luo-Na
;
Jiang, Hao-Wen
;
Li, Jin-Long
;
Li, Jing-Ya
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  |  
浏览/下载:23/0
  |  
提交时间:2019/01/08
loesenerine
spermidine alkaloid
AMP-activated protein kinase activation
glucose uptake
细胞内两种能量代谢物 的检测及卤代醌对细胞内 ATP 的影响
学位论文
北京: 中国科学院生态环境研究中心, 2018
作者:
朱会宇
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  |  
浏览/下载:5/0
  |  
提交时间:2019/08/01
高效液相色谱
Fructose-1, 6-diphosphate
Quinones
Atp
果糖 1,6 二磷酸
醌类化合物
三磷酸腺苷
hplc
The pharmacological properties of Ophiocordyceps xuefengensis revealed by transcriptome analysis
期刊论文
Journal of Ethnopharmacology, 2018, 卷号: 219, 页码: 195-201
作者:
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2019/12/23
2′–C–3′–dA
2′–carbonyl–3′–deoxyadenosine
3′–AMP
adenosine–3′–monophosphate
5′–ADP
adenosine–5′–diphosphate
5′–P–3′–dADP
3′–deoxyadenosine–5′–diphosphate
COG
Clusters of Orthologous Groups of proteins
DAD
diode array detection
GO
Gene Ontology
HPLC
high-performance liquid chromatography
KO
KEGG Ortholog database
Nr
NCBI non–redundant protein sequences
Nt
NCBI non–redundant nucleotide sequences
Pfam
Protein family
Q-TOF-MS
quadrupole-time-of-flight mass spectrometry
RNR
ribonucleotide trisphosphate reductase
Swiss–Prot
A manually annotated and reviewed protein sequence database
Traditional Chinese medicine
Transcriptomics
Caterpillar fungi
Cordycepin
HPLC–DAD–Q–TOF–MS
The pharmacological properties of Ophiocordyceps xuefengensis revealed by transcriptome analysis
期刊论文
Journal of Ethnopharmacology, 2018, 卷号: 219, 页码: 195-201
作者:
Jin, Jian
;
Kang, Wenli
;
Zhong, Can
;
Qin, You
;
Zhou, Rongrong
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2019/12/27
2′–C–3′–dA
2′–carbonyl–3′–deoxyadenosine
3′–AMP
adenosine–3′–monophosphate
5′–ADP
adenosine–5′–diphosphate
5′–P–3′–dADP
3′–deoxyadenosine–5′–diphosphate
COG
Clusters of Orthologous Groups of proteins
DAD
diode array detection
GO
Gene Ontology
HPLC
high-performance liquid chromatography
KO
KEGG Ortholog database
Nr
NCBI non–redundant protein sequences
Nt
NCBI non–redundant nucleotide sequences
Pfam
Protein family
Q-TOF-MS
quadrupole-time-of-flight mass spectrometry
RNR
ribonucleotide trisphosphate reductase
Swiss–Prot
A manually annotated and reviewed protein sequence database
Traditional Chinese medicine
Transcriptomics
Caterpillar fungi
Cordycepin
HPLC–DAD–Q–TOF–MS
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