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Polyoxypregnanes as safe, potent, and specific ABCB1-inhibitory pro-drugs to overcome multidrug resistance in cancer chemotherapy in vitro and in vivo
期刊论文
ACTA PHARMACEUTICA SINICA B, 2021, 卷号: 11, 期号: 7, 页码: 1885-1902
作者:
Wu, Xu
;
Yin, Chun
;
Ma, Jiang
;
Chai, Stella
;
Zhang, Chunyuan
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2021/11/04
Multidrug resistance
ABCB1
Polyoxypregnane
Combination chemotherapy
Marsdenia tenacissima
The Nonclinical Pharmacokinetics and Prediction of Human Pharmacokinetics of SPH3127, a Novel Direct Renin Inhibitor
期刊论文
EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS, 2020, 卷号: 45, 期号: 1, 页码: 15-26
作者:
Zhang, Leduo
;
Mao, Yu
;
Gao, Zhiwei
;
Chen, Xiaoyan
;
Li, Xin
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  |  
浏览/下载:49/0
  |  
提交时间:2020/07/01
Global warming accelerates uptake of atmospheric mercury in regions experiencing glacier retreat
期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2020, 卷号: 117, 期号: 4, 页码: 2049–2055
作者:
Xun Wang
;
Ji Luo
;
Wei Yuan
;
Che-Jen Lin
;
(4,5)
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  |  
浏览/下载:29/0
  |  
提交时间:2020/04/01
global warming
glacier retreat
atmospheric mercury deposition
leflunomideincreasedtherenalexposureofacyclovirbyinhibitingoat13andmrp2
期刊论文
actapharmacologicasinica, 2020, 卷号: 41, 期号: 1, 页码: 129
作者:
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浏览/下载:90/0
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提交时间:2020/07/01
leflunomide
teriflunomide
acyclovir
organic anion transporter
multidrug resistance associated protein (MRP) 2
drugdrug interaction
pharmacokinetics
Leflunomide increased the renal exposure of acyclovir by inhibiting OAT1/3 and MRP2
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 卷号: 41, 期号: 1, 页码: 129-137
作者:
Liao, Xiao-ying
;
Deng, Qiang-qiang
;
Han, Li
;
Wu, Zhi-tao
;
Peng, Zhao-liang
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  |  
浏览/下载:59/0
  |  
提交时间:2020/07/01
leflunomide
teriflunomide
acyclovir
organic anion transporter
multidrug resistance associated protein (MRP) 2
drug-drug interaction
pharmacokinetics
Temporal variation in soil respiration and its sensitivity to temperature along a hydrological gradient in an alpine wetland of the Tibetan Plateau
期刊论文
AGRICULTURAL AND FOREST METEOROLOGY, 2020, 卷号: 282
作者:
Yu, Lingfei
;
Wang, Hao
;
Wang, Yonghui
;
Zhang, Zhenhua
;
Chen, Litong
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  |  
浏览/下载:33/0
  |  
提交时间:2022/03/01
Meadow
Q(10)
Soil CO2 flux
Soil water content
Spring thawing
Wetland
Carboxylesterase 2 and Intestine Transporters Contribute to the Low Bioavailability of Allisartan, a Prodrug of Exp3174 for Hypertension Treatment in Humans
期刊论文
DRUG METABOLISM AND DISPOSITION, 2019, 卷号: 47, 期号: 8, 页码: 843-853
作者:
Li, Xiuli
;
Sun, Jingchao
;
Guo, Zitao
;
Zhong, Dafang
;
Chen, Xiaoyan
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  |  
浏览/下载:26/0
  |  
提交时间:2020/07/01
Metagenomic characterization of antibiotic resistance genes in Antarctic soils
期刊论文
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2019, 卷号: 176, 页码: 300-308
作者:
Yuan, Ke
;
Yu, Ke
;
Yang, Ruiqiang
;
Zhang, Qinghua
;
Yang, Ying
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2020/09/10
Antibiotic resistance genes (ARGs)
Metagenome
Antarctica
Soils
Resistance level
Study on the association between drug-resistance and gene mutations of the active efflux pump acrAB-tolC gene and its regulatory genes
期刊论文
MOLECULAR MEDICINE REPORTS, 2018, 卷号: 17, 期号: 6, 页码: 8228-8236
作者:
Ma, Quan-Ping
;
Su, Liang
;
Liu, Jing-Wen
;
Yao, Ming-Xiao
;
Yuan, Guang-Ying
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/11
Shigella
drug resistance
integrons
active efflux pump acrAB-tolC
marOR genes
Depth heterogeneity of soil organic carbon dynamicsin a heavily grazed alpine meadow on thenortheastern Tibetan Plateau: Aradiocarbon-based approach
期刊论文
Journal of Geophysical Research: Biogeosciences, 2017, 卷号: 122, 期号: 7, 页码: 1775-1788
作者:
Yu,SY(Yu,Shiyong)
;
Cheng,P(Cheng,Peng)
;
Hou,ZF(Hou,Zhangfang)
;
Yu,Shiyong
;
He,HL(He,Honglin)
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  |  
浏览/下载:20/0
  |  
提交时间:2018/10/22
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