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上海药物研究所 [6]
山东大学 [2]
大连化学物理研究所 [1]
吉林大学白求恩第一医... [1]
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期刊论文 [12]
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Prodrug nanoparticles rationally integrating stroma modification and chemotherapy to treat metastatic pancreatic cancer
期刊论文
BIOMATERIALS, 2021, 卷号: 278
作者:
Wang, Liying
;
Liu, Zimo
;
Zhou, Quan
;
Gu, Sufang
;
Liu, Xiangsheng
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2021/11/29
Pancreatic cancer
Polymeric prodrug
Calcipotriol
Cancer-associated fibroblast
Metastasis
A validated HPLC-MS/MS method for determination of simmitecan and its metabolite chimmitecan in human plasma and its application to a pharmacokinetic study in Chinese patients with advanced solid tumor
期刊论文
JOURNAL OF SEPARATION SCIENCE, 2021, 页码: 8
作者:
Zhou, Jun
;
Zhan, Yan
;
Zhong, Dafang
;
Chen, Xiaoyan
;
Zhang, Yifan
收藏
  |  
浏览/下载:74/0
  |  
提交时间:2021/11/04
chimmitecan
mass spectrometry
pharmacokinetics
simmitecan
solid tumors
Co-Prodrugs of 7-Ethyl-10-hydroxycamptothecin and Vorinostat with in Vitro Hydrolysis and Anticancer Effects
期刊论文
ACS OMEGA, 2020, 卷号: 5, 期号: 1, 页码: 350-357
作者:
Liu, Shuangxi
;
Hu, Zonglong
;
Zhang, Qiumeng
;
Zhu, Qiwen
;
Chen, Yi
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2020/07/01
Bioinspired Multivalent Peptide Nanotubes for Sialic Acid Targeting and Imaging-Guided Treatment of Metastatic Melanoma
期刊论文
SMALL, 2019, 卷号: 15, 期号: 22, 页码: 11
作者:
Lei, Li
;
Xu, Zhiai
;
Hu, Xianli
;
Lai, Yi
;
Xu, Jie
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2020/07/01
combination therapy
imaging-guided treatment
multivalent targeting
peptide nanotubes
sialic acid
New Insights into SN-38 Glucuronidation: Evidence for the Important Role of UDP Glucuronosyltransferase 1A9
期刊论文
BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY, 2018, 卷号: 122, 期号: 4, 页码: 424-428
作者:
Xiao, Ling
;
Zhu, Liangliang
;
Li, Wenjuan
;
Li, Conghu
;
Cao, Yunfeng
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2019/06/20
Intratumoral Injection Administration of Irinotecan-Loaded Microspheres: In Vitro and In Vivo Evaluation
期刊论文
AAPS PHARMSCITECH, 2018, 卷号: 19, 期号: 8, 页码: 3829-3838
作者:
Zhu, Shengjun
;
Dou, Mingjin
;
Huang, Guihua
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/11
irinotecan
intratumor-administration
microspheres
7-ethyl-10-hydroxycamptothecin
lactone ring structure
Crystal Structures and Vapor-Induced Crystalline Transformation of 7-Ethyl-10-Hydroxycamptothecin Pseudopolymorphs
期刊论文
JOURNAL OF PHARMACEUTICAL SCIENCES, 2017, 卷号: 106, 期号: 10, 页码: 2998-3004
作者:
Fang, Lan
;
Wang, Lei
;
Yao, Changlin
;
Song, Shuang
;
Wu, Zexin
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/16
crystal structure
hydrates/solvates
crystallization
pseudopolymorph
transformation
Synthesis of 7-Triazole-substituted Camptothecin via Click Chemistry and Evaluation of in vitro Antitumor Activity
期刊论文
CHINESE JOURNAL OF CHEMISTRY, 2014, 卷号: 32, 期号: 2, 页码: 157-162
作者:
Wang, Lei
;
Yuan, Wei
;
Zhang, Jie
;
Tong, Linjiang
;
Luo, Yu
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2019/01/08
camptothecin
7-triazole-substituted camptothecin
click chemistry
antitumor
Synthesis and Biological Evaluation of Novel 10-Substituted-7-ethyl-10-hydroxycamptothecin (SN-38) Prodrugs
期刊论文
MOLECULES, 2014, 卷号: 19, 期号: 12
作者:
Wu, Di
;
Zhou, Mo
;
Liu, Meixia
;
He, Xinhua
;
Yu, Hong
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/05
antitumor agent
camptothecins
prodrugs
SN-38
Combination of chemotherapy and photodynamic therapy using graphene oxide as drug delivery system
期刊论文
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY, 2014, 卷号: 135
作者:
Zhou, Lin
;
Zhou, Lin
;
Wei, Shaohua
;
Ge, Xuefeng
;
Zhou, Jiahong
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/19
Hypocrellin A
7-Ethyl-10-hydroxycamptothecin
Graphene oxide
Combination therapy
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