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上海药物研究所 [14]
华中师范大学 [12]
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Discovery of 5-Benzylidene-2-phenyl-1,3-dioxane-4,6-diones as Highly Potent and Selective SIRT1 Inhibitors
期刊论文
ACS MEDICINAL CHEMISTRY LETTERS, 2021, 卷号: 12, 期号: 3, 页码: 397-403
作者:
Li, Chunpu
;
Hu, Sha-Sha
;
Yang, Lisheng
;
Wang, Min
;
Long, Jian-Dong
收藏
  |  
浏览/下载:57/0
  |  
提交时间:2021/05/24
SIRT1
inhibitor
structure-activity relationship
interaction
deacetylase
Design, Synthesis, and Biological Evaluation of 8-Mercapto-3,7-Dihydro-1H-Purine-2,6-Diones as Potent Inhibitors of SIRT1, SIRT2, SIRT3, and SIRT5
期刊论文
MOLECULES, 2020, 卷号: 25, 期号: 12, 页码: 18
作者:
Han, Haozhen
;
Li, Chunpu
;
Li, Man
;
Yang, Lisheng
;
Zhao, Sen
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  |  
浏览/下载:38/0
  |  
提交时间:2020/12/24
sirtuins
inhibitor
structure-activity relationship
deacetylase
Characterization of Carbonyl Disinfection By-Products During Ozonation, Chlorination, and Chloramination of Dissolved Organic Matters
期刊论文
ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2020, 卷号: 54, 期号: 4, 页码: 2218-2227
作者:
Liu, Xueke
;
Liu, Ruirui
;
Zhu, Bao
;
Ruan, Ting
;
Jiang, Guibin
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  |  
浏览/下载:18/0
  |  
提交时间:2021/09/14
Straightforward synthesis, characterization, and cytotoxicity evaluation of hybrids of natural alkaloid evodiamine/rutaecarpine and thieno[2,3-d]pyrimidinones
期刊论文
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2020, 卷号: 22, 期号: 1, 页码: 69-82
作者:
Nie, LF (Nie, Li-Fei)[ 1,2 ]
;
Wang, SS (Wang, Si-Si)[ 3 ]
;
Cao, JG (Cao, Jian-Guo)[ 3 ]
;
Liu, FZ (Liu, Fei-Ze)[ 1,2 ]
;
Xiamuxi, HBM (Xiamuxi, Hainimu)[ 1,2 ]
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  |  
浏览/下载:159/0
  |  
提交时间:2020/01/15
Thieno[2
3-d]pyrimidinone
evodiamine
rutaecarpine
hybrid
cytotoxicity
CO2 involved synthesis of quinazoline-2,4(1H,3H)-diones in water using melamine as a thermoregulated catalyst
期刊论文
CANADIAN JOURNAL OF CHEMISTRY, 2019, 卷号: 97, 期号: 3, 页码: 212-218
作者:
Zhao, Guo-Ying
;
Mu, Ling-Ling
;
Ullah, Latif
;
Wang, Meng
;
Li, Hong-Ping
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  |  
浏览/下载:45/0
  |  
提交时间:2019/04/03
quinazoline-2
carbon dioxide
water
thermoregulated catalyst
cycloaddition
4(1H
3H)-diones
Interaction of benzo[a]pyrene with Cu(II)-montmorillonite: Generation and toxicity of environmentally persistent free radicals and reactive oxygen species
期刊论文
ENVIRONMENT INTERNATIONAL, 2019, 卷号: 129, 期号: 8, 页码: 154-163
作者:
Zhao, S (Zhao, Song)[ 1 ]
;
Miao, D (Miao, Duo)[ 1 ]
;
Zhu, KC (Zhu, Kecheng)[ 1 ]
;
Tao, KL (Tao, Kelin)[ 1 ]
;
Wang, CY (Wang, Chuanyi)[ 2 ]
收藏
  |  
浏览/下载:109/0
  |  
提交时间:2019/06/21
Environmentally persistent free radicals
Benzo[a]pyrene
Montmorillonite
Soil
Toxicity
Rhodium(III)-Catalyzed Oxidative [3+2] Annulation of 2-Acetyl-1-arylhydrazines with Maleimides: Synthesis of Pyrrolo[3,4-b]indole-1,3-diones
期刊论文
ORGANIC LETTERS, 2019, 卷号: 21, 页码: 8563-8567
作者:
Li, He
;
Zhang, Sheng
;
Feng, Xiujuan
;
Yu, Xiaoqiang
;
Yamamoto, Yoshinori
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  |  
浏览/下载:0/0
  |  
提交时间:2019/12/02
Succinimide-Based Ionic Liquids: An Efficient and Versatile Platform for Transformation of CO2 into Quinazoline-2,4(1H,3H)-diones under Mild and Solvent-Free Conditions
期刊论文
ACS SUSTAINABLE CHEMISTRY & ENGINEERING, 2019, 卷号: 7, 期号: 15, 页码: 13517-13522
作者:
Liu, Fusheng
;
Ping, Ran
;
Zhao, Penghui
;
Gu, Yongqiang
;
Gao, Jun
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2019/12/11
Carbon dioxide
Quinazoline-2,4(1H,3H)-dione
Succinimide-based ionic
liquids
Homogeneous catalysis
Multifunctional catalyst
Design, synthesis and biological evaluation of 3-hydroxyquinazoline-2,4(1H, 3H)-diones as dual inhibitors of HIV-1 reverse transcriptase-associated RNase H and integrase
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2019, 卷号: 27, 期号: 17, 页码: 3836-3845
作者:
Gao, Ping
;
Cheng, Xiqiang
;
Sun, Lin
;
Song, Shu
;
Alvarez, Mar
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/11
HIV-1
RNase H
Integrase
Dual inhibitors
Synthesis of Novel Analogs of Thieno[2,3-d] Pyrimidin-4(3H)-ones as Selective Inhibitors of Cancer Cell Growth
期刊论文
BIOMOLECULES, 2019, 卷号: 9, 期号: 10, 页码: 1-10
作者:
Zhang, S (Zhang, Sheng)[ 1 ]
;
Liu, FZ (Liu, Feize)[ 2,3 ]
;
Hou, XL (Hou, Xueling)[ 2 ]
;
Cao, JG (Cao, Jianguo)[ 1 ]
;
Dai, XL (Dai, Xiling)[ 1 ]
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2020/01/15
thienopyrimidine
thieno[2,3-d] pyrimidinone
anticancer
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