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大连理工大学 [24]
上海药物研究所 [4]
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大连化学物理研究所 [1]
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期刊论文 [29]
会议论文 [3]
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Naphthalimide and quinoline derivatives as inhibitors for insect N-acetyl-beta-D-hexosaminidase
期刊论文
CHINESE CHEMICAL LETTERS, 2019, 卷号: 30, 页码: 977-980
作者:
Yang, Huibin
;
Qi, Huitang
;
Liu, Tian
;
Shao, Xusheng
;
Yang, Qing
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/12/02
OfHex1 inhibitors
Structure-activity relationship
Naphthalimide derivatives
Quinoline derivatives
Molecular docking
Glycosyl triazoles as novel insect beta-N-acetylhexosaminidase OfHex1 inhibitors: Design, synthesis, molecular docking and MD simulations
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2019, 卷号: 27, 页码: 2315-2322
作者:
Dong, Lili
;
Shen, Shengqiang
;
Chen, Wei
;
Lu, Huizhe
;
Xu, Dongdong
收藏
  |  
浏览/下载:61/0
  |  
提交时间:2019/12/02
beta-N-acetyl-D-hexosaminidase
OfHex1
Glycosyl triazoles
Enzyme inhibitors
Molecular docking
MD simulations
Design and synthesis of thiazolylhydrazone derivatives as inhibitors of chitinolytic N-acetyl-beta-D-hexosaminidase
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2018, 卷号: 26, 页码: 5420-5426
作者:
Yang, Huibin
;
Liu, Tian
;
Qi, Huitang
;
Huang, Zhisong
;
Hao, Zesheng
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/12/02
Glycoside hydrolase family 18 and 20 enzymes are novel targets of the traditional medicine berberine
期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2018, 卷号: 293, 页码: 15429-15438
作者:
Duan, Yanwei
;
Liu, Tian
;
Zhou, Yong
;
Dou, Tongyi
;
Yang, Qing
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2019/12/02
glycoside hydrolase
chitinase
inhibitor
protein crystallization
human
insect
-N-acetyl-D-hexosaminidase
berberine
Revisiting glycoside hydrolase family 20 beta-N-acetyl-d-hexosaminidases: Crystal structures, physiological substrates and specific inhibitors.
期刊论文
Biotechnology advances, 2018, 卷号: 36, 页码: 1127-1138
作者:
Liu, Tian
;
Duan, Yanwei
;
Yang, Qing
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/02
beta-N-acetyl-D-hexosaminidase
Glycoside hydrolase
Crystal structure
Substrate
Catalytic mechanism
Inhibitor
Drug
Pesticide
Exploring NAG-thiazoline and its derivatives as inhibitors of chitinolytic beta-acetylglucosaminidases
期刊论文
FEBS LETTERS, 2015, 卷号: 589, 期号: 1, 页码: 110-116
作者:
Liu, Tian
;
Xia, Meng
;
Zhang, Haitao
;
Zhou, Hao
;
Wang, Jing
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2019/01/08
beta-Acetylglucosaminidase
Chitinolytic enzyme
Inhibitor
NGT
Enzymatic characterizations and activity regulations of N-acetyl-beta-D-glucosaminidase from the spermary of Nile tilapia (Oreochromis niloticus)
期刊论文
http://dx.doi.org/10.1016/j.jbiosc.2013.07.014, 2014
Zhang, Wei-Ni
;
Bai, Ding-Ping
;
Huang, Yi-Fan
;
Hu, Chong-Wei
;
Chen, Qing-Xi
;
Huang, Xiao-Hong
;
张伟妮
;
陈清西
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2015/07/22
CRAB SCYLLA-SERRATA
D-HEXOSAMINIDASE
PURIFICATION
ACETYLGLUCOSAMINIDASE
ACETYLHEXOSAMINIDASE
EXPRESSION
GENE
L.
Inactivation kinetics of formaldehyde on N-acetyl-beta-d-glucosaminidase from Nile tilapia (Oreochromis niloticus)
期刊论文
http://dx.doi.org/10.1007/s10695-013-9866-7, 2014
Zhang, Wei-Ni
;
Bai, Ding-Ping
;
Lin, Xin-Yu
;
Chen, Qing-Xi
;
Huang, Xiao-Hong
;
Huang, Yi-Fan
;
张伟妮
;
陈清西
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2015/07/22
INHIBITORY KINETICS
HEXOSAMINIDASE
EXPRESSION
VANNAMEI
EGGS
Exploring unsymmetrical dyads as efficient inhibitors against the insect beta-N-acetyl-D-hexosaminidase OfHex2
期刊论文
BIOCHIMIE, 2014, 卷号: 97, 页码: 152-162
作者:
Chen, Qi
;
Guo, Peng
;
Xu, Lin
;
Liu, Tian
;
Qian, Xuhong
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/09
beta-N-Acetyl-D-hexosaminidase
Enzyme inhibitors
Molecular docking
Naphthalimide
Tryptophan fluorescence titration
Structural insights into cellulolytic and chitinolytic enzymes revealing crucial residues of insect β-N-acetyl-D-hexosaminidase
会议论文
第十一届全国酶学学术讨论会暨邹承鲁诞辰90周年纪念会论文集中国生物化学与分子生物学会, 无锡, 2013-05-16
作者:
Liu T(刘田)
;
Zhou Y(周勇)
;
Chen L(陈磊)
;
Chen W(陈威)
;
Liu L(刘霖)
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/13
crystal strucutre chitin cellulose β-N-acetyl-D-hexosaminidase β-glucosidase
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