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上海药物研究所 [21]
长春应用化学研究所 [10]
厦门大学 [7]
北京大学 [7]
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期刊论文 [89]
学位论文 [5]
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A camptothecin-based, albumin-binding prodrug enhances efficacy and safety in vivo
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 226, 页码: 11
作者:
Cheng, Zhiyang
;
Huang, Ying
;
Shen, Qianqian
;
Zhao, Yangrong
;
Wang, Lei
收藏
  |  
浏览/下载:87/0
  |  
提交时间:2021/11/04
Cancer
beta-glucuronidase
Bioconjugation
Albumin
Camptothecin
A novel GPR120-selective agonist promotes insulin secretion and improves chronic inflammation
期刊论文
LIFE SCIENCES, 2021, 卷号: 269, 页码: 8
作者:
Yang, Liu
;
Lei, Xian-Tao
;
Huang, Qi
;
Wang, Ting
;
Sun, Hong-Bin
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2021/05/24
GPR120 agonist
Insulin secretion
Anti-inflammation
Insulin resistance
Type 2 diabetes mellitus
Design, synthesis, and biological evaluation of tetrahydroisoquinolines derivatives as novel, selective PDE4 inhibitors for antipsoriasis treatment
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 211, 页码: 20
作者:
Zhang, Rui
;
Li, Heng
;
Zhang, Xianglei
;
Li, Jian
;
Su, Haixia
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2021/05/24
PDE4 inhibitors
Tetrahydroisoquinoline
Antipsoriasis
Main Chain-Type Block Copolymers through Atom Transfer Radical Polymerization from Double-Decker-Shaped Polyhedral Oligomeric Silsesquioxane Hybrids
期刊论文
POLYMERS, 2020, 卷号: 12, 期号: 2
作者:
Chen, Wei-Cheng
;
Tsao, Yu-Hsuan
;
Wang, Chih-Feng
;
Huang, Chih-Feng
;
Dai, Lizong
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2020/12/16
SELF-ASSEMBLED STRUCTURES
HYDROGEN-BONDING STRENGTH
NANOPARTICLE COMPOSITES
DRUG-RELEASE
BLENDS
MISCIBILITY
Stepwise targeting and responsive lipid-coated nanoparticles for enhanced tumor cell sensitivity and hepatocellular carcinoma therapy
期刊论文
THERANOSTICS, 2020, 卷号: 10, 期号: 8, 页码: 3722-3736
作者:
Li, Ying
;
Miao, Yunqiu
;
Chen, Mingshu
;
Chen, Xi
;
Li, Feifei
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  |  
浏览/下载:29/0
  |  
提交时间:2020/07/01
drug delivery
pH sensitive
charge conversion
tumor targeting
hepatocellular carcinoma
Diethyldithiocarbamate-copper nanocomplex reinforces disulfiram chemotherapeutic efficacy through light-triggered nuclear targeting
期刊论文
THERANOSTICS, 2020, 卷号: 10, 期号: 14, 页码: 6384-6398
作者:
Ren, Liting
;
Feng, Wenya
;
Shao, Jie
;
Ma, Juan
;
Xu, Ming
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2021/09/14
diethyldithiocarbamate
DSF-Cu nanocomplex
light-triggered nuclear targeting
metastasis
epithelial-mesenchymal transition
A facile PEG/thiol-functionalized nanographene oxide carrier with an appropriate glutathione-responsive switch
期刊论文
POLYMER CHEMISTRY, 2020, 卷号: 11, 期号: 12, 页码: 2194-2204
作者:
Hao, BJ
;
Li, W
;
Zhang, S
;
Zhu, Y
;
Li, YJ
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2021/09/06
DRUG-DELIVERY
GRAPHENE OXIDE
CARBON NANOTUBES
COVALENT FUNCTIONALIZATION
PACLITAXEL
NANOPARTICLES
CONJUGATE
GRAPHITE
PRODRUG
Polyphotosensitizer nanogels for GSH-responsive histone deacetylase inhibitors delivery and enhanced cancer photodynamic therapy
期刊论文
Colloids and Surfaces B-Biointerfaces, 2020, 卷号: 188, 页码: 11
作者:
N. Liu,H. S. Liu,H. R. Chen,G. Wang,H. L. Teng and Y. L. Chang
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2021/07/06
Manganese-Based Functional Nanoplatforms: Nanosynthetic Construction, Physiochemical Property, and Theranostic Applicability
期刊论文
ADVANCED FUNCTIONAL MATERIALS, 2019
作者:
Qian, Xiaoqin
;
Han, Xiaoxia
;
Yu, Luodan
;
Xu, Tianming
;
Chen, Yu
收藏
  |  
浏览/下载:108/0
  |  
提交时间:2019/12/31
contrast agents
magnetic resonance imaging
manganese oxide
manganese-based nanoparticles
nanomedicine
Hyaluronic acid/PEGylated amphiphilic nanoparticles for pursuit of selective intracellular doxorubicin release
期刊论文
JOURNAL OF MATERIALS CHEMISTRY B, 2019, 卷号: 7, 页码: 95-102
作者:
Yan, Xiangjie
;
Chen, Qixian
;
An, Jinxia
;
Liu, De-E
;
Huang, Yongkang
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2019/12/02
Biocompatibility
Controlled drug delivery
Molecular biology
Nanoparticles
Organic acids
Polyethylene glycols
Polyethylene oxides
Targeted drug delivery, Amphiphilic co-polymers
Cationic components
Controlled release
Deshielding effects
Functionalized nanoparticles
Microenvironments
Quaternary ammonium salt
Structural rearrangement, Hyaluronic acid
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