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中南大学 [7]
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期刊论文 [7]
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2018 [1]
2017 [1]
2016 [2]
2015 [1]
2014 [1]
2011 [1]
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Metabolomics-based evidence of the hypoglycemic effect of Ge-Gen-Jiao-Tai-Wan in type 2 diabetic rats via UHPLC-QTOF/MS analysis
期刊论文
Journal of Ethnopharmacology, 2018, 卷号: 219, 页码: 299-318
作者:
Wang, Wenbo
;
Zhao, Linlin
;
He, Zhenyu
;
Wu, Ning
;
Li, Qiuxia
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2019/12/03
GGJTW
Ge-Gen-Jiao-Tai-Wan
T2DM
type 2 diabetes mellitus
TCMs
traditional Chinese medicines
UHPLC-QTOF/MS
ultra high performance liquid chromatography coupled with quadrupole-time-of-flight tandem mass spectrometry
BAs
bile acids
Ge-Gen-Jiao-Tai-Wan
Type 2 diabetes
Metabolomics
UHPLC-QTOF/MS
Therapeutic effects
Chinese herbal medicine
An integrated strategy for rapid discovery and identification of the sequential piperine metabolites in rats using ultra high-performance liquid chromatography/high resolution mass spectrometery
期刊论文
Journal of Pharmaceutical and Biomedical Analysis, 2017, 卷号: 146, 页码: 387-401
作者:
Shang, Zhanpeng
;
Cai, Wei
;
Cao, Yanfeng
;
Wang, Fei
;
Wang, Zhibin
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2019/12/03
Piperine
Ultra high-performance liquid chromatography/high resolution mass spectrometry
Metabolic profile
Multiple data processing methods
Reverse molecular assembly strategy
Qualitative analysis of major constituents from Xue Fu Zhu Yu Decoction using ultra high performance liquid chromatography with hybrid ion trap time-of-flight mass spectrometry
期刊论文
Journal of Separation Science, 2016, 卷号: 39, 期号: 17, 页码: 3457-3468
作者:
Fu, Chunyan
;
Xia, Zian
;
Liu, Yonghui
;
Lu, Hongmei*
;
Zhang, Zhimin
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/12/03
Major constituents
Qualitative analysis
Traditional Chinese medicine
Ultra‐high performance liquid chromatography
Xue Fu Zhu Yu Decoction
A strategy for comprehensive identification of sequential constituents using ultra-high-performance liquid chromatography coupled with linear ion trap-Orbitrap mass spectrometer, application study on chlorogenic acids in Flos Lonicerae Japonicae
期刊论文
Talanta, 2016, 卷号: 147, 页码: 16-27
作者:
Zhang, Jia-yu
;
Wang, Zi-jian
;
Li, Yun
;
Liu, Ying
;
Cai, Wei
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2019/12/03
UPLC–LTQ–Orbitrap
ultra-high-performance liquid chromatography coupled with linear ion trap–Orbitrap
MIM
multiple ion monitoring
MTSF
mass spectral trees similarity filter
HRMS
high resolution mass spectrometer
CGAs
chlorogenic acids
FLJ
Flos Lonicerae Japonicae
DPIs
diagnostic product ions
TCMs
Traditional Chinese medicines
LC–MS
liquid chromatography tandem mass spectrometer
FS–PIL–DE
full scan–parent ions list–dynamic exclusion
ESI
electrospray ionization
PMFs
polymethoxylated flavonoids
CID
collision induced dissociation
SIM
selected ion monitoring
TECD
total extraction component detection
CQA
caffeoylquinic acid
DiCQA
dicaffeoylquinic acid
TriCQA
tricaffeoylquinic acid
pCoQA
p-coumaroylquinic acid
FQA
feruloylquinic acid
SQA
sinapoylquinic acid
pCoCQA
p-coumaroylcaffeoylquinic acid
CFQA
caffeoylferuloylquinic acid
pCoSQA
p-coumaroylsinapoylquinic acid
CSQA
caffeoylsinapoylquinic acid
FSQA
feruloylsinapoylquinic acid.
Chlorogenic acids
Ultra-high-performance liquid chromatography coupled with linear ion trap–Orbitrap
Flos Lonicerae Japonicae
Sequential constituents
An ultra high performance liquid chromatography with tandem mass spectrometry method for plasma and cerebrospinal fluid pharmacokinetics of rhein in patients with traumatic brain injury after administration of rhubarb decoction
期刊论文
Journal of Separation Science, 2015, 卷号: 38, 期号: 7, 页码: 1100-1108
作者:
Wang, Yang
;
Fan, Rong
;
Luo, Jiekun
;
Tang, Tao
;
Xing, Zhihua
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2019/12/03
Blood–brain barrier
Pharmacokinetics
Rhubarb
Traumatic brain injury
Ultra high performance liquid chromatography with tandem mass spectrometry
Exploring metabolic syndrome serum profiling based on gas chromatography mass spectrometry and random forest models
期刊论文
Analytica Chimica Acta, 2014, 卷号: 827, 页码: 22-27
作者:
Lin, Zhang
;
Vicente Gonç
;
alves, Carlos M.
;
Dai, Ling
;
Lu, Hong-mei
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2019/12/03
RF
Random forests
MetS
Metabolic syndrome
GC–MS
Gas chromatography–mass spectrometry
UPLC-QTOF-MS
Ultra-performance liquid chromatography quadrupole time-of-flight mass spectrometry
1H NMR
1H Nuclear magnetic resonance
HDL-C
High density lipoprotein-cholesterol
WHO
World Health Organization
NCEP
Nation Cholesterol Education Panel
IDF
International Diabetes Federation
BMI
Body mass index
SBP/DBP
Systolic blood pressure/diastolic blood pressure
TG
Triglyceride
CDS
The Chinese diabetes society
T2DM
Type 2 diabetes mellitus
CVD
Cardio vascular disorder
QC
Quality control
Metabolic syndrome
Serum profiling
GC–MS
Random forest
Biomarker
Pharmacokinetic study of the prokinetic compounds meranzin hydrate and ferulic acid following oral administration of Chaihu-Shugan-San to patients with functional dyspepsia
期刊论文
Journal of Ethnopharmacology, 2011, 卷号: 137, 期号: 1, 页码: 205-213
作者:
Qiu, Xin-Jian
;
Huang, Xi*
;
Chen, Ze-Qi
;
Ren, Ping
;
Huang, Wei
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/03
AUC(0–∞)
area under concentration–time curve from t = 0 to last time
CL/F
apparent clearance
Cmax
maximum plasma concentration
CSS
Chaihu-Shugan-San
C–t
concentration–time
FA
ferulic acid
FD
functional dyspepsia
GE
gastric emptying
HPLC
high performance liquid chromatography
HPMC
hydroxypropylmethyl cellulose
IS
internal standard
IT
intestinal transit
K10
apparent first-order elimination rate constant from the central compartment
K21 and K12
apparent first-order inter compartmental transfer rate constants
Ka
absorption constant
LLOQ
lower limit of quantification
MH
meranzin hydrate
MRM
multiple reaction monitoring
MRT
mean residence time
QC
quality control
RE
relative error
RSD
relative standard deviation
SMZ
sulfamethoxazole
T1/2α
distribution half-life
T1/2β
elimination half-life
TCM
traditional Chinese medicine
Tmax
time to reach peak concentration
UPLC
ultra performance liquid chromatography
UPLC-MS/MS
ultra performance liquid chromatography with tandem mass spectrometry
V1/F
volume of distribution
Meranzin hydrate
Ferulic acid
Chaihu-Shugan-San
Functional dyspepsia
Clinical Pharmacokinetic
Pharmacodynamic
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