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科研机构
中南大学 [11]
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期刊论文 [11]
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2018 [1]
2017 [2]
2016 [1]
2015 [3]
2014 [2]
2013 [1]
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专题:中南大学
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Broad targeting of triptolide to resistance and sensitization for cancer therapy
期刊论文
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, 卷号: 104, 页码: 771-780
作者:
Hou, Zhen-yan
;
Tong, Xiao-pei
;
Peng, Yong-bo
;
Zhang, Bi-Kui*
;
Yan, Miao*
收藏
  |  
浏览/下载:50/0
  |  
提交时间:2019/12/03
ABC
ATP-binding cassette
AKT
V-Akt murine thymoma viral oncogene homolog
ALDH1
aldehyde dehydrogenase 1
AR
androgen receptor
Bad
Bcl-2-associated death promoter
Bak
Bcl-2 homologous antagonist killer
Bax
Bcl-2-associated X protein
Bcl-2
B-cell lymphoma
Bcl-xL
Bcl-extra large
Bcl-xs
Bcl-extra short
BCRP
breast cancer resistance protein
Bid
BH3 interacting domain death agonist
Bik
Bcl-2-interacting killer
BNIP3
Bcl2/adenovirus E1B 19 kDa protein-interacting protein 3
CAF
cancer-associated fibroblast
CAIX
carbonic anhydrase IX
cFLIP
cellular FLICE (FADD-like IL-1β-converting enzyme)-inhibitory protein
ChIP
chromatin immunoprecipitation
CI
Combination Index
cIAP1/2
cellular IAP1/2
CML
chronic myelogenous leukemia
CSC
cancer stem cell
DISC
death-inducing signaling complex
DR
death receptor
DRI
Dose Reduction Index
ECM
extracellular matrix
EMT
epithelial-mesenchymal transition
EpCAM
epithelial cell adhesion molecule
GLUT
glucose transporter
GSK3β
glycogen synthase kinase-3β
HIF-1
hypoxia inducible factor-1
HSF1
heat shock factor 1
HSP
heat shock protein
IAP
inhibitor of apoptosis protein
JNK
c-JUN N-terminal kinase
MAPK
mitogen-activated protein kinase
Mcl-1
myeloid leukemia cell differentiation protein
MDM2
murine double minute 2
MDR
multidrug resistance
MKP
MAPK phosphatase
MRP1
multidrug resistance protein 1
NF-κB
nuclear factor-kappaB
pAkt
phosphor-Akt
PARP
poly ADP-ribose polymerase
P-gp
P-glycoprotein
PI3K-PTEN
phosphatidylinositol 3-kinase-phosphatase and tensin homolog
PKC
phosphorylated at Ser9 by protein kinase C
pp2A
protein phosphatase 2A
REST
repressor element-1 silencing transcription factor
SAR
structure-activity relationship
TAM
tumor-associated macrophage
TFIIH
transcription factor IIH
TKI
tyrosine kinase inhibitor
TM
tumor-microenvironment
TRAIL/Apo-2L
TNF-related apoptosis-inducing ligand
tRXRα
the N-terminal truncated form of the nuclear retinoid X receptor-α
TWHF
Tripterygium wilfordii Hook F
VEGF
vascular endothelial growth factor
XIAP
X-linked IAP
XPB
xerodermapigmentosum group B protein
Triptolide
Antineoplastic
Resistance
Sensitization
Mechanism
Probucol ameliorates renal injury in diabetic nephropathy by inhibiting the expression of the redox enzyme p66Shc
期刊论文
Redox Biology, 2017, 卷号: 13, 页码: 482-497
作者:
Yang, Shikun
;
Zhao, Li
;
Han, Yachun
;
Liu, Yu
;
Chen, Chao
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2019/12/03
DN
diabetic nephropathy
ROS
reactive oxygen species
HG
high-glucose
SIRT1
sirtuin-1
Ac-H3
acetyl-histone H3
STZ
streptozotocin
AMPK
AMP-activated protein kinase
ECM
extracellular matrix
Nox2
NADPH oxidase 2
EMT
tubular epithelial-mesenchymal transition
DAPI
4′,6-diamidino-2-phenylindole 9
DHE
dihydroethidium
NDRD
non-diabetic renal disease
H&E
hematoxylin-eosin
PAS
periodic acid-Schiff
PASM
periodic acid-silver methenamine
IHC
immunohistochemistry
MDA
malondialdehyde
ChIP
chromatin immunoprecipitation
TC
total cholesterol
BUN
blood urea nitrogen
FN
fibronectin
HBA1C
glycosylated hemoglobin
Scr
serum creatinine
TG
triglyceride
Probucol
Renal injury
Diabetic nephropathy
p66Shc
Role of C/EBP homologous protein and endoplasmic reticulum stress in asthma exacerbation by regulating the IL-4/signal transducer and activator of transcription 6/transcription factor EC/IL-4 receptor α positive feedback loop in M2 macrophages
期刊论文
Journal of Allergy and Clinical Immunology, 2017, 卷号: 140, 期号: 6, 页码: 1550-1561.e8
作者:
Wang, Yi
;
Zhu, Jianghui
;
Zhang, Lei
;
Zhang, Zhijun
;
He, Long
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/03
C/EBP homologous protein
asthma
macrophage
endoplasmic reticulum stress
AHR
Airway hyperresponsiveness
Atf4
Activating transcription factor 4
BALF
Bronchoalveolar lavage fluid
Bip
Binding immunoglobulin protein
ChIP
Chromatin immunoprecipitation
Chop
C/EBP homologous protein
eIF2α
Eukaryotic initiation factor 2α
ER
Endoplasmic reticulum
Fizz1
Found in inflammatory zone 1
IL-4Rα
IL-4 receptor α
OVA
Ovalbumin
PEF
Peak expiratory flow
Rn
Lung resistance
shRNA
Short hairpin RNA
STAT6
Signal transducer and activator of transcription 6
Tfec
Transcription factor EC
WT
Wild-type
Salt-inducible Kinase (SIK1) regulates HCC progression and WNT/β-catenin activation
期刊论文
Journal of Hepatology, 2016, 卷号: 64, 期号: 5, 页码: 1076-1089
作者:
Qu, Chao
;
He, De
;
Lu, Xiaoling
;
Dong, Lihua
;
Zhu, Yuekun
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2019/12/03
ChIP
chromatin immunoprecipitation
DFS
disease-free survival
EGF
epidermal growth factor
EMT
epithelial-mesenchymal transition
GSK-3β
glycogen synthase kinase-3β
HCC
hepatocellular carcinoma
HDAC3
histone deacetylase 3
IF
immunofluorescence
IHC
immunohistochemistry
NCoR
nuclear receptor corepressor
OS
overall survival
PCR
polymerase chain reaction
TBL1
transducin-beta-like protein 1
TBLR1
transducing-beta-like 1 X-linked receptor 1
TF
transcriptional factor
shSIK1
small hairpin RNA targeting SIK1
Salt-inducible kinase 1
Twist1
Epithelial-mesenchymal transition
β-catenin
Silencing mediator for retinoid
Thyroid receptors
A novel function of nuclear nonmuscle myosin regulatory light chain in promotion of xanthine oxidase transcription after myocardial ischemia/reperfusion
期刊论文
Free Radical Biology and Medicine, 2015, 卷号: 83, 页码: 115-128
作者:
Zhang, Yi-Shuai
;
Liu, Bin
;
Luo, Xiu-Ju
;
Zhang, Jie-Jie
;
Li, Nian-Sheng
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2019/12/03
XO
xanthine oxidase
MLC20
myosin regulatory light chain
smMLC20
smooth muscle MLC20
nmMLC20
nonmuscle MLC20
MYL2
cardiac muscle MLC20
MLCK
myosin light chain kinase
co-IP
coimmunoprecipitation
ChIP
chromatin immunoprecipitation
ROS
reactive oxygen species
IR
ischemia/reperfusion
HR
hypoxia/reoxygenation
TUNEL
terminal deoxynucleotidyl transferase-mediated dUTP nick-end labeling
ICAM-1
intercellular adhesion molecule-1
siRNA
small interfering RNA
MUT
mutant
WT
wild type
GAPDH
glyceraldehyde-3-phosphate dehydrogenase.
Nonmuscle myosin regulatory light chain
Ischemia
Reperfusion
Xanthine oxidase
Transcription
Free radicals
Promyelocytic leukemia protein induces arsenic trioxide resistance through regulation of aldehyde dehydrogenase 3 family member A1 in hepatocellular carcinoma
期刊论文
Cancer Letters, 2015, 卷号: 366, 期号: 1, 页码: 112-122
作者:
Zhang, Xin
;
Yang, Xin-Rong
;
Sun, Chao
;
Hu, Bo
;
Sun, Yun-Fan
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/12/03
HCC
hepatocellular carcinoma
ATO
arsenic trioxide
APL
acute promyelocytic leukemia
PML
promyelocytic leukemia protein
RARα
retinoic acid receptor α
ALDH3A1
aldehyde dehydrogenase 3 family member A1
qRT-PCR
quantitative real-time reverse transcriptase polymerase chain reaction
TMA
tissue microarray
OS
overall survival
TTR
time to recurrence
DMEM
Dulbecco's modified Eagle's medium
CB7
1-[(4-fluorophenyl) sulfonyl]-2-methyl-1H-benzimidazole
siRNA
small interfering RNA
shRNA
small hairpin RNA
GFP
green fluorescent protein
MTT
3-(4,5-dimethylthiazol2-yl)-2,5-diphenyltetrazolium bromide
ChIP
chromatin immunoprecipitation
ORF
open reading frame
ROS
reactive oxygen species
DCFH-DA
2,7-dichlorfluorescein-diacetate
AFP
α-fetoprotein
ALT
alanine aminotransferase
TTP
time to progression
GO
gene ontology
NFκB
nuclear factor kappa-light-chain-enhancer of activated B cells
Bcl-2
B-cell lymphoma 2
Promyelocytic leukemia protein
Aldehyde dehydrogenase 3 family member A1
Reactive oxygen species
Tumor growth
Drug resistance
CBP-dependent Wnt/beta-catenin Signaling is Crucial in Regulation of MDR1 Transcription
期刊论文
Current Cancer Drug Targets, 2015, 卷号: 15, 期号: 6, 页码: 519-532
作者:
Xia, Zanxian*
;
Guo, Mingquan
;
Liu, Han
;
Jiang, Luwei
;
Li, Qiaoxia
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2019/12/03
CBP
Chromatin Immunoprecipitation
MDR1
p300
RNAi
Wnt/beta-catenin
As a novel p53 direct target, bidirectional gene HspB2/αB-crystallin regulates the ROS level and Warburg effect
期刊论文
Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, 2014, 卷号: 1839, 期号: 7, 页码: 592-603
作者:
Liu, Shuang
;
Yan, Bin
;
Lai, Weiwei
;
Chen, Ling
;
Xiao, Desheng
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/12/03
αBC
αB-crystallin
ActD
Actinomycin D
ChIP
chromatin immunoprecipitation
EMSA
Electrophoretic Mobility Shift
HK2
hexokinase II
HspB2
heat shock protein B2
RCC
renal cell carcinoma
ROS
reactive oxygen species
SCO2
cytochrome c oxidase 2
sHSPs
small heat shock proteins
TIGAR
TP53-induced glycolysis and apoptosis regulator
Bidirectional promoter
p53
HspB2
αB-crystallin
Warburg effect
Renal cell carcinoma
Curcumin Alleviates Neuropathic Pain by Inhibiting p300/CBP Histone Acetyltransferase Activity-Regulated Expression of BDNF and Cox-2 in a Rat Model
期刊论文
PLOS ONE, 2014, 卷号: 9, 期号: 3, 页码: e91303
作者:
Zhu, Xiaoyan
;
Li, Qian
;
Chang, Ruimin
;
Yang, Dong
;
Song, Zongbing
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/03
Neuropathic pain,Histones,Gene expression,Allodynia,Chromatin immunoprecipitation,DNA transcription,Hyperalgesia,Spinal cord
Identification of target genes of transcription factor CEBPB in acute promyelocytic leukemia cells induced by all-trans retinoic acid
期刊论文
Asian Pacific Journal of Tropical Medicine, 2013, 卷号: 6, 期号: 6, 页码: 473-480
作者:
Yu, Lei
;
Zhang, Yang-De
;
Zhou, Jun
;
Yao, De-Ming
;
Li, Xiang*
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/03
Chromatin immunoprecipitation
All-trans retinoic acid
CEBP
Granulopoiesis
Neutrophils
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