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上海药物研究所 [16]

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期刊论文 [16]

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限定条件	专题：上海药物研究所第一署名单位第一作者单位通讯作者单位

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	Preferential Targeting Cerebral Ischemic Lesions with Cancer Cell-Inspired Nanovehicle for Ischemic Stroke Treatment 期刊论文 NANO LETTERS, 2021, 卷号: 21, 期号: 7, 页码: 3033-3043 作者: He, Wenxiu; Mei, Qiyong; Li, Jie; Zhai, Yuting; Chen, Yiting 收藏 \| 浏览/下载：44/0 \| 提交时间：2021/06/11 ischemic stroke blood-brain barrier bioinspired nanovehicle cell membrane drug delivery
	A proton-coupled organic cation antiporter is involved in the blood-brain barrier transport of Aconitum alkaloids 期刊论文 JOURNAL OF ETHNOPHARMACOLOGY, 2020, 卷号: 252, 页码: 9 作者: Cong, Jiaojiao; Ruan, Yiling; Lyu, Qinglin; Qin, Xiaohui; Qi, Xinming 收藏 \| 浏览/下载：28/0 \| 提交时间：2020/07/01 Aconitum alkaloids Blood-brain barrier Proton-coupled organic cation antiporter hCMEC/D3 cells Drug transport
	Repurposing antimycotic ciclopirox olamine as a promising anti-ischemic stroke agent 期刊论文 ACTA PHARMACEUTICA SINICA B, 2020, 卷号: 10, 期号: 3, 页码: 434-446 作者: Feng, Hongxuan; Hu, Linghao; Zhu, Hongwen; Tao, Lingxue; Wu, Lei 收藏 \| 浏览/下载：29/0 \| 提交时间：2020/07/01 Blood-brain barrier Brain ischemia Cell cycle Inflammation Neuroprotection
	currenttrendsindrugmetabolismandpharmacokinetics 期刊论文 actapharmaceuticasinicab, 2019, 卷号: 9, 期号: 6, 页码: 1113 作者: Liu Dongyang; Hou Xiangyu; Tang Lan; Wang Xin; Lyu Yuanfeng 收藏 \| 浏览/下载：20/0 \| 提交时间：2020/07/01 ARYL-HYDROCARBON RECEPTOR BLOOD-BRAIN-BARRIER ORGANIC ANION TRANSPORTERS CHRONIC KIDNEY-DISEASE PREGNANE-X-RECEPTOR P-GLYCOPROTEIN QUANTITATIVE PREDICTION CYTOCHROME-P450 ENZYMES DOWN-REGULATION IN-VIVO Pharmacokinetics Drug metabolism Drug-drug interactions Modeling Metabolizing enzymes Transporters Nuclear receptors Noncoding RNAs
	amyloidbetastructurebiologyandstructurebasedtherapeuticdevelopment 期刊论文 actapharmacologicasinica, 2017, 卷号: 38, 期号: 9, 页码: 1205 作者: Chen Guofang; Xu Tinghai; Yan Yan; Zhou Yuren; Jiang Yi 收藏 \| 浏览/下载：49/0 \| 提交时间：2020/07/01 BLOOD-BRAIN-BARRIER INSULIN-DEGRADING ENZYME SOLID-STATE NMR NICOTINIC ACETYLCHOLINE-RECEPTORS METABOTROPIC GLUTAMATE RECEPTORS ATOMIC-FORCE MICROSCOPY GAMMA-SECRETASE COMPLEX SMOOTH-MUSCLE-CELLS AMELIORATES MEMORY IMPAIRMENT ENDOTHELIN-CONVERTING ENZYME amyloid beta peptide amyloid precursor protein Alzheimer's disease neurodegenerative diseases drug discovery
	Nose-to-brain delivery of macromolecules mediated by cell-penetrating peptides 期刊论文 ACTA PHARMACEUTICA SINICA B, 2016, 卷号: 6, 期号: 4, 页码: 352-358 作者: Lin, Tingting; Liu, Ergang; He, Huining; Shin, Meong Cheol; Moon, Cheol 收藏 \| 浏览/下载：27/0 \| 提交时间：2019/01/08 Intranasal protein delivery Brain targeting Cell-penetrating peptide Low molecular weigh protamine Blood brain barrier
	. Isomer-selective distribution of 3-n-butylphthalide (NBP) hydroxylated metabolites, 3-hydroxy-NBP and 10-hydroxy-NBP, across the rat blood-brain barrier 期刊论文 ACTA PHARMACOLOGICA SINICA, 2015, 卷号: 36, 期号: 12, 页码: 1520-1527 作者: Diao, Xing-xing; Zhong, Kan; Li, Xiu-li; Zhong, Da-fang; Chen, Xiao-yan 收藏 \| 浏览/下载：24/0 \| 提交时间：2019/01/08 3-n-butylphthalide (NBP) 3-OH-NBP 10-OH-NBP blood-brain barrier isomer-selective drug plasma protein binding drug brain protein binding P-gp/BCRP cerebral ischemia
	isomerselectivedistributionof3nbutylphthalidenbphydroxylatedmetabolites3hydroxynbpand10hydroxynbpacrosstheratbloodbrainbarrier 期刊论文 actapharmacologicasinica, 2015, 卷号: 36, 期号: 12, 页码: 1520 作者: Diao Xingxing; Zhong Kan; Li Xiuli; Zhong Dafang; Chen Xiaoyan 收藏 \| 浏览/下载：13/0 \| 提交时间：2020/07/01 CANCER RESISTANCE PROTEIN P-GLYCOPROTEIN P-GP/ABCB1 TANDEM MASS-SPECTROMETRY FOCAL CEREBRAL-ISCHEMIA PLASMA-PROTEIN CHIRAL 3-N-BUTYLPHTHALIDE TISSUE DISTRIBUTION DRUG DISCOVERY BINDING PENETRATION 3-n-butylphthalide (NBP) 3-OH-NBP 10-OH-NBP blood-brain barrier isomer-selective drug plasma protein binding drug brain protein binding P-gp/BCRP cerebral ischemia
	Lead compound optimization strategy (4) improving blood-brain barrier permeability through structural modification 期刊论文 Acta Pharmaceutica Sinica, 2014, 卷号: 49, 期号: 6, 页码: 789-799 作者: Hong Yu; Zhou Yu; Wang Jiang; Liu Hong 收藏 \| 浏览/下载：18/0 \| 提交时间：2019/01/08 blood-brain barrier structure optimization drug design central nervous system
	P-glycoprotein and multidrug resistance-associated protein 2 are oppositely altered in brain of rats with thioacetamide-induced acute liver failure 期刊论文 LIVER INTERNATIONAL, 2013, 卷号: 33, 期号: 2, 页码: 274-282 作者: Jin, Shi; Wang, Xin-Ting; Liu, Li; Yao, Dan; Liu, Can 收藏 \| 浏览/下载：15/0 \| 提交时间：2019/01/08 Acute liver failure Brain-blood barrier multidrug resistance-associated protein 2 P-glycoprotein

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