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科研机构
上海药物研究所 [9]
内容类型
期刊论文 [9]
发表日期
2020 [2]
2019 [2]
2018 [3]
2014 [1]
2005 [1]
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23,24-Dihydrocucurbitacin B promotes lipid clearance by dual transcriptional regulation of LDLR and PCSK9
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 卷号: 41, 期号: 3, 页码: 327-335
作者:
Li, Hui-hui
;
Li, Jun
;
Zhang, Xian-jing
;
Li, Jiao-meng
;
Xi, Cong
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2020/07/01
23,24-dihydrocucurbitacin B
lipid-lowering agent
LDLR
PCSK9
HNF1 alpha
SREBP2
2324dihydrocucurbitacinbpromoteslipidclearancebydualtranscriptionalregulationofldlrandpcsk9
期刊论文
actapharmacologicasinica, 2020, 卷号: 41, 期号: 3, 页码: 327
作者:
Li Huihui
;
Li Jun
;
Zhang Xianjing
;
Li Jiaomeng
;
Xi Cong
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2020/07/01
23
24-dihydrocucurbitacin B
lipid-lowering agent
LDLR
PCSK9
HNF1α
SREBP2
Design, synthesis, and biological evaluation of novel tetrahydroprotoberberine derivatives (THPBs) as proprotein convertase subtilisin/kexin type 9 (PCSK9) modulators for the treatment of hyperlipidemia
期刊论文
ACTA PHARMACEUTICA SINICA B, 2019, 卷号: 9, 期号: 6, 页码: 1216-1230
作者:
Wu, Chenglin
;
Xi, Cong
;
Tong, Junhua
;
Zhao, Jing
;
Jiang, Hualiang
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2020/07/01
PCSK9
Tetrahydroprotoberberine derivatives
Low-density lipoprotein cholesterol
Lipid-lowering
PCSK9 expression
Low-density lipoprotein receptor
Total cholesterol
Hyperlipidemia hamster
designsynthesisandbiologicalevaluationofnoveltetrahydroprotoberberinederivativesthpbsasproproteinconvertasesubtilisinkexintype9pcsk9modulatorsforthetreatmentofhyperlipidemia
期刊论文
actapharmaceuticasinicab, 2019, 卷号: 9, 期号: 6, 页码: 1216
作者:
Wu Chenglin
;
Xi Cong
;
Tong Junhua
;
Zhao Jing
;
Jiang Hualiang
收藏
  |  
浏览/下载:52/0
  |  
提交时间:2020/07/01
DOPAMINE D-1
BERBERINE
EXPRESSION
INHIBITORS
IDENTIFICATION
CHOLESTEROL
MUTATIONS
LDLR
PCSK9
Tetrahydroprotoberberine derivatives
Low-density lipoprotein cholesterol
Lipid-lowering
PCSK9 expression
Low-density lipoprotein receptor
Total cholesterol
Hyperlipidemia hamster
Proteomics analysis reveals a potential new target protein for the lipid-lowering effect of Berberine8998
期刊论文
ACTA PHARMACOLOGICA SINICA, 2018, 卷号: 39, 期号: 9, 页码: 1473-1482
作者:
Yu, Cheng-yin
;
Liu, Gang-yi
;
Liu, Xiao-hui
;
Gui, Yu-zhou
;
Liu, Hai-ming
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2019/01/08
berberine
berberine8998
proteomics
lipid-lowering
cholesterol
triglycerides
LDL-C
fatty acid metabolism
hypercholesterolemia
obesity
Jatrophane diterpenoids from Euphorbia helioscopia and their lipid-lowering activities
期刊论文
FITOTERAPIA, 2018, 卷号: 128, 页码: 102-111
作者:
Li, Jun
;
Li, Hui-hui
;
Wang, Wen-qiong
;
Song, Wei-bin
;
Wang, Yi-ping
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2019/01/08
Euphorbia helioscopia
Jatrophanes
Hyperlipidemia
Lipid-lowering
LDL receptor
proteomicsanalysisrevealsapotentialnewtargetproteinforthelipidloweringeffectofberberine8998
期刊论文
actapharmacologicasinica, 2018, 卷号: 39, 期号: 9, 页码: 1473
作者:
u Chengyin
;
Liu Gangyi
;
Liu Xiaohui
;
Gui Yuzhou
;
Liu Haiming
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2020/07/01
DISEASE
ATHEROSCLEROSIS
IDENTIFICATION
CHALLENGES
EFFICACY
RECEPTOR
berberine
berberine8998
proteomics
lipid-lowering
cholesterol
triglycerides
LDL-C
fatty acid metabolism
hypercholesterolemia
obesity
Alkaloids from lotus leaf and related bioactivities
期刊论文
Chinese Traditional Patent Medicine, 2014, 卷号: 36, 期号: 11, 页码: 2330-2333
作者:
Yuan Pulong
;
Chen Liang
;
Liu Xiaoyu
;
Yu Bangwei
;
Haung Qi
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2019/01/08
lotus leaf(Nelumbo nucifera)
alkaloids
2-hydroxy-l-methoxyaporphine
antibacterial
lipid-lowering
hypoglycemic
Current status of studies on Acyl-CoA: Cholesterol Acyltransferase (ACAT) inhibitors
期刊论文
Chinese Journal New Drugs, 2005, 卷号: 14, 期号: 4, 页码: 396-400
作者:
Din Derong
;
Shen Jingkang
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/01/08
ACAT inhibitor
atherosclerosis
cholesterol-lowering
lipid-lowering
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