CORC

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CORC

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Synthesis and Evaluation of 3-(Indol-3-yl)-4-(Pyrazolo[3,4-c]Pyridazin-3-yl)-Maleimides as Potent Mutant Isocitrate Dehydrogenase-1 Inhibitors 期刊论文
PHARMACEUTICAL CHEMISTRY JOURNAL, 2021, 卷号: 55, 期号: 7, 页码: 655-664
作者:  Xu, Jianghong;  Hu, Yuanyuan;  Liu, Xiaoqi;  Gao, Anhui;  Gao, Lixin
收藏  |  浏览/下载：37/0  |  提交时间：2021/12/01
Reprogramming the immunosuppressive microenvironment of IDH1 wild-type glioblastoma by blocking Wnt signaling between microglia and cancer cells 期刊论文
ONCOIMMUNOLOGY, 2021, 卷号: 10, 期号: 1, 页码: 13
作者:  Fan, Dandan;  Yue, Qi;  Chen, Jian;  Wang, Cong;  Yu, Ruilin
收藏  |  浏览/下载：25/0  |  提交时间：2021/08/17
Discovery of Novel IDH1 Inhibitor Through Comparative Structure-Based Virtual Screening 期刊论文
FRONTIERS IN PHARMACOLOGY, 2020, 卷号: 11, 页码: 11
作者:  Wang, Yuwei;  Tang, Shuai;  Lai, Huanling;  Jin, Ruyi;  Long, Xu
收藏  |  浏览/下载：53/0  |  提交时间：2020/12/24
Licochalcone A suppresses the proliferation of sarcoma HT-1080 cells, as a selective R132C mutant IDH1 inhibitor 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 2, 页码: 5
作者:  Hu, Chujiao;  Zuo, Yu;  Liu, Jingqiu;  Xu, Heng;  Liao, Weike
收藏  |  浏览/下载：41/0  |  提交时间：2020/07/01
Pharmacological characterization of TQ05310, a potent inhibitor of isocitrate dehydrogenase 2 R140Q and R172K mutants 期刊论文
CANCER SCIENCE, 2019, 页码: 9
作者:  Gao, Mingzhao;  Zhu, Hongmei;  Fu, Li;  Li, Yun;  Bao, Xubin
收藏  |  浏览/下载：19/0  |  提交时间：2020/07/01
AG-221  IDH2  leukemia  R140Q  R172K  
Discovery of DC_H31 as potential mutant IDH1 inhibitor through NADPH-based high throughput screening 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2019, 卷号: 27, 期号: 15, 页码: 3229-3236
作者:  Duan, Zhe;  Liu, Jingqiu;  Niu, Liping;  Wang, Jun;  Feng, Mingqian
收藏  |  浏览/下载：57/0  |  提交时间：2020/07/01
Synthesis and biological evaluation of 3-aryl-4-indolyl-maleimides as potent mutant isocitrate dehydrogenase-1 inhibitors 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2019, 卷号: 27, 期号: 4, 页码: 589-603
作者:  Liu, Xiaoqi;  Hu, Yuanyuan;  Gao, Anhui;  Xu, Meng;  Gao, Lixin
收藏  |  浏览/下载：31/0  |  提交时间：2020/07/01
Discovery and structure-activity-relationship study of novel imidazole cyclopropyl amine analogues for mutant isocitric dehydrogenase 1 (IDH1) inhibitors 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2018, 卷号: 28, 期号: 23-24, 页码: 3808-3812
作者:  Zheng, Qiangang;  Chen, Ziqi;  Wan, Huixin;  Tang, Shuai;  Ye, Yan
收藏  |  浏览/下载：236/0  |  提交时间：2019/01/08
Discovery and structure-activity-relationship study of novel conformationally restricted indane analogues for mutant isocitric dehydrogenase 1 (IDH1) inhibitors 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2017, 卷号: 27, 期号: 23, 页码: 5262-5266
作者:  Zheng, Qiangang;  Tang, Shuai;  Fu, Xianlei;  Chen, Ziqi;  Ye, Yan
收藏  |  浏览/下载：34/0  |  提交时间：2019/01/08
异柠檬酸脱氢酶(IDH1与IDH2)突变促进肿瘤生成的机制探索 会议论文
作者:  高明钊;  楼丽广
收藏  |  浏览/下载：17/0  |  提交时间：2019/01/08

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