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科研机构
上海药物研究所 [26]
内容类型
期刊论文 [26]
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2021 [4]
2020 [4]
2019 [6]
2018 [3]
2017 [3]
2016 [1]
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Discovery of novel ceramide analogs with favorable pharmacokinetic properties and combination with AKT inhibitor against colon cancer
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 215, 页码: 13
作者:
Gao, Feng
;
Chen, Xiaoxu
;
Lu, Junyan
;
Hu, Shulei
;
Xu, Hui
收藏
  |  
浏览/下载:45/0
  |  
提交时间:2021/05/24
Ceramide analogs
AKT inhibitor
MK2206
Colon cancer
Combination therapy
SAF-248, a novel PI3K delta-selective inhibitor, potently suppresses the growth of diffuse large B-cell lymphoma
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 11
作者:
Zhang, Xi
;
Duan, Yu-ting
;
Wang, Yi
;
Zhao, Xing-dong
;
Sun, Yi-ming
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2021/05/24
PI3Kδ
PI3K
AKT
mTOR
diffuse large B-cell lymphoma
resistance
combination therapy
Biomimetic codelivery overcomes osimertinib-resistant NSCLC and brain metastasis via macrophage-mediated innate immunity
期刊论文
JOURNAL OF CONTROLLED RELEASE, 2021, 卷号: 329, 页码: 1249-1261
作者:
Zhao, Pengfei
;
Zhang, Jiaxin
;
Wu, Aihua
;
Zhang, Meng
;
Zhao, Yuge
收藏
  |  
浏览/下载:109/0
  |  
提交时间:2021/05/24
Brain targeting delivery
Tumor-associated macrophage
Osimertinib resistance
Brain metastasis
Innate immunity
Combination therapy
Allosteric Inhibitors of SHP2: An Updated Patent Review (2015-2020)
期刊论文
CURRENT MEDICINAL CHEMISTRY, 2021, 卷号: 28, 期号: 19, 页码: 3825-3842
作者:
Wu, Jingwei
;
Zhang, Huan
;
Zhao, Guilong
;
Wang, Runling
收藏
  |  
浏览/下载:65/0
  |  
提交时间:2021/08/17
SHP2 inhibitor
PTPN11 gene
allosteric
cancer
combination therapy
clinical trial
Cancer nanomedicine meets immunotherapy: opportunities and challenges
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 卷号: 41, 期号: 7, 页码: 954-958
作者:
Sun, Qingxue
;
Bai, Xiangyang
;
Sofias, Alexandros Marios
;
van der Meel, Roy
;
Ruiz-Hernandez, Eduardo
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2020/12/24
nanomedicine
immunotherapy
targeting
combination therapy
clinical translation
Supramolecular Drug-Drug Complex Vesicles Enable Sequential Drug Release for Enhanced Combination Therapy
期刊论文
ACS APPLIED MATERIALS & INTERFACES, 2020, 卷号: 12, 期号: 25, 页码: 27940-27950
作者:
Liu, Chengfei
;
Li, Chunpu
;
Pang, Cui
;
Li, Muqiong
;
Li, Huixin
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2020/12/24
drug-drug self-delivery system
supramolecular vesicles
host-guest interaction
self-assembly
pillar[5]arene
combination therapy
Nanotechnology-Based Histone Deacetylase Inhibitors for Cancer Therapy
期刊论文
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 2020, 卷号: 8, 页码: 8
作者:
Tu, Bin
;
Zhang, Meng
;
Liu, Tuanbing
;
Huang, Yongzhuo
收藏
  |  
浏览/下载:68/0
  |  
提交时间:2020/12/24
Histone deacetylase inhibitors (HDACi)
nanotechnology
nanomedicine
cancer therapy
solid tumor
targeting drug delivery
combination therapy
amphiphilicdrugdrugconjugateforcancertherapywithcombinationofchemotherapeuticandantiangiogenesisdrugs
期刊论文
sciencechinachemistry, 2020, 卷号: 63, 期号: 1, 页码: 35
作者:
Sun Mo
;
Qian Qiuhui
;
Shi Leilei
;
Xu Li
;
Liu Qunfang
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2020/07/01
nanoparticle
combination therapy
cancer treatment
supramolecular chemistry
Peptide Nanotube-Templated Biomineralization of Cu2-xS Nanoparticles for Combination Treatment of Metastatic Tumor
期刊论文
SMALL, 2019, 页码: 13
作者:
Lai, Yi
;
Xu, Zhiai
;
Hu, Xianli
;
Lei, Li
;
Li, Lingling
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2020/07/01
biomineralization
cancer metastasis
combination therapy
Fenton reaction
peptide nanotubes
Amphiphilic drug-drug conjugate for cancer therapy with combination of chemotherapeutic and antiangiogenesis drugs
期刊论文
SCIENCE CHINA-CHEMISTRY, 2019, 页码: 7
作者:
Sun, Mo
;
Qian, Qiuhui
;
Shi, Leilei
;
Xu, Li
;
Liu, Qunfang
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2020/07/01
nanoparticle
combination therapy
cancer treatment
supramolecular chemistry
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