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Heat shock protein 70 accelerates atherosclerosis by downregulating the expression of ABCA1 and ABCG1 through the JNK/Elk-1 pathway 期刊论文
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2018, 卷号: 1863, 期号: 8, 页码: 806-822
作者:  Zhao, Zhen-Wang;  Zhang, Min;  Chen, Ling-Yan;  Cong, Duo;  Xia, Xiao-Dan
收藏  |  浏览/下载:4/0  |  提交时间:2019/12/27
Autophagy: A double-edged sword in intervertebral disk degeneration 期刊论文
Clinica chimica acta, international journal of clinical chemistry, 2016, 卷号: 457, 页码: 27-35
作者:  Zhang, Shu-Jun;  Yang, Wei;  Wang, Cheng;  He, Wen-Si;  Deng, Hai-Yang
收藏  |  浏览/下载:16/0  |  提交时间:2019/12/27
IVD  intervertebral disk  NP  nucleus pulposus  AF  annulus fibrosus  CEPs  cartilaginous endplates  ECM  extracellular matrix  Col II  type II collagen  Col I  type I collagen  IDD  intervertebral disk degeneration  LBP  low back pain  miRNAs  microRNAs  ADAMTS  a disintegrin and metalloprotease with thrombospondin motif  MMP  matrix metalloproteinases  HSC70  heat shock cognate protein of 70 kDa  LAMP2A  lysosome-associated membrane protein type-2 A  Atg  autophagy-related genes  ULK  uncoordinated-51-like kinase  PI3KCIII  class III phosphatidylinositol 3-kinase  mTORC1  mammalian target of rapamycin complex 1  DFCP1  double FYVE-containing protein 1  3-MA  3-methyladenine  LC3  microtubule-associated protein 1 light chain 3  PE  phosphatidyl ethanolamine  LAMP-2  lysosomal membrane protein 2  TNF-α  tumor necrosis factor-α  IL-1β  interleukin-1β  NF-κB  nuclear factor-κB  JNK  c-Jun N-terminal kinase  SIRT1  silent mating type information regulator 2 homolog 1  TGF-β1  transforming growth factor-β1  ERK1/2  extracellular signal-regulated kinase 1/2  GRP78  glucose regulated protein 78  H2O2  hydrogen peroxide  Autophagy  IVD  IDD  NP  AF  
MicroRNAs in osteosarcoma 期刊论文
Clinica Chimica Acta, 2015, 卷号: 444, 页码: 9-17
作者:  Zhang, Jian;  Yan, Yi-Guo;  Wang, Cheng;  Zhang, Shu-Jun;  Yu, Xiao-Hua*
收藏  |  浏览/下载:27/0  |  提交时间:2019/12/27
OS  osteosarcoma  miRNAs  microRNAs  CSCs  cancer stem cells  RNA pol  RNA polymerase  DGCR8  DiGeorge syndrome critical gene 8  RISC  RNA-induced silencing complex  Exp 5  exportin 5  Ago  argonaute  MREs  miRNA recognition elements  APE1  apurinic/apyrimidinic endonuclease 1  MDM  murine double minute  TP53  tumor suppressor p53  mTOR  mammalian target of rapamycin  Eag1  ether à go-go 1  PI3K  phosphatidylinositol-3-kinase  PTEN  phosphatase and tensin homolog deleted on chromosome ten  Hsp90B1  heat shock protein 90B1  BMP2  bone morphogenetic protein 2  IGF1R  insulin-like growth factor 1 receptor  FAK  phospho-Akt and focal adhesion kinase  LPAATβ  lysophosphatidic acid acyltransferase β  HMGB1  high-mobility group box 1  FASN  fatty acid synthase  LZTS1  leucine zipper putative tumor suppressor 1  MMP  matrix metalloproteinase  LNA  locked nucleic acid  DATS  diallyl trisulfide  miRNAs  OS  TP53  Notch  Chemoresistance  
Interleukin-17A in lipid metabolism and atherosclerosis 期刊论文
Clinica Chimica Acta, 2014, 卷号: 431, 页码: 33-39
作者:  Yu, Xiao-Hua;  Jiang, Na;  Zheng, Xi-Long;  Cayabyab, Francisco S;  Tang, Zhi-Bin*
收藏  |  浏览/下载:3/0  |  提交时间:2019/12/27
IL-17  interleukin-17  Th17  T helper 17  IL-17R  IL-17 receptor  STAT3  signal transducer and activator of transcription 3  RORγ  retinoic acid receptor-related orphan receptor γ  IRF4  interferon regulatory factor 4  ERK  extracellular signal-regulated kinase  Ets1  E26 transformation-specific 1  15(S)-HETE  15(S)-hydroxyeicosatetraenoic acid  SF1  alternative splicing factor  MAPK  mitogen-activated protein kinase  PPARγ  peroxisome proliferator-activated receptor γ  TRAF  tumor necrosis factor receptor-associated factor  TAK1  transforming growth factor-β-activated kinase 1  TAB  TAK1-binding protein  IKK  IκB kinase  NF-κB  nuclear factor kappa-B  IKKi  inducible IKK  JNK  c-Jun N-terminal kinase  C/EBP  CCAAT/enhancer-binding protein  AP1  activator protein 1  USP  ubiquitin-specific protease  CXCL  CXC chemokine ligand  ASF  alternative splicing factor  Hsp90  heat shock protein 90  RCT  reverse cholesterol transport  ABCA1  ATP-binding cassette transporter A1  apo E  apolipoprotein E  LDLR  low-density lipoprotein receptor  FABP4  fatty acid-binding protein-4  IL-17A  IL-17RA  IL-17RC  Lipid metabolism  Atherosclerosis  
Psychological stress, immune response, and atherosclerosis 期刊论文
Atherosclerosis, 2012, 卷号: 223, 期号: 1, 页码: 69-77
作者:  Gu, Hong-feng*;  Tang, Chao-ke;  Yang, Yong-zong
收藏  |  浏览/下载:11/0  |  提交时间:2019/12/27
Psychological stress  Toll-like 4  NF-κB  Cytokines  Innate immune  Atherosclerosis  HPA  hypothalamic-pituitary-adrenal  SAM  sympathetic-adrenal-medullary  SNS  sympathetic nervous system  Th1, Th2  T helper cell type1, T helper cell type 2  NE  norepinephrine  CRF  corticotropin-releasing factor  POMC  proopiomelanocortin  ACTH  adrenocorticotropic hormone  α-MSH  alpha melanocyte-stimulating hormone  CNS  central nervous system  CRP  C-reactive protein  CD  cluster of differentiation  NK  natural killer  CMV  cytomegalovirus  HSV  herpes simplex virus  VZV  varicella zoster virus  IL-1, IL-4, IL-6, IL-8, IL-10  interleukin-1, interleukin-4, interleukin-6, interleukin-8, interleukin-10  NF-κB  nuclear factor-κB  PBMCs  peripheral blood monocytes  apoE−/− mice  apolipoprotein E knockout mice  LDL  low-density lipoprotein  TLRs, TLR4  Toll-like receptors, Toll-like receptor 4  PRRs  pattern-recognition receptors  SRs  scavenger receptors  oxLDL  oxidized low density lipoprotein  PAMPs  pathogen-associated molecular patterns  PNI  psychoneuroimmunology  GC  glucocorticoid  MR  mineraloreceptor  GR  glucocorticoid receptor  TNF-α  tumor necrosis factor-alpha  LPS  lipopolysaccharide  APPs  acute phase proteins  APR  acute phase response  HSP  heat shock protein  EDA  extra domain A  DAMPs  damage-associated molecular patterns  siRNA  small interfering RNA  MAPKs  mitogen activated protein kinases  MyD88  myeloid differentiation factor-88  TRIF  TIR domain-containing adapter protein inducing IFN-β  ACS  acute coronary syndrome  CHD  coronary heart disease  M-CSF  macrophage-colony-stimulating factor  ICAM-1  intercellular adhesion molecule-1  VCAM-1  vascular cell adhesion molecule-1  MMPs  matrix-degrading matrix metalloproteinases  β-AR  beta-adrenergic receptor  CI  confidence interval  


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