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科研机构
上海中医药大学 [5]
上海药物研究所 [4]
上海大学 [4]
大连化学物理研究所 [3]
大连理工大学 [1]
昆明植物研究所 [1]
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期刊论文 [21]
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2019 [1]
2018 [3]
2017 [5]
2016 [6]
2015 [5]
2013 [1]
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Bavachinin exhibits antitumor activity against non-small cell lung cancer by targeting PPAR gamma
期刊论文
MOLECULAR MEDICINE REPORTS, 2019, 卷号: 20, 期号: 3, 页码: 2805-2811
作者:
Ge, Lu-Na
;
Yan, Lei
;
Li, Cheng
;
Cheng, Kai
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/12/11
bavachinin
A549 cells
lung cancer
peroxisome proliferator-activated
receptor-gamma
reactive oxygen species
Bavachinin analogues as agonists of pan-peroxisome proliferator-activated receptors
期刊论文
MEDICINAL CHEMISTRY RESEARCH, 2018, 卷号: 27, 期号: 7, 页码: 1851-1862
作者:
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2019/01/08
Bavachinin
Metabolic syndrome
PPARs
Reporter gene assaysThese authors contributed equally: Jingyu Yi, Guoxin Du
Bavachinin analogues as agonists of pan-peroxisome proliferator-activated receptors
期刊论文
MEDICINAL CHEMISTRY RESEARCH, 2018, 卷号: 27, 期号: 7
作者:
Yi, Jingyu
;
Du, Guoxin
;
Zhao, Yuanyuan
;
Zhang, Liuqiang
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/05
Bavachinin
Metabolic syndrome
PPARs
Reporter gene assaysThese authors contributed equally: Jingyu Yi, Guoxin Du
Bavachinin Induces Oxidative Damage in HepaRG Cells through p38/JNK MAPK Pathways
期刊论文
2018, 卷号: 10, 期号: 4
作者:
Wang, Shan
;
Wang, Min
;
Tian, Yu
;
Sun, Xiao
;
Sun, Guibo
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2020/01/03
drug-induced liver injury
Bavachinin
reactive oxygen species
p38 MAPK
JNK MAPK
UGT1A10 Is a High Activity and Important Extrahepatic Enzyme: Why Has Its Role in Intestinal Glucuronidation Been Frequently Underestimated?
期刊论文
MOLECULAR PHARMACEUTICS, 2017, 卷号: 14, 期号: 9, 页码: 2875-2883
作者:
Yang, Ling
;
Ge, Guang-Bo
;
Jarvinen, Erkka
;
Troberg, Johanna
;
Finel, Moshe
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2017/12/20
UDP-glucuronosyltransferase
recombinant UGT1A10
intestine microsomes
intestinal glucuronidation
estradiol
estrone
morphine
SN-38
AMC
NCHN
bavachinin
UGT1A10 Is a High Activity and Important Extrahepatic Enzyme: Why Has Its Role in Intestinal Glucuronidation Been Frequently Underestimated?
期刊论文
MOLECULAR PHARMACEUTICS, 2017, 卷号: 14, 期号: 9, 页码: 2875-2883
作者:
Troberg, Johanna
;
Jarvinen, Erkka
;
Ge, Guang-Bo
;
Yang, Ling
;
Finel, Moshe
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2017/12/20
UDP-glucuronosyltransferase
recombinant UGT1A10
intestine microsomes
intestinal glucuronidation
estradiol
estrone
morphine
SN-38
AMC
NCHN
bavachinin
Design, Synthesis, and Structure-Activity Relationships of Bavachinin Analogues as Peroxisome Proliferator-Activated Receptor Agonists
期刊论文
CHEMMEDCHEM, 2017, 卷号: 12, 期号: 2, 页码: 183-193
作者:
Du, Guoxin
;
Zhao, Yuanyuan
;
Feng, Li
;
Yang, Zhuo
;
Shi, Jiye
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2019/01/08
bavachinin
diabetes mellitus
PPAR
reporter gene assays
structure-activity relationships
Design, Synthesis, and Structure-Activity Relationships of Bavachinin Analogues as Peroxisome Proliferator-Activated Receptor Agonists
期刊论文
CHEMMEDCHEM, 2017, 卷号: 12, 期号: 2
作者:
Du, Guoxin
;
Zhao, Yuanyuan
;
Feng, Li
;
Yang, Zhuo
;
Shi, Jiye
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/12/05
bavachinin
diabetes mellitus
PPAR
reporter gene assays
structure-activity relationships
Design, Synthesis, and Structure-Activity Relationships of Bavachinin Analogues as Peroxisome Proliferator-Activated Receptor γ Agonists
期刊论文
ChemMedChem, 2017, 卷号: 12, 页码: 183-193
作者:
Du Guoxin[1]
;
Zhao Yuanyuan[2]
;
Feng Li[3]
;
Yang Zhuo[4]
;
Shi Jiye[5]
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/04/26
PPARγ
bavachinin
diabetes mellitus
reporter gene assays
structure-activity relationships
Bavachinin, as a novel natural pan-PPAR agonist, exhibits unique synergistic effects with synthetic PPAR-gamma and PPAR-alpha agonists on carbohydrate and lipid metabolism in db/db and diet-induced obese mice
期刊论文
DIABETOLOGIA, 2016, 卷号: 59, 期号: 6, 页码: 1276-1286
作者:
Feng, Li
;
Luo, Huan
;
Xu, Zhijian
;
Yang, Zhuo
;
Du, Guoxin
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2016/08/22
Alternative binding site
Bavachinin
Canonical ligand-binding pocket
Carbohydrate metabolism
Lipid metabolism
Pan-PPAR agonist
Synergistic effects
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