×
验证码:
换一张
忘记密码?
记住我
CORC
首页
科研机构
检索
知识图谱
申请加入
托管服务
登录
注册
在结果中检索
科研机构
复旦大学上海医学院 [25]
中国医学科学院 北... [12]
上海药物研究所 [9]
山东大学 [5]
武汉大学 [4]
西安交通大学 [3]
更多...
内容类型
期刊论文 [78]
发表日期
2021 [3]
2020 [2]
2019 [12]
2018 [10]
2017 [14]
2016 [12]
更多...
学科主题
Biochemist... [1]
×
知识图谱
CORC
开始提交
已提交作品
待认领作品
已认领作品
未提交全文
收藏管理
QQ客服
官方微博
反馈留言
浏览/检索结果:
共78条,第1-10条
帮助
限定条件
内容类型:期刊论文
已选(
0
)
清除
条数/页:
5
10
15
20
25
30
35
40
45
50
55
60
65
70
75
80
85
90
95
100
排序方式:
请选择
作者升序
作者降序
题名升序
题名降序
发表日期升序
发表日期降序
提交时间升序
提交时间降序
Synthesis and Evaluation of 3-(Indol-3-yl)-4-(Pyrazolo[3,4-c]Pyridazin-3-yl)-Maleimides as Potent Mutant Isocitrate Dehydrogenase-1 Inhibitors
期刊论文
PHARMACEUTICAL CHEMISTRY JOURNAL, 2021, 卷号: 55, 期号: 7, 页码: 655-664
作者:
Xu, Jianghong
;
Hu, Yuanyuan
;
Liu, Xiaoqi
;
Gao, Anhui
;
Gao, Lixin
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2021/12/01
IDH1-R132H inhibitors
synthesis
biological activity
docking
3-(indol-3-yl)-4-(pyrazolo-[3
4-c]pyridazin-3-yl)-maleimides
Reprogramming the immunosuppressive microenvironment of IDH1 wild-type glioblastoma by blocking Wnt signaling between microglia and cancer cells
期刊论文
ONCOIMMUNOLOGY, 2021, 卷号: 10, 期号: 1, 页码: 13
作者:
Fan, Dandan
;
Yue, Qi
;
Chen, Jian
;
Wang, Cong
;
Yu, Ruilin
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2021/08/17
Wnt/beta-catenin
IDH1-wildtype glioblastoma
Microglia
Phenotypic polarization
Isocitrate Dehydrogenase 2 Inhibitors for the Treatment of Hematologic Malignancies: Advances and Future Opportunities
期刊论文
MINI-REVIEWS IN MEDICINAL CHEMISTRY, 2021, 卷号: 21
作者:
Huang, Feng
;
Tian, Tian
;
Wu, Yizhe
;
Che, Jinxin
;
Yang, Haiyan
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2021/06/15
Isocitrate dehydrogenase 2
IDH2
mutant
inhibitors
structure-activity relationship
blood cance
Discovery of Novel IDH1 Inhibitor Through Comparative Structure-Based Virtual Screening
期刊论文
FRONTIERS IN PHARMACOLOGY, 2020, 卷号: 11, 页码: 11
作者:
Wang, Yuwei
;
Tang, Shuai
;
Lai, Huanling
;
Jin, Ruyi
;
Long, Xu
收藏
  |  
浏览/下载:53/0
  |  
提交时间:2020/12/24
IDH1
gliomas
molecular docking
virtual screening
docking-based virtual screening
Licochalcone A suppresses the proliferation of sarcoma HT-1080 cells, as a selective R132C mutant IDH1 inhibitor
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 2, 页码: 5
作者:
Hu, Chujiao
;
Zuo, Yu
;
Liu, Jingqiu
;
Xu, Heng
;
Liao, Weike
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2020/07/01
Licochalcone A
Mutant IDH1
Selective inhibitor
Pharmacological characterization of TQ05310, a potent inhibitor of isocitrate dehydrogenase 2 R140Q and R172K mutants
期刊论文
CANCER SCIENCE, 2019, 页码: 9
作者:
Gao, Mingzhao
;
Zhu, Hongmei
;
Fu, Li
;
Li, Yun
;
Bao, Xubin
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2020/07/01
AG-221
IDH2
leukemia
R140Q
R172K
Discovery of DC_H31 as potential mutant IDH1 inhibitor through NADPH-based high throughput screening
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2019, 卷号: 27, 期号: 15, 页码: 3229-3236
作者:
Duan, Zhe
;
Liu, Jingqiu
;
Niu, Liping
;
Wang, Jun
;
Feng, Mingqian
收藏
  |  
浏览/下载:57/0
  |  
提交时间:2020/07/01
IDH1 mutation
High-throughput screening
Pan-inhibitor
2-HG
Gliomas
Integrated Metabolomics and Lipidomics Analyses Reveal Metabolic Reprogramming in Human Glioma with IDH1 Mutation
期刊论文
JOURNAL OF PROTEOME RESEARCH, 2019, 卷号: 18, 期号: 3, 页码: 960-969
作者:
Xu, Guowang
;
Zhou, Lina
;
Wang, Zhichao
;
Hu, Chunxiu
;
Zhang, Chaoqi
收藏
  |  
浏览/下载:80/0
  |  
提交时间:2019/06/20
glioma
IDH1
metabolomics
lipidomics
metabolic reprogramming
Integrated metabolomics and lipidomics analyses reveal metabolic reprogramming in human glioma with idh1 mutation
期刊论文
Journal of proteome research, 2019, 卷号: 18, 期号: 3, 页码: 960-969
作者:
Zhou, Lina
;
Wang, Zhichao
;
Hu, Chunxiu
;
Zhang, Chaoqi
;
Kovatcheva-Datchary, Petia
收藏
  |  
浏览/下载:94/0
  |  
提交时间:2019/05/08
Glioma
Idh1
Metabolomics
Lipidomics
Metabolic reprogramming
Synthesis and biological evaluation of 3-aryl-4-indolyl-maleimides as potent mutant isocitrate dehydrogenase-1 inhibitors
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2019, 卷号: 27, 期号: 4, 页码: 589-603
作者:
Liu, Xiaoqi
;
Hu, Yuanyuan
;
Gao, Anhui
;
Xu, Meng
;
Gao, Lixin
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2020/07/01
3-Aryl-4-indolyl-maleimides
IDH1/R132H inhibitors
Tumor 2-HG
Synthesis
©版权所有 ©2017 CSpace - Powered by
CSpace