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科研机构
复旦大学上海医学院 [3]
中国医学科学院 北京... [3]
上海药物研究所 [2]
中南大学 [2]
中国水产科学院 [2]
武汉大学 [2]
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内容类型
期刊论文 [19]
发表日期
2018 [19]
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Discovery of FS36 as a Novel Human Hsp90 Inhibitor
期刊论文
PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS, 2018, 卷号: 45, 期号: 7, 页码: 736-744
作者:
Li Gen
;
Lu Kai-Kai
;
Li Jian
;
Yin Xiu-Shan
;
Zhao Dong
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2019/01/08
heat shock protein 90
antitumor drugs
inhibitor
X-ray diffraction
complex crystal structure
Design, synthesis and pharmacological evaluation of ALK and Hsp90 dual inhibitors bearing resorcinol and 2,4-diaminopyrimidine motifs
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 152, 页码: 76-86
作者:
Geng, Kaijun
;
Liu, Hongchun
;
Song, Zilan
;
Zhang, Chi
;
Zhang, Minmin
收藏
  |  
浏览/下载:181/0
  |  
提交时间:2019/01/08
Heat shock protein 90 (Hsp90)
Tyrosine kinase ALK
Dual inhibitor
Drug resistance
Antiproliferative activity
HSPA12B overexpression induces cisplatin resistance in non-small-cell lung cancer by regulating the PI3K/Akt/NF-kappa B signaling pathway
期刊论文
ONCOLOGY LETTERS, 2018, 卷号: 15, 期号: 3
作者:
Chen, Wei
;
Liu, Xiaoqun
;
Yuan, Sujuan
;
Qiao, Tiankui
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/12/05
non-small cell lung cancer
heat shock protein family A member 12B
cisplatin
phosphoinositide 3-kinase/protein kinase B/nuclear factor-kappa B signaling pathway
Icariin protects against ischemia-reperfusion injury in H9C2 cells by upregulating heat shock protein 20
期刊论文
MOLECULAR MEDICINE REPORTS, 2018, 卷号: 17, 期号: 2
作者:
Ren, Zhi-Hong
;
Ke, Zun-Ping
;
Luo, Man
;
Shi, Yan
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/05
myocardial ischemia/reperfusion
icariin
heat shock protein 20
apoptosis
Identification of HSP70 gene in Corythucha ciliata and its expression profiles under laboratory and field thermal conditions
期刊论文
CELL STRESS & CHAPERONES, 2018, 卷号: 23, 期号: 2
作者:
Ju, Rui-Ting
;
Luo, Qing-Quan
;
Gao, Lei
;
Yang, Ji
;
Li, Bo
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/05
Heat shock protein 70
Heat stress
Laboratory population
Field population
Sycamore lace bug
Gas-filled ultrasound microbubbles enhance the immunoactivity of the HSP70-MAGEA1 fusion protein against MAGEA1-expressing tumours
期刊论文
MOLECULAR MEDICINE REPORTS, 2018, 卷号: 18, 页码: 315-321
作者:
Gao, Xing
;
Nan, Yang
;
Yuan, Yuan
;
Gong, Xue
;
Sun, Yuanyuan
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/11/19
gas-filled ultrasound microbubbles
tumour vaccine
heat shock protein 70-melanoma-associated antigen A1 fusion protein
Inhibition of HSP90 protects cultured neurons from oxygen-glucose deprivation induced necroptosis by decreasing RIP3 expression
期刊论文
JOURNAL OF CELLULAR PHYSIOLOGY, 2018, 卷号: 233, 期号: 6, 页码: 4864-4884
作者:
Wang, Zhen
;
Guo, Li-min
;
Wang, Yong
;
Zhou, Hong-kang
;
Wang, Shu-chao
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2019/12/03
cultured neurons
heat shock protein 90
necroptosis
oxygen and glucose deprivation
receptor interacting protein 3
Broad targeting of triptolide to resistance and sensitization for cancer therapy
期刊论文
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, 卷号: 104, 页码: 771-780
作者:
Hou, Zhen-yan
;
Tong, Xiao-pei
;
Peng, Yong-bo
;
Zhang, Bi-Kui*
;
Yan, Miao*
收藏
  |  
浏览/下载:50/0
  |  
提交时间:2019/12/03
ABC
ATP-binding cassette
AKT
V-Akt murine thymoma viral oncogene homolog
ALDH1
aldehyde dehydrogenase 1
AR
androgen receptor
Bad
Bcl-2-associated death promoter
Bak
Bcl-2 homologous antagonist killer
Bax
Bcl-2-associated X protein
Bcl-2
B-cell lymphoma
Bcl-xL
Bcl-extra large
Bcl-xs
Bcl-extra short
BCRP
breast cancer resistance protein
Bid
BH3 interacting domain death agonist
Bik
Bcl-2-interacting killer
BNIP3
Bcl2/adenovirus E1B 19 kDa protein-interacting protein 3
CAF
cancer-associated fibroblast
CAIX
carbonic anhydrase IX
cFLIP
cellular FLICE (FADD-like IL-1β-converting enzyme)-inhibitory protein
ChIP
chromatin immunoprecipitation
CI
Combination Index
cIAP1/2
cellular IAP1/2
CML
chronic myelogenous leukemia
CSC
cancer stem cell
DISC
death-inducing signaling complex
DR
death receptor
DRI
Dose Reduction Index
ECM
extracellular matrix
EMT
epithelial-mesenchymal transition
EpCAM
epithelial cell adhesion molecule
GLUT
glucose transporter
GSK3β
glycogen synthase kinase-3β
HIF-1
hypoxia inducible factor-1
HSF1
heat shock factor 1
HSP
heat shock protein
IAP
inhibitor of apoptosis protein
JNK
c-JUN N-terminal kinase
MAPK
mitogen-activated protein kinase
Mcl-1
myeloid leukemia cell differentiation protein
MDM2
murine double minute 2
MDR
multidrug resistance
MKP
MAPK phosphatase
MRP1
multidrug resistance protein 1
NF-κB
nuclear factor-kappaB
pAkt
phosphor-Akt
PARP
poly ADP-ribose polymerase
P-gp
P-glycoprotein
PI3K-PTEN
phosphatidylinositol 3-kinase-phosphatase and tensin homolog
PKC
phosphorylated at Ser9 by protein kinase C
pp2A
protein phosphatase 2A
REST
repressor element-1 silencing transcription factor
SAR
structure-activity relationship
TAM
tumor-associated macrophage
TFIIH
transcription factor IIH
TKI
tyrosine kinase inhibitor
TM
tumor-microenvironment
TRAIL/Apo-2L
TNF-related apoptosis-inducing ligand
tRXRα
the N-terminal truncated form of the nuclear retinoid X receptor-α
TWHF
Tripterygium wilfordii Hook F
VEGF
vascular endothelial growth factor
XIAP
X-linked IAP
XPB
xerodermapigmentosum group B protein
Triptolide
Antineoplastic
Resistance
Sensitization
Mechanism
Heat Shock Protein 40 (HSP40) in Pacific White Shrimp (Litopenaeus vannamei): Molecular Cloning, Tissue Distribution and Ontogeny, Response to Temperature, Acidity/Alkalinity and Salinity Stresses, and Potential Role in Ovarian Development
期刊论文
FRONTIERS IN PHYSIOLOGY, 2018, 卷号: 9, 页码: 1784
作者:
Ren, Chunhua
;
Chen, Ting
;
Lin, Tiehao
;
Li, Hongmei
;
Lu, Ting
收藏
  |  
浏览/下载:102/0
  |  
提交时间:2019/08/28
heat shock protein
HSP40
tissue distribution and ontogeny
environmental stress
ovarian development
crustacean
3'-epi-12β-hydroxyfroside, a new cardenolide, induces cytoprotective autophagy via blocking the Hsp90/Akt/mTOR axis in lung cancer cells
期刊论文
Theranostics, 2018, 卷号: Vol.8 No.7, 页码: 2044-2060
作者:
Sun, Y.
;
Huang, Y.-H.
;
Huang, F.-Y.
;
Mei, W.-L.
;
Liu, Q.
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/02/25
3'-epi-12β-hydroxyfroside
apoptosis
autophagy
cardiac
glycosides
heat
shock
protein
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