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Discovery of FS36 as a Novel Human Hsp90 Inhibitor 期刊论文
PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS, 2018, 卷号: 45, 期号: 7, 页码: 736-744
作者:  Li Gen;  Lu Kai-Kai;  Li Jian;  Yin Xiu-Shan;  Zhao Dong
收藏  |  浏览/下载:22/0  |  提交时间:2019/01/08
Design, synthesis and pharmacological evaluation of ALK and Hsp90 dual inhibitors bearing resorcinol and 2,4-diaminopyrimidine motifs 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 152, 页码: 76-86
作者:  Geng, Kaijun;  Liu, Hongchun;  Song, Zilan;  Zhang, Chi;  Zhang, Minmin
收藏  |  浏览/下载:181/0  |  提交时间:2019/01/08
HSPA12B overexpression induces cisplatin resistance in non-small-cell lung cancer by regulating the PI3K/Akt/NF-kappa B signaling pathway 期刊论文
ONCOLOGY LETTERS, 2018, 卷号: 15, 期号: 3
作者:  Chen, Wei;  Liu, Xiaoqun;  Yuan, Sujuan;  Qiao, Tiankui
收藏  |  浏览/下载:7/0  |  提交时间:2019/12/05
Icariin protects against ischemia-reperfusion injury in H9C2 cells by upregulating heat shock protein 20 期刊论文
MOLECULAR MEDICINE REPORTS, 2018, 卷号: 17, 期号: 2
作者:  Ren, Zhi-Hong;  Ke, Zun-Ping;  Luo, Man;  Shi, Yan
收藏  |  浏览/下载:5/0  |  提交时间:2019/12/05
Identification of HSP70 gene in Corythucha ciliata and its expression profiles under laboratory and field thermal conditions 期刊论文
CELL STRESS & CHAPERONES, 2018, 卷号: 23, 期号: 2
作者:  Ju, Rui-Ting;  Luo, Qing-Quan;  Gao, Lei;  Yang, Ji;  Li, Bo
收藏  |  浏览/下载:5/0  |  提交时间:2019/12/05
Gas-filled ultrasound microbubbles enhance the immunoactivity of the HSP70-MAGEA1 fusion protein against MAGEA1-expressing tumours 期刊论文
MOLECULAR MEDICINE REPORTS, 2018, 卷号: 18, 页码: 315-321
作者:  Gao, Xing;  Nan, Yang;  Yuan, Yuan;  Gong, Xue;  Sun, Yuanyuan
收藏  |  浏览/下载:8/0  |  提交时间:2019/11/19
Inhibition of HSP90 protects cultured neurons from oxygen-glucose deprivation induced necroptosis by decreasing RIP3 expression 期刊论文
JOURNAL OF CELLULAR PHYSIOLOGY, 2018, 卷号: 233, 期号: 6, 页码: 4864-4884
作者:  Wang, Zhen;  Guo, Li-min;  Wang, Yong;  Zhou, Hong-kang;  Wang, Shu-chao
收藏  |  浏览/下载:9/0  |  提交时间:2019/12/03
Broad targeting of triptolide to resistance and sensitization for cancer therapy 期刊论文
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, 卷号: 104, 页码: 771-780
作者:  Hou, Zhen-yan;  Tong, Xiao-pei;  Peng, Yong-bo;  Zhang, Bi-Kui*;  Yan, Miao*
收藏  |  浏览/下载:50/0  |  提交时间:2019/12/03
ABC  ATP-binding cassette  AKT  V-Akt murine thymoma viral oncogene homolog  ALDH1  aldehyde dehydrogenase 1  AR  androgen receptor  Bad  Bcl-2-associated death promoter  Bak  Bcl-2 homologous antagonist killer  Bax  Bcl-2-associated X protein  Bcl-2  B-cell lymphoma  Bcl-xL  Bcl-extra large  Bcl-xs  Bcl-extra short  BCRP  breast cancer resistance protein  Bid  BH3 interacting domain death agonist  Bik  Bcl-2-interacting killer  BNIP3  Bcl2/adenovirus E1B 19 kDa protein-interacting protein 3  CAF  cancer-associated fibroblast  CAIX  carbonic anhydrase IX  cFLIP  cellular FLICE (FADD-like IL-1β-converting enzyme)-inhibitory protein  ChIP  chromatin immunoprecipitation  CI  Combination Index  cIAP1/2  cellular IAP1/2  CML  chronic myelogenous leukemia  CSC  cancer stem cell  DISC  death-inducing signaling complex  DR  death receptor  DRI  Dose Reduction Index  ECM  extracellular matrix  EMT  epithelial-mesenchymal transition  EpCAM  epithelial cell adhesion molecule  GLUT  glucose transporter  GSK3β  glycogen synthase kinase-3β  HIF-1  hypoxia inducible factor-1  HSF1  heat shock factor 1  HSP  heat shock protein  IAP  inhibitor of apoptosis protein  JNK  c-JUN N-terminal kinase  MAPK  mitogen-activated protein kinase  Mcl-1  myeloid leukemia cell differentiation protein  MDM2  murine double minute 2  MDR  multidrug resistance  MKP  MAPK phosphatase  MRP1  multidrug resistance protein 1  NF-κB  nuclear factor-kappaB  pAkt  phosphor-Akt  PARP  poly ADP-ribose polymerase  P-gp  P-glycoprotein  PI3K-PTEN  phosphatidylinositol 3-kinase-phosphatase and tensin homolog  PKC  phosphorylated at Ser9 by protein kinase C  pp2A  protein phosphatase 2A  REST  repressor element-1 silencing transcription factor  SAR  structure-activity relationship  TAM  tumor-associated macrophage  TFIIH  transcription factor IIH  TKI  tyrosine kinase inhibitor  TM  tumor-microenvironment  TRAIL/Apo-2L  TNF-related apoptosis-inducing ligand  tRXRα  the N-terminal truncated form of the nuclear retinoid X receptor-α  TWHF  Tripterygium wilfordii Hook F  VEGF  vascular endothelial growth factor  XIAP  X-linked IAP  XPB  xerodermapigmentosum group B protein  Triptolide  Antineoplastic  Resistance  Sensitization  Mechanism  
Heat Shock Protein 40 (HSP40) in Pacific White Shrimp (Litopenaeus vannamei): Molecular Cloning, Tissue Distribution and Ontogeny, Response to Temperature, Acidity/Alkalinity and Salinity Stresses, and Potential Role in Ovarian Development 期刊论文
FRONTIERS IN PHYSIOLOGY, 2018, 卷号: 9, 页码: 1784
作者:  Ren, Chunhua;  Chen, Ting;  Lin, Tiehao;  Li, Hongmei;  Lu, Ting
收藏  |  浏览/下载:102/0  |  提交时间:2019/08/28
3'-epi-12β-hydroxyfroside, a new cardenolide, induces cytoprotective autophagy via blocking the Hsp90/Akt/mTOR axis in lung cancer cells 期刊论文
Theranostics, 2018, 卷号: Vol.8 No.7, 页码: 2044-2060
作者:  Sun, Y.;  Huang, Y.-H.;  Huang, F.-Y.;  Mei, W.-L.;  Liu, Q.
收藏  |  浏览/下载:5/0  |  提交时间:2019/02/25


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