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浏览/检索结果: 共6条，第1-6条 帮助 限定条件 发表日期：2017     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Discovery of potent 2,4-difluoro-linker poly(ADP-ribose) polymerase 1 inhibitors with enhanced water solubility and in vivo anticancer efficacy 期刊论文 ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 11, 页码: 1521-1532 作者:  Chen, Wen-hua;  Song, Shan-shan;  Qi, Ming-hui;  Huan, Xia-juan;  Wang, Ying-qing 收藏  |  浏览/下载：26/0  |  提交时间：2019/01/08 PARP-1 inhibitor  olaparib  breast cancer  BRCA-deficient tumors   NF90 regulates PARP1 mRNA stability in hepatocellular carcinoma 期刊论文 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2017, 卷号: 488, 期号: 1 作者:  Song, Dan;  Huang, Huixing;  Wang, Juanjuan;  Zhao, Yahui;  Hu, Xiaoding 收藏  |  浏览/下载：9/0  |  提交时间：2019/12/05 NF90  PARP1  mRNA stability  Hepatocellular carcinoma  PARP inhibitor   Synthesis of the novel PARP-1 inhibitor AG-690/11026014 and its protective effects on angiotensin II-induced mouse cardiac remodeling 期刊论文 ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 5, 页码: 638-650 作者:  Feng, Guo-shuai;  Zhu, Cui-ge;  Li, Zhuo-ming;  Wang, Pan-xia;  Huang, Yi 收藏  |  浏览/下载：9/0  |  提交时间：2019/12/12 cardiac remodeling  PARP-1 inhibitor  6014  PARylation  NAD  SIRT-1   Discovery of 2-substituted 1H-benzo[d]immidazole-4-carboxamide derivatives as novel poly(ADP-ribose)polymerase-1 inhibitors with in vivo anti-tumor activity 期刊论文 2017, 卷号: 132, 页码: 26-41 作者:  Zhou Jie;  Ji Ming;  Zhu Zhixiang;  Cao Ran;  Chen Xiaoguang 收藏  |  浏览/下载：4/0  |  提交时间：2020/01/04 PARP-1 inhibitor  PARP-2 inhibitor  Benzo[d]immidazole-4-carboxamide  Anti-tumor agents   Discovery of novel quinazoline-2,4(1H,3H)-dione derivatives as potent PARP-2 selective inhibitors 期刊论文 2017, 卷号: 25, 期号: 15, 页码: 4045-4054 作者:  Zhao, Hailong;  Ji, Ming;  Cui, Guonan;  Zhou, Jie;  Lai, Fangfang 收藏  |  浏览/下载：4/0  |  提交时间：2020/01/04 Quinazoline-2  4(1H  3H)-dione  PARP-2 selective inhibitor  Anti-tumor agents   discoveryofpotent24difluorolinkerpolyadpribosepolymerase1inhibitorswithenhancedwatersolubilityandinvivoanticancerefficacy 期刊论文 actapharmacologicasinica, 2017, 卷号: 38, 期号: 11, 页码: 1521 作者:  Chen Wenhua;  Song Shanshan;  Ql Minghui;  Huan Xiajuan;  Wang Yingqing 收藏  |  浏览/下载：5/0  |  提交时间：2020/07/01 PARP INHIBITORS  MEDICINAL CHEMISTRY  DRUG DISCOVERY  CANCER  THERAPY  DESIGN  FLUORINE  SUCCESS  PREDICT  METRICS  PARP-1 inhibitor  olaparib  breast cancer  BRCA-deficient tumors