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科研机构
复旦大学上海医学院 [15]
上海药物研究所 [13]
山东大学 [11]
中国医学科学院 北京... [8]
中南大学 [6]
武汉大学 [6]
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内容类型
期刊论文 [108]
发表日期
2017 [108]
学科主题
biochemist... [1]
pharmacolo... [1]
生物科学::普通生物... [1]
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浏览/检索结果:
共108条,第1-10条
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发表日期:2017
内容类型:期刊论文
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Pharmacologic characterization of SHR8443, a novel dual inhibitor of phosphatidylinositol 3-kinase and mammalian target of rapamycin
期刊论文
ONCOTARGET, 2017, 卷号: 8, 期号: 64, 页码: 107977-107990
作者:
Xie, Chengying
;
Chen, Xiangling
;
Zheng, Mingyue
;
Liu, Xiaohong
;
Wang, Hongbin
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2019/01/08
BEZ235
drug resistance
mTOR
PI3K
SHR8443
Genomic insights into the pathogenicity and environmental adaptability of Enterococcus hirae R17 isolated from pork offered for retail sale
期刊论文
MICROBIOLOGYOPEN, 2017, 卷号: 6, 期号: 6, 页码: 15
作者:
Peng, Zixin
;
Li, Menghan
;
Wang, Wei
;
Liu, Hongtao
;
Fanning, Seamus
收藏
  |  
浏览/下载:47/0
  |  
提交时间:2019/05/30
drug-resistance gene
Enterococcus hirae
genomic island
genomic plasticity
mobile genetic element
virulence gene
Hypoxia induces universal but differential drug resistance and impairs anticancer mechanisms of 5-fluorouracil in hepatoma cells
期刊论文
ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 12, 页码: 1642-1654
作者:
Li, Jing-qiu
;
Wu, Xian
;
Gan, Lu
;
Yang, Xiang-liang
;
Miao, Ze-hong
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2019/01/08
hepatocellular carcinoma
hypoxia
5-fluorouracil
sorafenib
drug resistance
Reprogramming Tumor-Associated Macrophages To Reverse EGFR(T790M) Resistance by Dual-Targeting Codelivery of Gefitinib/Vorinostat
期刊论文
NANO LETTERS, 2017, 卷号: 17, 期号: 12, 页码: 7684-7690
作者:
Peng, Huige
;
Chen, Binfan
;
Huang, Wei
;
Tang, Yubo
;
Jiang, Yifan
收藏
  |  
浏览/下载:70/0
  |  
提交时间:2019/01/08
Tumor-associated macrophages
gefitinib
vorinostat
EGFR(T790M)
nonsmall cell lung cancer
drug resistance
Overcoming resistance to cisplatin by inhibition of glutathione s-transferases (gsts) with ethacraplatin micelles in vitro and in vivo
期刊论文
Biomaterials, 2017, 卷号: 144, 页码: 119-129
作者:
Li, Shuyi
;
Li, Chan
;
Jin, Shubin
;
Liu, Juan
;
Xue, Xiangdong
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2019/04/23
Cisplatin resistance
Glutathione s-transferases (gsts)
Ethacraplatin
Drug delivery
Click chemistry-based synthesis and anticancer activity evaluation of novel C-14 1,2,3-triazole dehydroabietic acid hybrids
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 138, 页码: 1042-1052
作者:
Hou, Wei
;
Luo, Zhi
;
Zhang, Guanjun
;
Cao, Danhui
;
Li, Di
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2019/01/08
Terpenoids
Dehydroabietic acid
Cancer
1,2,3-triazole
Synthesis
Click chemistry
Drug resistance
LLDT-288, a novel triptolide analogue exhibits potent antitumor activity in vitro and in vivo
期刊论文
BIOMEDICINE & PHARMACOTHERAPY, 2017, 卷号: 93, 页码: 1004-1009
作者:
Xu, Hongtao
;
Fan, Xiaoting
;
Zhang, Guanjun
;
Liu, Xiaoyu
;
Li, Zhihong
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2019/01/08
Triptolide
Natural products
Drug-resistance
CYP
Site-specific drug-releasing polypeptide nanocarriers with enhanced therapeutic efficacy against drug-resistant tumors
期刊论文
JOURNAL OF CONTROLLED RELEASE, 2017, 卷号: 259, 页码: E71-E71
作者:
Yang, Jun
;
Dong, Yaqiong
;
Zhang, Xin
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2017/11/27
Site-specific Releasing
Polypeptide Nanocarrier
Sequential Ph-response
Drug Resistance
Drug resistance mutation profiles of the drug-na < ve and first-line regimen-treated hiv-1-infected population of suzhou, china
期刊论文
Virologica sinica, 2017, 卷号: 32, 期号: 4, 页码: 271-279
作者:
Li, Tingting
;
Qian, Feng
;
Yuan, Ting
;
Xu, Weilu
;
Zhu, Li
收藏
  |  
浏览/下载:60/0
  |  
提交时间:2019/05/08
Hiv-1
Drug resistance mutation
First-line regimen
China
Near infrared light triggered nitric oxide releasing platform based on upconversion nanoparticles for synergistic therapy of cancer stem-like cells
期刊论文
Science bulletin, 2017, 卷号: 62, 期号: 14, 页码: 985-996
作者:
Zhang, Xiao
;
Guo, Zhao
;
Liu, Jing
;
Tian, Gan
;
Chen, Kui
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2019/04/23
Upconversion nanoparticles
Nitric oxide
Cancer stem-like cells
Synergistic effect of no and chemotherapy
Drug resistance reversal
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