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CORC

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Discovery of 4-chloro-3-(5-(pyridin-3-yl)-1,2,4-oxadiazole-3-yl) benzamides as novel RET kinase inhibitors 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2016, 卷号: 26, 期号: 23, 页码: 5679-5684
作者:  Han, Mei;  Li, Shan;  Ai, Jing;  Sheng, Rong;  Hu, Yongzhou
收藏  |  浏览/下载：20/0  |  提交时间：2019/01/08
Revealing the molecular mechanism of different residence times of ERK2 inhibitors via binding free energy calculation and unbinding pathway analysis 期刊论文
CHEMOMETRICS AND INTELLIGENT LABORATORY SYSTEMS, 2016, 卷号: 158, 页码: 91-101
作者:  Niu, YZ;  Pan, DB;  Yang, YJ;  Liu, HX;  Yao, XJ
收藏  |  浏览/下载：1/0  |  提交时间：2017/05/08
Molecular regulation of apoptotic machinery and lipid metabolism by mTORC1/mTORC2 dual inhibitors in preclinical models of HER2+/PIK3CAmut breast cancer 期刊论文
ONCOTARGET, 2016, 卷号: 7, 期号: 41, 页码: 67071-67086
作者:  Qian, Jianchang;  Chen, Yaqing;  Meng, Tao;  Ma, Lanping;  Meng, Lanfang
收藏  |  浏览/下载：34/0  |  提交时间：2019/01/08
Discovery and characterization of a novel potent type II native and mutant BCR-ABL inhibitor (CHMFL-074) for Chronic Myeloid Leukemia (CML) 期刊论文
ONCOTARGET, 2016, 卷号: 7, 期号: 29, 页码: 45562-45574
作者:  Liu, Feiyang;  Wang, Beilei;  Wang, Qiang;  Qi, Ziping;  Chen, Cheng
收藏  |  浏览/下载：39/0  |  提交时间：2017/11/21
Discovery of 6-(difluoro(6-(4-fluorophenyl)-[1,2,4]triazolo[4,3-b] [1,2,4]triazin-3-yl)methyl)quinoline as a highly potent and selective c-Met inhibitor 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2016, 卷号: 116, 页码: 239-251
作者:  Zhan, Zhengsheng;  Peng, Xia;  Liu, Qiufeng;  Chen, Fang;  Ji, Yinchun
收藏  |  浏览/下载：50/0  |  提交时间：2019/01/08
Simm530, a novel and highly selective c-Met inhibitor, blocks c-Met-stimulated signaling and neoplastic activities 期刊论文
ONCOTARGET, 2016, 卷号: 7, 期号: 25, 页码: 38091-38104
作者:  Wang, Ying;  Zhan, Zhengsheng;  Jiang, Xifei;  Peng, Xia;  Shen, Yanyan
收藏  |  浏览/下载：51/0  |  提交时间：2019/01/08
Discovery and structure activity relationship study of novel indazole amide inhibitors for extracellular signal-regulated kinase1/2 (ERK1/2) 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2016, 卷号: 26, 期号: 11, 页码: 2600-2604
作者:  Li, Lei;  Liu, Feifei;  Jin, Nan;  Tang, Shuai;  Chen, Zhuxi
收藏  |  浏览/下载：15/0  |  提交时间：2019/01/08
Design, synthesis and biological evaluation of biphenylurea derivatives as VEGFR-2 kinase inhibitors (II) 期刊论文
CHINESE CHEMICAL LETTERS, 2016, 卷号: 27, 期号: 2, 页码: 200-204
作者:  Gao, Guo-Rui;  Li, Meng-Yuan;  Lv, Yong-Cong;  Cao, Su-Fen;  Tong, Lin-Jiang
收藏  |  浏览/下载：11/0  |  提交时间：2019/01/08
Synthesis and biological evaluation of Oblongifolin C derivatives as c-Met inhibitors 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2016, 卷号: 24, 期号: 18
作者:  Wang, Liping;  Wu, Rong;  Fu, Wenwei;  Lao, Yuanzhi;  Zheng, Changwu
收藏  |  浏览/下载：5/0  |  提交时间：2019/12/05
Cardiotoxicity associated with targeted cancer therapies (Review) 期刊论文
MOLECULAR AND CLINICAL ONCOLOGY, 2016, 卷号: 4, 期号: 5
作者:  Chen, Zi;  Ai, Di
收藏  |  浏览/下载：3/0  |  提交时间：2019/12/05

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