Apoptosis  Cell growth  Gastric cancer  Insulin-like growth factor-1 receptor  Metastasis  RNA interference  

Akt  epilepsy seizures  ERK1/2  insulin-like growth factor-1  insulin-like growth factor-1 receptor  

胰岛素样生长因子1受体  骨肉瘤  预后  生存  Insulin-like growth factor receptor  Osteosarcoma  Prognosis  Survival  

OS  osteosarcoma  miRNAs  microRNAs  CSCs  cancer stem cells  RNA pol  RNA polymerase  DGCR8  DiGeorge syndrome critical gene 8  RISC  RNA-induced silencing complex  Exp 5  exportin 5  Ago  argonaute  MREs  miRNA recognition elements  APE1  apurinic/apyrimidinic endonuclease 1  MDM  murine double minute  TP53  tumor suppressor p53  mTOR  mammalian target of rapamycin  Eag1  ether à go-go 1  PI3K  phosphatidylinositol-3-kinase  PTEN  phosphatase and tensin homolog deleted on chromosome ten  Hsp90B1  heat shock protein 90B1  BMP2  bone morphogenetic protein 2  IGF1R  insulin-like growth factor 1 receptor  FAK  phospho-Akt and focal adhesion kinase  LPAATβ  lysophosphatidic acid acyltransferase β  HMGB1  high-mobility group box 1  FASN  fatty acid synthase  LZTS1  leucine zipper putative tumor suppressor 1  MMP  matrix metalloproteinase  LNA  locked nucleic acid  DATS  diallyl trisulfide  miRNAs  OS  TP53  Notch  Chemoresistance  

apo  apolipoprotein  HDL  high-density lipoprotein  HNF-1α,4α  hepatocyte nuclear factor-1α,4α  LRH-1  liver receptor homolog-1  Foxa2  forkhead box A2  PAF  platelet activating factor  LXR  liver X receptor  RXR  retinoid X receptor  FXR  farnesoid X receptor  SHP  small heterodimer partner  S1P  Sphingosine-1-Phosphate  CVD  cardiovascular disease  HDL-C  HDL cholesterol  RCT  reverse cholesterol transport  MHC  major histocompatibility complex class III  TNF  tumor necrosis factor  HRP  haptoglobin-related protein  PON-I  paraoxonase-1  SNP  single nucleotide polymorphism  T1,2D  type 1,2 diabetes  RA  rheumatoid arthritis  ABCA1  ATP-binding cassette transporter A1  PPAR-γ  peroxisome proliferator-activated receptor γ  IL  interleukin  ABCG  ATP-binding cassette sub-family G  CETP  cholesteryl ester transfer protein  SR-B1  scavenger receptor class B member 1  MODY3  maturity-onset diabetes of the young type 3  MUP  major urinary protein  RBP  retinol binding protein  RAR  retinoic acid receptor  TR  thyroid hormone receptor  PI3K  phosphatidylinositol 3-kinase  DHC  dihydrocapsaicin  HRE  hormone response element  IGF-1  insulin-like growth factors  PAF-R  platelet activating factor receptor  TGF-α,β  transforming growth factor-α,β  EGF  epidermal growth factor  HGF  hepatic growth factor  VLDL  very low-density lipoprotein  LDL  low-density lipoprotein  ldlr  LDL receptor  ldlr−/−  LDL-receptor deficient  LCAT  lecithin-cholesterol acyltransferase  CE  cholesteryl ester  TC  total cholesterol  LDL-C  LDL cholesterol  VLDL-C  VLDL cholesterol  CHD  coronary heart disease  Mets  metabolic syndrome  S1PR  S1P receptor  NF-κB  nuclear factor-κB  NO  nitrogen oxide  eNOS  endothelial nitric oxide synthase  apoM-TgN mice  mice overexpressing human apoM by approximately two-fold  apoM-TgH mice  mice overexpressing human apoM by approximately ten-fold  apoM−/− mice  apoM-null mice  apoE−/−  apoE-null mice  Apolipoprotein M  Regulation  Function