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浏览/检索结果: 共8条，第1-8条 帮助 限定条件 发表日期：2014     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Topoisomerase II inhibitors from the roots of Stellera chamaejasme L. 期刊论文 BIOORGANIC & MEDICINAL CHEMISTRY, 2014, 卷号: 22, 期号: 15, 页码: 4198-4203 作者:  Liu, Li-Ping;  Han, Kun;  Chen, Wei;  Zhang, Ying-Ying;  Tong, Lin-Jiang 收藏  |  浏览/下载：15/0  |  提交时间：2019/01/08 Stellera chamaejasme L.  Cytotoxic activity  Topoisomerase II  Apoptosis   A rational design strategy of the novel topoisomerase II inhibitors for the synthesis of the 4-O-(2-pyrazinecarboxylic)-4 '-demethylepipodophyllotoxin with antitumor activity by diminishing the relaxation reaction of topoisomerase II-DNA decatenation 期刊论文 BIOORGANIC & MEDICINAL CHEMISTRY, 2014, 卷号: 22, 期号: 11 作者:  Zhao, Wei;  Chen, Lu;  Li, Hong-Mei;  Wang, Duan-Ji;  Li, Dong-Sheng 收藏  |  浏览/下载：2/0  |  提交时间：2019/12/05 Rational drug design strategy  4 '-Demethylepipodophyllotoxin derivates  Antitumor activity  Topoisomerase II  Cell cycle arrest  Apoptosis   SAR analysis and biological studies of synthesized podophyllum derivates obtained by N linkage modification at C-4 position 期刊论文 BIOORGANIC & MEDICINAL CHEMISTRY, 2014, 卷号: 22, 期号: 21 作者:  Wang, Huai;  Tang, Lijun;  Tang, Yajie;  Yuan, Zhanpeng 收藏  |  浏览/下载：3/0  |  提交时间：2019/12/05 Podophyllum derivates  N linkage  SAR  Microtubule  Topoisomerase II   Design and synthesis of 2-phenylnaphthalenoids as inhibitors of DNA topoisomeraseIIα and antitumor agents 期刊论文 European Journal of Medicinal Chemistry, 2014, 卷号: 86, 页码: 782-796 作者:  Chen W.;  Shen Y.;  Li Z.;  Zhang M.;  Lu C. 收藏  |  浏览/下载：7/0  |  提交时间：2019/12/17 2-Phenylnaphthalenoids  Antitumor  Quantitative structureeactivity  relationships (QSAR  Topoisomerase II (TopoII)   Synthesis of Aryl-Substituted Naphthalenoids as Potent Topoisomerase Inhibitors 期刊论文 MEDICINAL CHEMISTRY, 2014, 卷号: 10, 期号: 5, 页码: 533-539 作者:  Shen, Yan;  Chen, Wang;  Li, Zhenyu;  Shen, Yuemao 收藏  |  浏览/下载：2/0  |  提交时间：2019/12/17 Topoisomerase I  topoisomerase II alpha  aryl-substituted  naphthalenoids  antitumor activity   CS1 is a novel topoisomerase II alpha inhibitor with favorable drug resistance profiles 期刊论文 Biochemical and Biophysical Research Communications, 2014, 卷号: 453, 期号: 3, 页码: 302-308 作者:  Shen, Yan;  Chen, Wang;  Zhao, Baobing;  Hao, Huilin;  Li, Zhenyu 收藏  |  浏览/下载：3/0  |  提交时间：2019/12/17 2-Phenylnaphthalene  Topoisomerase II inhibitor  Multidrug resistance  DNA breaks   Synthesis and Biological Activity of Anthrapyrazoles Derivatives as Potential Antitumor Agents 期刊论文 MEDICINAL CHEMISTRY, 2014, 卷号: 10, 期号: 8, 页码: 772-777 作者:  Wang, Jianhong[1];  Zhao, Huijun[2];  Luo, Zhaoyang[3];  Wang, Zhaoyi[4];  Zhang, Yahong[5] 收藏  |  浏览/下载：2/0  |  提交时间：2019/12/23 Anthrapyrazoles derivatives  cytotoxicity  topoisomerase II inhibition  polyamine   g226anewepipolythiodioxopiperazinederivativetriggersdnadamageandapoptosisinhumancancercellsinvitroviarosgeneration 期刊论文 actapharmacologicasinica, 2014, 卷号: 35, 期号: 12, 页码: 1546 作者:  He Pengxing;  Zhang Jie;  Che Yongsheng;  He Qiaojun;  Chen Yi 收藏  |  浏览/下载：16/0  |  提交时间：2020/07/01 DOUBLE-STRAND BREAKS  TOPOISOMERASE-II  OXIDATIVE STRESS  INHIBITION  SURVIVAL  ARREST  ROLES  G226  epipolythiodioxopiperazine  11 '-deoxyverticillin A  anti-cancer agent  Topo II  DNA damage  apoptosis  ROS  antioxidant