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浏览/检索结果: 共11条，第1-10条 帮助 限定条件 专题：复旦大学上海医学院    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Targeting EGFR/HER2 heterodimerization with a novel anti-HER2 domain II/III antibody 期刊论文 MOLECULAR IMMUNOLOGY, 2017, 卷号: 87 作者:  Yu, Xiaojie;  Wang, Lingfei;  Shen, Yafeng;  Wang, Chao;  Zhang, Yajun 收藏  |  浏览/下载：4/0  |  提交时间：2019/12/05 Breast cancer  HER2  Transmembrane signal transduction  Structural analysis   Combating acquired resistance to trastuzumab by an anti-ErbB2 fully human antibody 期刊论文 ONCOTARGET, 2017, 卷号: 8, 期号: 26 作者:  Wang, Chao;  Wang, Lingfei;  Yu, Xiaojie;  Zhang, Yajun;  Meng, Yanchun 收藏  |  浏览/下载：7/0  |  提交时间：2019/12/05 ErbB2  gastric cancer  acquired resistance to trastuzumab  domain I- specific antibody  programmed cell death   The anti-ErbB2 antibody H2-18 and the pan-PI3K inhibitor GDC-0941 effectively inhibit trastuzumab-resistant ErbB2-overexpressing breast cancer 期刊论文 ONCOTARGET, 2017, 卷号: 8, 期号: 32 作者:  Wang, Lingfei;  Yu, Xiaojie;  Wang, Chao;  Pan, Shujun;  Liang, Beibei 收藏  |  浏览/下载：13/0  |  提交时间：2019/12/05 trastuzumab resistance  GDC-0941  anti-ErbB2 antibody  programmed cell death  breast cancer   Combined SRC inhibitor saracatinib and anti-ErbB2 antibody H2-18 produces a synergistic antitumor effect on trastuzumab-resistant breast cancer 期刊论文 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2016, 卷号: 479, 期号: 3 作者:  Wang, Lingfei;  Yu, Xiaojie;  Dong, Jian;  Meng, Yanchun;  Yang, Yang 收藏  |  浏览/下载：4/0  |  提交时间：2019/12/05 Breast cancer  Saracatinib  Anti-ErbB2 antibody  Cell death  Trastuzumab resistance   An anti-ErbB2 fully human antibody circumvents trastuzumab resistance 期刊论文 Oncotarget, 2016, 卷号: 7, 期号: 41 作者:  Lu, Qiong/56565883900[0];  Wang, Lingfei/57190396688[1];  Zhang, Yajun/56566403800[2];  Yu, Xiaojie/37085684600[3];  Wang, Chao/56566115000[4] 收藏  |  浏览/下载：4/0  |  提交时间：2019/12/05 Breast cancer  Domain I- specific antibody  ErbB2  Programmed cell death  Trastuzumab resistance   In-Depth Characterization of a Pro-Antibody-Drug Conjugate by LC-MS 期刊论文 MOLECULAR PHARMACEUTICS, 2016, 卷号: 13, 期号: 8 作者:  Liu, Boning;  Guo, Huaizu;  Zhang, Junjie;  Xue, Jingya;  Yang, Yun 收藏  |  浏览/下载：9/0  |  提交时间：2019/12/05 pro-antibody-drug conjugates  structural characterization  drug-to-antibody ratio  drug load distribution  drug-loaded peptide mapping  drug occupation site  IdeS  liquid chromatography mass spectrometry  charge heterogeneity   A bispecific anti-ErbB2 antibody potently induces ErbB2 internalization and suppresses ErbB2-overexpressing tumor growth 期刊论文 Biochemical and Biophysical Research Communications, 2016, 卷号: 477, 期号: 4 作者:  Zhang, Yajun/56566403800[0];  Wang, Lingfei/57190396688[1];  Chong, Xiaodan/57190392543[2];  Yu, Xiaojie/37085684600[3];  Meng, Yanchun/36994996100[4] 收藏  |  浏览/下载：8/0  |  提交时间：2019/12/06 Bispecific antibody  Down-regulation  ErbB2  Gastric cancer  Monoclonal antibody   Molecular architecture of the ErbB2 extracellular domain homodimer 期刊论文 Oncotarget, 2015, 卷号: 6, 期号: 3 作者:  Hu, Shi/56434897100[0];  Sun, Yuna/8845600300[1];  Meng, Yanchun/36994996100[2];  Wang, Xiaoze/55863421400[3];  Yang, Weili/55501159500[4] 收藏  |  浏览/下载：7/0  |  提交时间：2019/12/13 Crystal structure  Dimerization  ErbB2  Oncogene  Signal transduction   Optimization of anti-CD20 humanized antibody hu8E4 by site-directed mutation based on epitope analysis 期刊论文 Biochemical and Biophysical Research Communications, 2015, 卷号: 459, 期号: 4 作者:  Chen, Yalin/56075105500[0];  Chen, Lin/57192609752[1];  Lu, Qiong/56565883900[2];  Meng, Yanchun/36994996100[3];  Wang, Chao/56566115000[4] 收藏  |  浏览/下载：7/0  |  提交时间：2019/12/19 CD20 B-cell lymphoma Humanized antibody Epitope Affinity   The ErbB2-targeting antibody trastuzumab and the small-molecule SRC inhibitor saracatinib synergistically inhibit ErbB2-overexpressing gastric cancer 期刊论文 mAbs, 2014, 卷号: 6, 期号: 2 作者:  Han, Siqi/56228396400[0];  Meng, Yanchun/36994996100[1];  Tong, Qing/35300973300[2];  Li, Guangchao/56074376900[3];  Zhang, Xunmin/35363203900[4] 收藏  |  浏览/下载：11/0  |  提交时间：2019/12/19 ErbB2  Gastric cancer  Saracatinib  SRC  Trastuzumab