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Discovery of N-phenyl)-2-phenyl)acetamide as a Potent FMS-like Tyrosine Kinase 3 Internal Tandem Duplication Mutant Selective Inhibitor for Acute Myeloid Leukemia 期刊论文
Journal of Medicinal Chemistry, 2019, 卷号: Vol.62 No.2, 页码: 875-892
作者:  Tingting Lu;  Jian Ge;  Tao Ren;  Wenchao Wang;  Junjie Wang
收藏  |  浏览/下载:40/0  |  提交时间:2019/04/24
Discovery of N-phenyl)-2-phenyl)acetamide as a Potent FMS-like Tyrosine Kinase 3 Internal Tandem Duplication Mutant Selective Inhibitor for Acute Myeloid Leukemia 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: Vol.62 No.2, 页码: 875-892
作者:  Wang, Beilei;  Li, Feng;  Liu, Qingwang;  Hu, Zhenquan;  Liang, Xiaofei
收藏  |  浏览/下载:4/0  |  提交时间:2019/04/24
Discovery of (S)-2-amino-N-(5-(6-chloro-5-(3-methylphenylsulfonamido)pyridin-3-yl)-4-methylthiazol-2-yl)-3-methylbutanamide (CHMFL-PI3KD-317) as a potent and selective phosphoinositide 3-kinase delta (PI3Kδ) inhibitor 期刊论文
European Journal of Medicinal Chemistry, 2018, 卷号: Vol.156, 页码: 831-846
作者:  Zongru Jiang;  Wenliang Wang;  Fengming Zou;  Jing Liu;  Qingsong Liu
收藏  |  浏览/下载:7/0  |  提交时间:2019/04/22
Discovery of (E)-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)-3-((3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)thio)propanamide (CHMFL-ABL-121) as a highly potent ABL kinase inhibitor capable of overcoming a variety of ABL mutants including T315I for chronic myeloid leukemia 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: Vol.160, 页码: 61-81
作者:  Liu, Xiaochuan;  Wang, Beilei;  Wang, Junjie;  Zhang, Yicong;  Jiang, Zongru
收藏  |  浏览/下载:12/0  |  提交时间:2019/04/24
Discovery of 4--4-amino) cyclohexyl)amino)pyridin-4-yl)thiazol-2-yl)amino)methyl) tetrahydro-2H-pyran-4-carbonitrile as a novel highly selective and potent CDK9 kinase inhibitor 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: Vol.158, 页码: 896-916
作者:  Wang, Beilei;  Wu, Yun;  Liu, Qingwang;  Jiang, Zongru;  Wu, Jiaxin
收藏  |  浏览/下载:8/0  |  提交时间:2019/04/24


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