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科研机构
大连化学物理研究所 [12]
内容类型
期刊论文 [12]
发表日期
2019 [2]
2017 [4]
2016 [2]
2015 [3]
2013 [1]
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Cytochrome P450 3A Enzymes Are Key Contributors for Hepatic Metabolism of Bufotalin, a Natural Constitute in Chinese Medicine Chansu
期刊论文
FRONTIERS IN PHARMACOLOGY, 2019, 卷号: 10, 页码: 10
作者:
Ma, Hong-Ping
;
Dai, Zi-Ru
;
Ning, Jing
;
Sun, Gui-Bo
;
Wang, Ping
收藏
  |  
浏览/下载:67/0
  |  
提交时间:2019/06/20
bufotalin
cytochrome P450 3A (CYP3A)
hydroxylation
human liver microsomes (HLMs)
docking simulations
Cytochrome p450 3a enzymes are key contributors for hepatic metabolism of bufotalin, a natural constitute in chinese medicine chansu
期刊论文
Frontiers in pharmacology, 2019, 卷号: 10, 页码: 10
作者:
Dai, Zi-Ru
;
Ning, Jing
;
Sun, Gui-Bo
;
Wang, Ping
;
Zhang, Feng
收藏
  |  
浏览/下载:90/0
  |  
提交时间:2019/05/08
Bufotalin
Cytochrome p450 3a (cyp3a)
Hydroxylation
Human liver microsomes (hlms)
Docking simulations
Structure-activity relationships of flavonoids as natural inhibitors against E. coli beta-glucuronidase
期刊论文
FOOD AND CHEMICAL TOXICOLOGY, 2017, 卷号: 109, 页码: 975-983
作者:
Wu, Da-Chang
;
Zou, Li-Wei
;
Dou, Tong-Yi
;
Yang, Ling
;
Zhang, Tong-Yan
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2019/06/20
Flavonoids
E. Coli bE.a-glucuronidasE.
Structure-inhibition Relationships
Scutellarein
Luteolin
A novel substrate-inspired fluorescent probe to monitor native albumin in human plasma and living cells
期刊论文
ANALYTICA CHIMICA ACTA, 2017, 卷号: 989, 页码: 71-79
作者:
Ge, Guang-Bo
;
Feng, Lei
;
Jin, Qiang
;
Wang, Yi-Ru
;
Liu, Zhao-Ming
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2017/12/19
Human albumin
Fluorescent probe
Pseudo-esterase activity
Living cells
Two-photon imaging
A novel substrate-inspired fluorescent probe to monitor native albumin in human plasma and living cells
期刊论文
ANALYTICA CHIMICA ACTA, 2017, 卷号: 989, 页码: 71-79
作者:
Ge, Guang-Bo
;
Feng, Lei
;
Jin, Qiang
;
Wang, Yi-Ru
;
Liu, Zhao-Ming
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2017/12/19
Human albumin
Fluorescent probe
Pseudo-esterase activity
Living cells
Two-photon imaging
A practical strategy to design and develop an isoform-specific fluorescent probe for a target enzyme: CYP1A1 as a case study
期刊论文
CHEMICAL SCIENCE, 2017, 卷号: 8, 期号: 4, 页码: 2795-2803
作者:
Ge, Guang-Bo
;
Dai, Zi-Ru
;
Feng, Lei
;
Jin, Qiang
;
Cheng, Hailing
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2019/06/20
A highly selective near-infrared fluorescent probe for carboxylesterase 2 and its bioimaging applications in living cells and animals
期刊论文
BIOSENSORS & BIOELECTRONICS, 2016, 卷号: 83, 页码: 193-199
作者:
Jin, Qiang
;
Feng, Lei
;
Wang, Dan-Dan
;
Wu, Jing-Jing
;
Hou, Jie
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2019/06/20
Nir Fluorescent Probe
Carboxylesterase 2
Enzymatic Activity
Specific Detection
Bioimaging
A rapid-response fluorescent probe for the sensitive and selective detection of human albumin in plasma and cell culture supernatants
期刊论文
CHEMICAL COMMUNICATIONS, 2016, 卷号: 52, 期号: 36, 页码: 6064-6067
作者:
Wang, Yi-Ru
;
Feng, Lei
;
Xu, Liang
;
Li, Yan
;
Wang, Dan-Dan
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2019/06/20
A Two-Photon Ratiometric Fluorescent Probe for Imaging Carboxylesterase 2 in Living Cells and Tissues
期刊论文
ACS APPLIED MATERIALS & INTERFACES, 2015, 卷号: 7, 期号: 51, 页码: 28474-28481
作者:
Ge, Guang-Bo
;
Jin, Qiang
;
Feng, Lei
;
Wang, Dan-Dan
;
Dai, Zi-Ru
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2019/06/20
Two-photon
Ratiometric Fluorescent Probe
Carboxylesterase 2
Specific Sensing
Bioimaging
A Mechanism-Based Model for the Prediction of the Metabolic Sites of Steroids Mediated by Cytochrome P450 3A4
期刊论文
international journal of molecular sciences, 2015, 卷号: 16, 期号: 7, 页码: 14677-14694
作者:
Dai, Zi-Ru
;
Ai, Chun-Zhi
;
Ge, Guang-Bo
;
He, Yu-Qi
;
Wu, Jing-Jing
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2015/11/17
CYP3A4
steroids
metabolic site
mechanism-based prediction
activation energy
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