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科研机构
上海药物研究所 [46]
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期刊论文 [46]
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2021 [4]
2020 [7]
2019 [6]
2018 [5]
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LS-106, a novel EGFR inhibitor targeting C797S, exhibits antitumor activities both in vitro and in vivo
期刊论文
CANCER SCIENCE, 2021, 页码: 12
作者:
Liu, Yingqiang
;
Lai, Mengzhen
;
Li, Shan
;
Wang, Yanan
;
Feng, Fang
收藏
  |  
浏览/下载:62/0
  |  
提交时间:2022/01/18
C797S
epidermal growth factor receptor
fourth-generation EGFR TKI
non-small cell lung cancer
osimertinib resistance
Discovery of a novel third-generation EGFR inhibitor and identification of a potential combination strategy to overcome resistance (vol 19, 90, 2020)
期刊论文
MOLECULAR CANCER, 2021, 卷号: 20, 期号: 1, 页码: 1
作者:
Zhang, Tao
;
Qu, Rong
;
Chan, Shingpan
;
Lai, Mengzhen
;
Tong, Linjiang
收藏
  |  
浏览/下载:58/0
  |  
提交时间:2021/11/04
Correction to: Discovery of a novel third-generation EGFR inhibitor and identification of a potential combination strategy to overcome resistance
期刊论文
Molecular Cancer, 2021, 卷号: 20, 期号: 1
作者:
Zhang,Tao
;
Qu,Rong
;
Chan,Shingpan
;
Lai,Mengzhen
;
Tong,Linjiang
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2021/11/04
Design, Synthesis, and Biological Evaluation of IRAK4-Targeting PROTACs
期刊论文
ACS MEDICINAL CHEMISTRY LETTERS, 2021, 卷号: 12, 期号: 1, 页码: 82-87
作者:
Chen, Yun
;
Ning, Yi
;
Bai, Gang
;
Tong, Linjiang
;
Zhang, Tao
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2021/05/24
IRAK4
PROTAC
protein degrader
scaffolding role
diffuse large B-cell lymphoma
SETD2 Restricts Prostate Cancer Metastasis by Integrating EZH2 and AMPK Signaling Pathways
期刊论文
CANCER CELL, 2020, 卷号: 38, 期号: 3, 页码: 350-+
作者:
Yuan, Huairui
;
Han, Ying
;
Wang, Xuege
;
Li, Ni
;
Liu, Qiuli
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2020/12/24
A potential drug combination of omeprazole and patchouli alcohol significantly normalizes oxidative stress and inflammatory responses against gastric ulcer in ethanol-induced rat model
期刊论文
INTERNATIONAL IMMUNOPHARMACOLOGY, 2020, 卷号: 85, 页码: 9
作者:
Xie, Lu
;
Guo, Yi-lin
;
Chen, Yu-rou
;
Zhang, Li-ying
;
Wang, Zhi-cheng
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2020/12/24
Gastric ulcer
Omeprazole
Patchouli alcohol
Discovery of a novel third-generation EGFR inhibitor and identification of a potential combination strategy to overcome resistance
期刊论文
MOLECULAR CANCER, 2020, 卷号: 19, 期号: 1, 页码: 15
作者:
Zhang, Tao
;
Qu, Rong
;
Chan, Shingpan
;
Lai, Mengzhen
;
Tong, Linjiang
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2020/07/01
Non-small cell lung cancer (NSCLC)
EGFR T790M
Small-molecule inhibitor
Drug resistance
Ack1
Patchouli Alcohol: a Natural Sesquiterpene Against Both Inflammation and Intestinal Barrier Damage of Ulcerative Colitis
期刊论文
INFLAMMATION, 2020, 页码: 13
作者:
Wu, Zhuona
;
Zeng, Hairong
;
Zhang, Lili
;
Pu, Yiqiong
;
Li, Suyun
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2020/07/01
patchouli alcohol
ulcerative colitis
intestinal integrity
anti-inflammatory
Structural basis of ligand binding modes at the human formyl peptide receptor 2
期刊论文
NATURE COMMUNICATIONS, 2020, 卷号: 11, 期号: 1, 页码: 9
作者:
Chen, Tong
;
Xiong, Muya
;
Zong, Xin
;
Ge, Yunjun
;
Zhang, Hui
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2020/12/24
Supramolecular Prodrug Nanovectors for Active Tumor Targeting and Combination Immunotherapy of Colorectal Cancer
期刊论文
ADVANCED SCIENCE, 2020, 页码: 14
作者:
Hu, Xianli
;
Hou, Bo
;
Xu, Zhiai
;
Saeed, Madiha
;
Sun, Fang
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2020/07/01
active tumor targeting
cancer management
colorectal cancer
combination immunotherapy
photodynamic immunotherapy
prodrugs
supramolecular nanovectors
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