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科研机构
上海药物研究所 [14]
内容类型
期刊论文 [12]
会议论文 [2]
发表日期
2021 [1]
2020 [2]
2019 [2]
2017 [1]
2015 [3]
2014 [2]
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Polyoxygenated Cembranoids from Soft Coral Lobophytum Crassum and Their Anti-tumoral Activities
期刊论文
CHINESE JOURNAL OF CHEMISTRY, 2021, 卷号: 39, 期号: 3, 页码: 640-646
作者:
Yin, Fang-Zhou
;
Huan, Xia-Juan
;
Mudianta, I. Wayan
;
Miao, Ze-Hong
;
Wang, Hong
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2021/05/24
Soft coral
Lobophytum crassum
Cembranoids
Anti‐
tumoral activity
Stereochemistry
A new BET inhibitor, 171, inhibits tumor growth through cell proliferation inhibition more than apoptosis induction
期刊论文
INVESTIGATIONAL NEW DRUGS, 2020, 卷号: 38, 期号: 3, 页码: 700-713
作者:
Damaneh, Mohammadali Soleimani
;
Hu, Jian-Ping
;
Huan, Xia-Juan
;
Song, Shan-Shan
;
Tian, Chang-Qing
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2020/07/01
BET inhibitor
Cell proliferation
Apoptosis
Anti-cancer agent
Smart Tumor Microenvironment-Responsive Nanotheranostic Agent for Effective Cancer Therapy
期刊论文
ADVANCED FUNCTIONAL MATERIALS, 2020, 页码: 11
作者:
Guo, Shi-yan
;
Sun, Di
;
Ni, Da-long
;
Yu, Miao-rong
;
Qian, Kun
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  |  
浏览/下载:36/0
  |  
提交时间:2020/07/01
hypoxia relief
mesoporous calcium silicate
sequential functions
sustained drug release
synergetic effects
Application of multiple chemical and biological approaches for quality assessment of Carthamus tinctorius L. (safflower) by determining both the primary and secondary metabolites
期刊论文
PHYTOMEDICINE, 2019, 卷号: 58, 页码: 12
作者:
Lu, Jia-Xi
;
Zhanga, Chun-Xia
;
Hu, Ying
;
Zhang, Meng-Han
;
Wang, Ya-Nan
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2020/07/01
UHPLC/Q-Orbitrap MS
Quantitative H-1 NMR
Carthamus tinctorius
Primary metabolite
Secondary metabolite
Quality evaluation
Bioactive polyoxygenated cembranoids from a novel Hainan chemotype of the soft coral Sinularia flexibilis
期刊论文
Bioorganic & medicinal chemistry letters, 2019, 卷号: 29, 期号: 2, 页码: 185-188
作者:
Wu, Qihao
;
Li, Xu-Wen
;
Li, Heng
;
Yao, Li-Gong
;
Tang, Wei
收藏
  |  
浏览/下载:71/0
  |  
提交时间:2019/01/08
Discovery of a series of dihydroquinoxalin-2(1H)-ones as selective BET inhibitors from a dual PLK1-BRD4 inhibitor
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 137, 页码: 176-195
作者:
Hu, Jianping
;
Wang, Yingqing
;
Li, Yanlian
;
Xu, Lin
;
Cao, Danyan
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2019/01/08
BRD4 inhibitor
Kinase
BI-2536
Dihydroquinoxalin-2(1H)-one
Norisoboldine ameliorates DSS-induced ulcerative colitis in mice through induction of regulatory T cells in colons
期刊论文
International immunopharmacology, 2015, 卷号: 29, 期号: 2, 页码: 787-797
作者:
Lv, Qi
;
Qiao, Si-Miao
;
Xia, Ying
;
Shi, Can
;
Xia, Yu-Feng
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  |  
浏览/下载:8/0
  |  
提交时间:2019/01/08
Fragment-Based Drug Discovery of 2-Thiazolidinones as BRD4 Inhibitors: 2. Structure-Based Optimization
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2015, 卷号: 58, 期号: 3, 页码: 1281-1297
作者:
Zhao, Lele
;
Wang, Yingqing
;
Cao, Danyan
;
Chen, Tiantian
;
Wang, Qi
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2019/01/08
Epirubicin-Loaded Superparamagnetic Iron-Oxide Nanoparticles for Transdermal Delivery: Cancer Therapy by Circumventing the Skin Barrier
期刊论文
SMALL, 2015, 卷号: 11, 期号: 2, 页码: 239-247
作者:
Rao, Yue-feng
;
Chen, Wei
;
Liang, Xing-guang
;
Huang, Yong-zhuo
;
Miao, Jing
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2019/01/08
superparamagnetic materials
iron oxide
nanoparticles
drug delivery
epirubicin
cancer
biomedical applications
L-stepholidine blocks methamphetamine-induced locomotor sensitization in mice
会议论文
作者:
Ma, Bao Miao
;
Yue, Kai
;
Xing, Jun Qiao
;
Gong, Xiao Kang
;
Ru, Qin
收藏
  |  
浏览/下载:61/0
  |  
提交时间:2019/01/08
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