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科研机构
上海药物研究所 [30]
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期刊论文 [29]
会议论文 [1]
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2021 [2]
2020 [1]
2018 [1]
2017 [1]
2016 [6]
2015 [2]
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Discovery of potential small molecular SARS-CoV-2 entry blockers targeting the spike protein
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9
作者:
Wang, Lin
;
Wu, Yan
;
Yao, Sheng
;
Ge, Huan
;
Zhu, Ya
收藏
  |  
浏览/下载:86/0
  |  
提交时间:2021/11/04
SARS-CoV-2
natural products
virtual screening
spike protein
protein-protein interaction modulators
Antibodies Against Pseudomonas aeruginosa Alkaline Protease Directly Enhance Disruption of Neutrophil Extracellular Traps Mediated by This Enzyme
期刊论文
FRONTIERS IN IMMUNOLOGY, 2021, 卷号: 12, 页码: 16
作者:
Jing, Chendi
;
Liu, Chenghua
;
Liu, Yu
;
Feng, Ruli
;
Cao, Run
收藏
  |  
浏览/下载:68/0
  |  
提交时间:2021/05/24
Pseudomonas aeruginosa
alkaline protease
alkaline protease inhibitor
neutrophil extracellular traps
antibody-dependent enhancement
SARS-CoV-2 and Three Related Coronaviruses Utilize Multipke ACE2 Orthologs and Are Potently Blocked by an Improved ACE2-Ig
期刊论文
JOURNAL OF VIROLOGY, 2020, 卷号: 94, 期号: 22, 页码: 14
作者:
Li, Yujun
;
Wang, Haimin
;
Tang, Xiaojuan
;
Fang, Shisong
;
Ma, Danting
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2020/12/21
ACE2
ACE2-Ig
SARS-CoV-2
entry inhibitor
host range
Hydrogen-Bonded Organic Aromatic Frameworks for Ultralong Phosphorescence by Intralayer pi-pi Interactions
期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2018, 卷号: 57, 期号: 15, 页码: 4005-4009
作者:
Cai, Suzhi
;
Shi, Huifang
;
Zhang, Zaiyong
;
Wang, Xuan
;
Ma, Huili
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  |  
浏览/下载:82/0
  |  
提交时间:2019/01/08
hydrogen bonds
hydrogen-bonded organic frameworks
pi interactions
self-assembly
ultralong organic phosphorescence
Anti-amnesic effect of extract and alkaloid fraction from aerial parts of Peganum harmala on scopolamine-induced memory deficits in mice
期刊论文
Journal of ethnopharmacology, 2017, 卷号: 204, 页码: 95-106
作者:
Liu, Wei
;
Zhu, Yudan
;
Wang, Yongli
;
Qi, Shenglan
;
Wang, Yuwen
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  |  
浏览/下载:34/0
  |  
提交时间:2019/01/08
Functional human induced hepatocytes (hiHeps) with bile acid synthesis and transport capacities: A novel in vitro cholestatic model
期刊论文
Scientific Reports, 2016, 卷号: 6
作者:
Ni, Xuan
;
Gao, Yimeng
;
Wu, Zhitao
;
Ma, Leilei
;
Chen, Chen
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  |  
浏览/下载:48/0
  |  
提交时间:2019/01/08
Synthesis and cytotoxicity evaluation of 4 '-amino-4 '-dehydroxyloleandrin derivatives
期刊论文
FITOTERAPIA, 2016, 卷号: 113, 页码: 85-90
作者:
Chen, Hu
;
Lei, Min
;
Ma, Biao
;
Liu, Miao
;
Guo, Dean
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  |  
浏览/下载:64/0
  |  
提交时间:2019/01/08
Oleandrin
Antitumor agent
Natural product
Cytotoxicity
Structure-activity relationships (SARs)
Synthesis and biological evaluation of bufalin-3-yl nitrogen-containing-carbamate derivatives as anticancer agents
期刊论文
STEROIDS, 2016, 卷号: 108, 页码: 56-60
作者:
Lei, Min
;
Xiao, Zhiyong
;
Ma, Biao
;
Chen, Yijia
;
Liu, Miao
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  |  
浏览/下载:57/0
  |  
提交时间:2019/01/08
Cardiac glycosides
Bufalin (BF)
Natural product
Bufalin-3-yl carbamate
Cytotoxicity
Inhibition of hepatic cytochrome P450 enzymes and sodium/bile acid cotransporter exacerbates leflunomide-induced hepatotoxicity
期刊论文
ACTA PHARMACOLOGICA SINICA, 2016, 卷号: 37, 期号: 3, 页码: 415-424
作者:
Ma, Lei-lei
;
Wu, Zhi-tao
;
Wang, Le
;
Zhang, Xue-feng
;
Wang, Jing
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2019/01/08
leflunomide
hepatotoxicity
CYPs
teriflunomide
aminobenzotriazole
proadifen
NTCP
cholestasis
Improved survival of porcine acute liver failure by a bioartificial liver device implanted with induced human functional hepatocytes
期刊论文
CELL RESEARCH, 2016, 卷号: 26, 期号: 2, 页码: 206-216
作者:
Shi, Xiao-Lei
;
Gao, Yimeng
;
Yan, Yupeng
;
Ma, Hucheng
;
Sun, Lulu
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2019/01/08
acute liver failure
functional hepatocytes
bioartificial liver
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