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科研机构
上海药物研究所 [21]
内容类型
期刊论文 [21]
发表日期
2021 [1]
2020 [2]
2019 [1]
2013 [6]
2012 [1]
2010 [3]
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A 36-week multicenter, randomized, double-blind, placebo-controlled, parallel-group, phase 3 clinical trial of sodium oligomannate for mild-to-moderate Alzheimer’s dementia
期刊论文
Alzheimer's Research & Therapy, 2021, 卷号: 13, 期号: 1
作者:
Xiao,Shifu
;
Chan,Piu
;
Wang,Tao
;
Hong,Zhen
;
Wang,Shuzhen
收藏
  |  
浏览/下载:151/0
  |  
提交时间:2021/05/24
Sodium oligomannate
Efficacy
Safety
Alzheimer’s disease
Clinical trial
A phase II randomized trial of sodium oligomannate in Alzheimer's dementia
期刊论文
ALZHEIMERS RESEARCH & THERAPY, 2020, 卷号: 12, 期号: 1, 页码: 10
作者:
Wang, Tao
;
Kuang, Weihong
;
Chen, Wei
;
Xu, Wenwei
;
Zhang, Liming
收藏
  |  
浏览/下载:64/0
  |  
提交时间:2020/12/21
Sodium oligomannate
Efficacy
Safety
Alzheimer's disease
Clinical trial
A phase II randomized trial of sodium oligomannate in Alzheimer’s dementia
期刊论文
Alzheimer's Research & Therapy, 2020, 卷号: 12, 期号: 1
作者:
Wang,Tao
;
Kuang,Weihong
;
Chen,Wei
;
Xu,Wenwei
;
Zhang,Liming
收藏
  |  
浏览/下载:71/0
  |  
提交时间:2020/12/24
Sodium oligomannate
Efficacy
Safety
Alzheimer’s disease
Clinical trial
Small molecule IVQ, as a prodrug of gluconeogenesis inhibitor QVO, efficiently ameliorates glucose homeostasis in type 2 diabetic mice
期刊论文
ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 9, 页码: 1193-1204
作者:
Zhou, Ting-ting
;
Zhao, Tong
;
Ma, Fei
;
Zhang, Yi-nan
;
Jiang, Jing
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2020/07/01
type 2 diabetes mellitus
hepatic gluconeogenesis
AMPK signaling pathway
(E)-3-(2-(quinoline-4-yl)vinyl)-1H-indol-6-ol (QVO)
4-[2-(1H-indol-3-yl)vinyl]quinoline (IVQ)
prodrug
Metabolite identification of crude extract from Ganoderma lucidum in rats using ultra-performance liquid chromatography-quadrupole time-of-flight mass spectrometry
期刊论文
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2013, 卷号: 941, 页码: 90-99
作者:
Cheng, Chun-Ru
;
Yang, Min
;
Yu, Kate
;
Guan, Shu-Hong
;
Wu, Xiao-Hui
收藏
  |  
浏览/下载:60/0
  |  
提交时间:2019/01/08
Ganoderma lucidum
Ganoderic acid
Metabolism
Metabolite identification
UPLC/Q-TOF
Elution-extrusion Counter-current Chromatography Separation of Two New Benzyl Ester Glucosides and Three Other High-polarity Compounds from the Tubers of Pleione bulbocodioides
期刊论文
PHYTOCHEMICAL ANALYSIS, 2013, 卷号: 24, 期号: 6, 页码: 671-676
作者:
Wang, Yang
;
Guan, Shu-hong
;
Feng, Rui-hong
;
Zhang, Jing-xian
;
Li, Qing
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2019/01/08
Counter-current chromatography
high-polarity
benzyl ester glucosides
gastrodin
Pleione bulbocodioides
Phenanthrenes, 9,10-dihydrophenanthrenes, bibenzyls with their derivatives, and malate or tartrate benzyl ester glucosides from tubers of Cremastra appendiculata
期刊论文
PHYTOCHEMISTRY, 2013, 卷号: 94, 页码: 268-276
作者:
Wang, Yang
;
Guan, Shu-Hong
;
Meng, Yu-Hui
;
Zhang, Yi-Bei
;
Cheng, Chun-Ru
收藏
  |  
浏览/下载:55/0
  |  
提交时间:2019/01/08
Cremastra appendiculata
Orchidaceae
Bibenzyl
Phenanthrene
9,10-Dihydrophenanthrene
2,3,4,5-Tetrahydro-phenanthro[2,1-b]furan
Malate benzyl ester glucoside
Tartrate benzyl ester glucoside
Pharmacokinetics of ganoderic acid D and its main metabolite by liquid chromatography-tandem mass spectrometry
期刊论文
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2013, 卷号: 930, 页码: 1-6
作者:
Cheng, Chun-Ru
;
Yang, Min
;
Guan, Shu-Hong
;
Wu, Xiao-Hui
;
Pang, Xiao-Yan
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2019/01/08
Ganoderic acid D
Ganoderic acid B
LC/MS/MS
Nanoparticle
Pharmacokinetics
Triterpenoid
Simultaneous determination of 24 constituents in Cortex Lycii using high-performance liquid chromatography-triple quadrupole mass spectrometry
期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2013, 卷号: 77, 页码: 63-70
作者:
Zhang, Jing-Xian
;
Guan, Shu-Hong
;
Yang, Min
;
Feng, Rui-Hong
;
Wang, Yang
收藏
  |  
浏览/下载:52/0
  |  
提交时间:2019/01/08
HPLC-ESI-MS/MS
Cortex Lycii
Quantification
Cyclic peptides
Phenolic amides
Principal component analysis
Neolignanamides, Lignanamides, and Other Phenolic Compounds from the Root Bark of Lycium chinense
期刊论文
JOURNAL OF NATURAL PRODUCTS, 2013, 卷号: 76, 期号: 1, 页码: 51-58
作者:
Zhang, Jing-Xian
;
Guan, Shu-Hong
;
Feng, Rui-Hong
;
Wang, Yang
;
Wu, Zhi-Yuan
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2019/01/08
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