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Design and synthesis of Imidazo[1,2-b]pyridazine IRAK4 inhibitors for the treatment of mutant MYD88 L265P diffuse large B-cell lymphoma 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 190, 页码: 14
作者:  Chen, Yun;  Bai, Gang;  Ning, Yi;  Cai, Shi;  Zhang, Tao
收藏  |  浏览/下载:26/0  |  提交时间:2020/07/01
Structure-Based Design of 5-Methylpyrimidopyridone Derivatives as New Wild-Type Sparing Inhibitors of the Epidermal Growth Factor Receptor Triple Mutant (EGFR(L858R/T790M/C797S)) 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 15, 页码: 7302-7308
作者:  Shen, Jiayi;  Zhang, Tao;  Zhu, Su-Jie;  Sun, Min;  Tong, Linjiang
收藏  |  浏览/下载:30/0  |  提交时间:2020/07/01
Structure and dynamics of the active human parathyroid hormone receptor-1 期刊论文
SCIENCE, 2019, 卷号: 364, 期号: 6436, 页码: 148-+
作者:  Zhao, Li-Hua;  Ma, Shanshan;  Sutkeviciute, Ieva;  Shen, Dan-Dan;  Zhou, X. Edward
收藏  |  浏览/下载:12/0  |  提交时间:2020/07/01
Discovery of JND3229 as a New EGFR(C797S) Mutant Inhibitor with In Vivo Monodrug Efficacy 期刊论文
ACS MEDICINAL CHEMISTRY LETTERS, 2018, 卷号: 9, 期号: 11, 页码: 1123-1127
作者:  Lu, Xiaoyun;  Zhang, Tao;  Zhu, Su-Jie;  Xun, Qiuju;  Tong, Lingjiang
收藏  |  浏览/下载:111/0  |  提交时间:2019/01/08
Structure-based design and synthesis of 2,4-diaminopyrimidines as EGFR L858R/T790M selective inhibitors for NSCLC 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 140, 页码: 510-527
作者:  Chen, Lingfeng;  Fu, Weitao;  Feng, Chen;  Qu, Rong;  Tong, Linjiang
收藏  |  浏览/下载:57/0  |  提交时间:2019/01/08
Limonoids and Triterpenoids as 11 beta-HSD1 Inhibitors from Walsura robusta 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2016, 卷号: 79, 期号: 4, 页码: 899-906
作者:  Wang, Guo-Cai;  Yu, Jin-Hai;  Shen, Yu;  Leng, Ying;  Zhang, Hua
收藏  |  浏览/下载:18/0  |  提交时间:2019/01/08
Pharmacokinetics and metabolism study of isoboldine, a major bioactive component from Radix Linderae in male rats by UPLC-MS/MS 期刊论文
Journal of ethnopharmacology, 2015, 卷号: 171, 页码: 154-60
作者:  Li, Yu;  Zeng, Rong-jie;  Chen, Jian-zhong;  Wu, Yan-bin;  Chou, Gui-xin
收藏  |  浏览/下载:16/0  |  提交时间:2019/01/08
Diterpenes and lignans from Viburnum odoratissimum var. odoratissimum 期刊论文
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2015, 卷号: 17, 期号: 5, 页码: 475-481
作者:  Li, Feng-Jie;  Yu, Jin-Hai;  Wang, Guo-Cai;  Zhang, Hua;  Yue, Jian-Min
收藏  |  浏览/下载:14/0  |  提交时间:2019/01/08
A single, multi-faceted, enhanced strategy to quantify the chromatographically diverse constituents in the roots of Euphorbia kansui 期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2014, 卷号: 88, 页码: 321-330
作者:  Hou, Jin-Jun;  Wu, Wan-Ying;  Liang, Jian;  Yang, Zhou;  Long, Hua-Li
收藏  |  浏览/下载:17/0  |  提交时间:2019/01/08
Laevinoids A and B: Two Diterpenoids with an Unprecedented Backbone from Croton laevigatus 期刊论文
ORGANIC LETTERS, 2013, 卷号: 15, 期号: 18, 页码: 4880-4883
作者:  Wang, Guo-Cai;  Zhang, Hua;  Liu, Hong-Bing;  Yue, Jian-Min
收藏  |  浏览/下载:16/0  |  提交时间:2019/01/08


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