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浏览/检索结果: 共15条，第1-10条 帮助 限定条件 专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 LS-106, a novel EGFR inhibitor targeting C797S, exhibits antitumor activities both in vitro and in vivo 期刊论文 CANCER SCIENCE, 2021, 页码: 12 作者:  Liu, Yingqiang;  Lai, Mengzhen;  Li, Shan;  Wang, Yanan;  Feng, Fang 收藏  |  浏览/下载：63/0  |  提交时间：2022/01/18 C797S  epidermal growth factor receptor  fourth-generation EGFR TKI  non-small cell lung cancer  osimertinib resistance   Discovery of a novel third-generation EGFR inhibitor and identification of a potential combination strategy to overcome resistance (vol 19, 90, 2020) 期刊论文 MOLECULAR CANCER, 2021, 卷号: 20, 期号: 1, 页码: 1 作者:  Zhang, Tao;  Qu, Rong;  Chan, Shingpan;  Lai, Mengzhen;  Tong, Linjiang 收藏  |  浏览/下载：60/0  |  提交时间：2021/11/04 Rh(III)-catalyzed selective C7-H functionalization of indolines with 1,3-enynes enables access to six-membered 1,7-fused indolines 期刊论文 TETRAHEDRON LETTERS, 2021, 卷号: 72, 页码: 4 作者:  Shi, Yunkai;  Chen, Chao;  Yang, Yaxi;  Zhou, Bing 收藏  |  浏览/下载：14/0  |  提交时间：2021/08/17 C-H activation  1,7-Fused indoline  Enynes   Biomimetic codelivery overcomes osimertinib-resistant NSCLC and brain metastasis via macrophage-mediated innate immunity 期刊论文 JOURNAL OF CONTROLLED RELEASE, 2021, 卷号: 329, 页码: 1249-1261 作者:  Zhao, Pengfei;  Zhang, Jiaxin;  Wu, Aihua;  Zhang, Meng;  Zhao, Yuge 收藏  |  浏览/下载：109/0  |  提交时间：2021/05/24 Brain targeting delivery  Tumor-associated macrophage  Osimertinib resistance  Brain metastasis  Innate immunity  Combination therapy   PRMT1 is a novel molecular therapeutic target for clear cell renal cell carcinoma 期刊论文 THERANOSTICS, 2021, 卷号: 11, 期号: 11, 页码: 5387-5403 作者:  Wang, Jianfeng;  Wang, Chen;  Xu, Pan;  Li, Xiao;  Lu, Yongning 收藏  |  浏览/下载：131/0  |  提交时间：2021/05/24 clear cell renal cell carcinoma  protein arginine methyltransferase 1  therapeutic  lipocalin2 (LCN2)  sunitinib   Deep Learning Enhancing Kinome-Wide Polypharmacology Profiling: Model Construction and Experiment Validation 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 63, 期号: 16, 页码: 8723-8737 作者:  Li, Xutong;  Li, Zhaojun;  Wu, Xiaolong;  Xiong, Zhaoping;  Yang, Tianbiao 收藏  |  浏览/下载：29/0  |  提交时间：2020/12/21 Deep Learning Enhancing Kinome-Wide Polypharmacology Profiling: Model Construction and Experiment Validation 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 63, 期号: 16, 页码: 8723-8737 作者:  Li, Xutong;  Li, Zhaojun;  Wu, Xiaolong;  Xiong, Zhaoping;  Yang, Tianbiao 收藏  |  浏览/下载：23/0  |  提交时间：2020/12/21 Discovery of triazoloquinoxaline as novel STING agonists via structure-based virtual screening 期刊论文 BIOORGANIC CHEMISTRY, 2020, 卷号: 100, 页码: 8 作者:  Hou, Hui;  Yang, Ruirui;  Liu, Xiaohong;  Wu, Xiaolong;  Zhang, Sulin 收藏  |  浏览/下载：3/0  |  提交时间：2020/12/24 Discovery of a novel third-generation EGFR inhibitor and identification of a potential combination strategy to overcome resistance 期刊论文 MOLECULAR CANCER, 2020, 卷号: 19, 期号: 1, 页码: 15 作者:  Zhang, Tao;  Qu, Rong;  Chan, Shingpan;  Lai, Mengzhen;  Tong, Linjiang 收藏  |  浏览/下载：43/0  |  提交时间：2020/07/01 Non-small cell lung cancer (NSCLC)  EGFR T790M  Small-molecule inhibitor  Drug resistance  Ack1   Bioluminescence imaging of carbon monoxide in living cells based on a selective deiodination reaction 期刊论文 ANALYST, 2020, 卷号: 145, 期号: 2, 页码: 550-556 作者:  Wang, Anni;  Li, Xuewei;  Ju, Yong;  Chen, Dongying;  Lu, Jianzhong 收藏  |  浏览/下载：16/0  |  提交时间：2020/07/01