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CORC

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Discovery and Development of a Potent, Selective, and Orally Bioavailable CHK1 Inhibitor Candidate: 5-((4-((3-Amino-3-methylbutyl)amino)-5-(trifluoromethyl)pyrimidin-2-yl)amino)picolinonitrile 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 20, 页码: 15069-15090
作者:  Jin, Tingting;  Xu, Lei;  Wang, Peipei;  Hu, Xiaobei;  Zhang, Runyuan
收藏  |  浏览/下载：24/0  |  提交时间：2022/01/04
5-Aminonaphthalene derivatives as selective nonnucleoside nuclear receptor binding SET domain-protein 2 (NSD2) inhibitors for the treatment of multiple myeloma 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 222, 页码: 19
作者:  Wang, Shuni;  Yang, Hong;  Su, Mingbo;  Lian, Fulin;  Cong, Zhanqing
收藏  |  浏览/下载：82/0  |  提交时间：2021/11/04
Discovery of Potent and Selective CDK9 Degraders for Targeting Transcription Regulation in Triple-Negative Breast Cancer 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 19, 页码: 14822-14847
作者:  Wei, Dan;  Wang, Hanlin;  Zeng, Qinghe;  Wang, Wenjing;  Hao, Bingbing
收藏  |  浏览/下载：32/0  |  提交时间：2021/12/16
Rational Design and Development of Novel CDK9 Inhibitors for the Treatment of Acute Myeloid Leukemia 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 19, 页码: 14647-14663
作者:  Han, Xu;  Song, Ning;  Saidahmatov, Abdusaid;  Wang, Peipei;  Wang, Yong
收藏  |  浏览/下载：17/0  |  提交时间：2021/12/16
Synthesis of 5-Phenyl-1,3,4-thiadiazole Derivatives and Their Biochemical Evaluation against Src Homology 2 Domain-Containing Protein Tyrosine Phosphatase 1 (SHP1) 期刊论文
CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2021, 卷号: 41, 期号: 8, 页码: 3097-3105
作者:  Yu Lijie;  Feng Bo;  Wang Zhijia;  Gao Lixin;  Zhang Chun
收藏  |  浏览/下载：243/0  |  提交时间：2021/11/04
SARS-CoV-2 envelope protein causes acute respiratory distress syndrome (ARDS)-like pathological damages and constitutes an antiviral target 期刊论文
CELL RESEARCH, 2021, 页码: 14
作者:  Xia, Bingqing;  Shen, Xurui;  He, Yang;  Pan, Xiaoyan;  Liu, Feng-Liang
收藏  |  浏览/下载：80/0  |  提交时间：2021/08/17
Discovery of thalidomide-based PROTAC small molecules as the highly efficient SHP2 degraders 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 218, 页码: 14
作者:  Yang, Xiangbo;  Wang, Zhijia;  Pei, Yuan;  Song, Ning;  Xu, Lei
收藏  |  浏览/下载：40/0  |  提交时间：2021/08/17
Design, Synthesis, and Biological Evaluation of Orally Bioavailable CHK1 Inhibitors Active against Acute Myeloid Leukemia 期刊论文
CHEMMEDCHEM, 2021, 页码: 12
作者:  Jin, Tingting;  Wang, Peipei;  Long, Xiubing;  Jiang, Kailong;  Song, Pinrao
收藏  |  浏览/下载：134/0  |  提交时间：2021/05/24
Divalent tranylcypromine derivative as lysine-specific demethylase 1 inhibitor 期刊论文
MEDICINAL CHEMISTRY RESEARCH, 2021, 页码: 8
作者:  Sun, Yin;  Li, Na;  Su, Mingbo;  Wang, Xiaowen;  Zhao, Dongmei
收藏  |  浏览/下载：60/0  |  提交时间：2021/05/24
Design, synthesis and biological evaluation of thioether-containing lenalidomide and pomalidomide derivatives with anti-multiple myeloma activity 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 209, 页码: 13
作者:  Wang, Yuhong;  Mi, Tian;  Li, Yiming;  Kan, Weijuan;  Xu, Gaoya
收藏  |  浏览/下载：23/0  |  提交时间：2021/05/24

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