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Andrographolide Sulfonate Attenuates Acute Lung Injury by Reducing Expression of Myeloperoxidase and Neutrophil-Derived Proteases in Mice 期刊论文
FRONTIERS IN PHYSIOLOGY, 2018, 卷号: 9
作者:  Gao, Fei;  Liu, Xing;  Shen, Ziying;  Jia, Xiaohui;  He, Han
收藏  |  浏览/下载:51/0  |  提交时间:2019/01/08
Discovery of Potent and Orally Active Lipoprotein-Associated Phospholipase A(2) (Lp-PLA(2)) Inhibitors as a Potential Therapy for Diabetic Macular Edema 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2016, 卷号: 59, 期号: 6, 页码: 2674-2687
作者:  Chen, Xinde;  Wang, Kai;  Xu, Wenwei;  Ma, Quanxin;  Chen, Minli
收藏  |  浏览/下载:21/0  |  提交时间:2019/01/08
Discovery of a Novel Series of Imidazo[1,2-a]pyrimidine Derivatives as Potent and Orally Bioavailable Lipoprotein-Associated Phospholipase A(2) Inhibitors 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2015, 卷号: 58, 期号: 21, 页码: 8529-8541
作者:  Chen, Xinde;  Xu, Wenwei;  Wang, Kai;  Mo, Mingguang;  Zhang, Wei
收藏  |  浏览/下载:12/0  |  提交时间:2019/01/08
Discovery of pyrazole as C-terminus of selective BACE1 inhibitors 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2013, 卷号: 68, 页码: 270-283
作者:  Zou, Yiquan;  Xu, Lei;  Chen, Wuyan;  Zhu, Yiping;  Chen, Tiantian
收藏  |  浏览/下载:17/0  |  提交时间:2019/01/08
Triazole derivatives: A series of Darapladib analogues as orally active Lp-PLA(2) inhibitors 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2013, 卷号: 23, 期号: 10, 页码: 2897-2901
作者:  Wang, Kai;  Xu, Wenwei;  Zhang, Wei;  Mo, Mingguang;  Wang, Yiping
收藏  |  浏览/下载:19/0  |  提交时间:2019/01/08
Design and synthesis of imidazole and triazole derivatives as Lp-PLA(2) inhibitors and the unexpected discovery of highly potent quaternary ammonium salts 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2013, 卷号: 23, 期号: 5, 页码: 1187-1192
作者:  Wang, Kai;  Xu, Wenwei;  Liu, Yang;  Zhang, Wei;  Wang, Wenyi
收藏  |  浏览/下载:17/0  |  提交时间:2019/01/08
Design, synthesis and biological evaluation of novel dual inhibitors of acetylcholinesterase and beta-secretase 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2009, 卷号: 17, 期号: 4, 页码: 1600-1613
作者:  Zhu, Yiping;  Xiao, Kun;  Ma, Lanping;  Xiong, Bin;  Fu, Yan
收藏  |  浏览/下载:12/0  |  提交时间:2019/01/08
AD  AChE  BACE-1  Dual inhibitor  HE  HMC  HEA  
discoveryofpotentsecretasebace1inhibitorsbythesynthesisofisophthalamidecontaininghybrids 期刊论文
actapharmacologicasinica, 2009, 卷号: 030, 期号: 002, 页码: 259
作者:  Yiping ZHU;  Kun XIAO;  Haiping YU;  Lanping MA;  Bing XIONG
收藏  |  浏览/下载:17/0  |  提交时间:2020/07/01
Discovery of potent β-secretase (bace-1) inhibitors by the synthesis of isophthalamide-containing hybrids 期刊论文
中国药理学报:英文版, 2009, 卷号: 30.0, 期号: 002, 页码: 259
作者:  Yiping ZHU;  Kun XIAO;  Haiping YU;  Lanping MA;  Bing XIONG
收藏  |  浏览/下载:19/0  |  提交时间:2020/12/24
Heterologous expression of lipoprotein-associated phospholipase A(2) in different expression systems 期刊论文
PROTEIN EXPRESSION AND PURIFICATION, 2006, 卷号: 48, 期号: 2, 页码: 300-306
作者:  Zhang, Fujun;  Dong, Li;  Cai, Maojun;  Shen, Jingkang;  Wang, Yiping
收藏  |  浏览/下载:21/0  |  提交时间:2019/01/08


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