CORC

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CORC

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A structurally guided dissection-then-evolution strategy for ligand optimization of smoothened receptor 期刊论文
MEDCHEMCOMM, 2017, 卷号: 8, 期号: 6, 页码: 1332-1336
作者:  Ye, Lintao;  Ding, Kang;  Zhao, Fei;  Liu, Xiaoyan;  Wu, Yiran
收藏  |  浏览/下载：17/0  |  提交时间：2019/01/08
Structural optimization and biological evaluation of 1,5-disubstituted pyrazole-3-carboxamines as potent inhibitors of human 5-lipoxygenase 期刊论文
ACTA PHARMACEUTICA SINICA B, 2016, 卷号: 6, 期号: 1, 页码: 32-45
作者:  Zhou, Yu;  Liu, Jun;  Zheng, Mingyue;  Zheng, Shuli;  Jiang, Chunyi
收藏  |  浏览/下载：22/0  |  提交时间：2019/01/08
structuraloptimizationandbiologicalevaluationofl5disubstitutedpyrazole3carboxaminesaspotentinhibitorsofhuman5lipoxygenase 期刊论文
actapharmaceuticasinicab, 2016, 卷号: 6, 期号: 1, 页码: 32
作者:  Zhou Yu;  Liu Jun;  Zheng Mingyue;  Zheng Shuli;  Jiang Chunyi
收藏  |  浏览/下载：5/0  |  提交时间：2020/07/01
Structural optimization and biological evaluation of l,5-disubstituted pyrazole-3-carboxamines as potent inhibitors of human 5-lipoxygenase 期刊论文
Acta Pharmaceutica Sinica B, 2016, 卷号: 6, 期号: 1, 页码: 32
作者:  Zhou Yu;  Liu Jun;  Zheng Mingyue;  Zheng Shuli;  Jiang Chunyi
收藏  |  浏览/下载：20/0  |  提交时间：2020/12/24
Discovery and Mechanism Study of SIRT1 Activators that Promote the Deacetylation of Fluorophore-Labeled Substrate 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2013, 卷号: 56, 期号: 3, 页码: 761-780
作者:  Wu, Jiahui;  Zhang, Dengyou;  Chen, Lei;  Li, Jianneng;  Wang, Jianling
收藏  |  浏览/下载：21/0  |  提交时间：2019/01/08
Computational Screening for Active Compounds Targeting Protein Sequences: Methodology and Experimental Validation 期刊论文
JOURNAL OF CHEMICAL INFORMATION AND MODELING, 2011, 卷号: 51, 期号: 11, 页码: 2821-2828
作者:  Wang, Fei;  Liu, Dongxiang;  Wang, Heyao;  Luo, Cheng;  Zheng, Mingyue
收藏  |  浏览/下载：10/0  |  提交时间：2019/01/08
Structural Optimization and Biological Evaluation of Substituted Bisphenol A Derivatives as beta-Amyloid Peptide Aggregation Inhibitors 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2010, 卷号: 53, 期号: 15, 页码: 5449-5466
作者:  Zhou, Yu;  Jiang, Chunyi;  Zhang, Yaping;  Liang, Zhongjie;  Liu, Wenfeng
收藏  |  浏览/下载：13/0  |  提交时间：2019/01/08
An enzyme-linked immunosorbent assay to compare the affinity of chemical compounds for beta-amyloid peptide as a monomer 期刊论文
ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 2010, 卷号: 396, 期号: 5, 页码: 1745-1754
作者:  Jiang, Chunyi;  Feng, Yu;  Huang, Xiaotong;  Xu, Yechun;  Zhang, Yaping
收藏  |  浏览/下载：13/0  |  提交时间：2019/01/08
A conserved hydrophobic core at Bcl-x(L) mediates its structural stability and binding affinity with BH3-domain peptide of pro-apoptotic protein 期刊论文
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 2009, 卷号: 484, 期号: 1, 页码: 46-54
作者:  Feng, Yu;  Zhang, Liang;  Hu, Tianchen;  Shen, Xu;  Ding, Jianping
收藏  |  浏览/下载：12/0  |  提交时间：2019/01/08

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