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CORC

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G protein-coupled receptors: structure- and function-based drug discovery 期刊论文
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2021, 卷号: 6, 期号: 1, 页码: 27
作者:  Yang, Dehua;  Zhou, Qingtong;  Labroska, Viktorija;  Qin, Shanshan;  Darbalaei, Sanaz
收藏  |  浏览/下载：24/0  |  提交时间：2021/05/24
Targeted Proteomics Combined with Affinity Mass Spectrometry Analysis Reveals Antagonist E7 Acts As an Intracellular Covalent Ligand of Orphan Receptor GPR52 期刊论文
ACS CHEMICAL BIOLOGY, 2020, 卷号: 15, 期号: 12, 页码: 3275-3284
作者:  Ma, Mengna;  Guo, Shimeng;  Lin, Xi;  Li, Shanshan;  Wu, Yiran
收藏  |  浏览/下载：16/0  |  提交时间：2021/05/24
A Novel G Protein-Biased and Subtype-Selective Agonist for a G Protein-Coupled Receptor Discovered from Screening Herbal Extracts 期刊论文
ACS CENTRAL SCIENCE, 2020, 卷号: 6, 期号: 2, 页码: 213-225
作者:  Zhang, Bingjie;  Zhao, Simeng;  Yang, Dehua;  Wu, Yiran;  Xin, Ye
收藏  |  浏览/下载：38/0  |  提交时间：2020/07/01
Structural basis of ligand recognition and self-activation of orphan GPR52 期刊论文
NATURE, 2020, 页码: 21
作者:  Lin, Xi;  Li, Mingyue;  Wang, Niandong;  Wu, Yiran;  Luo, Zhipu
收藏  |  浏览/下载：197/0  |  提交时间：2020/07/01
Colocalization Strategy Unveils an Underside Binding Site in the Transmembrane Domain of Smoothened Receptor 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 21, 页码: 9983-9989
作者:  Zhou, Fang;  Ding, Kang;  Zhou, Yiqing;  Liu, Yang;  Liu, Xiaoyan
收藏  |  浏览/下载：31/0  |  提交时间：2020/07/01
Crystal structure of the Frizzled 4 receptor in a ligand-free state 期刊论文
NATURE, 2018, 卷号: 560, 期号: 7720, 页码: 666-+
作者:  Yang, Shifan;  Wu, Yiran;  Xu, Ting-Hai;  de Waal, Parker W.;  He, Yuanzheng
收藏  |  浏览/下载：84/0  |  提交时间：2019/01/08
High-throughput identification of G protein-coupled receptor modulators through affinity mass spectrometry screening 期刊论文
CHEMICAL SCIENCE, 2018, 卷号: 9, 期号: 12, 页码: 3192-3199
作者:  Qin, Shanshan;  Meng, Mengmeng;  Yang, Dehua;  Bai, Wenwen;  Lu, Yan
收藏  |  浏览/下载：44/0  |  提交时间：2019/01/08
Human GLP-1 receptor transmembrane domain structure in complex with allosteric modulators 期刊论文
NATURE, 2017, 卷号: 546, 期号: 7657, 页码: 312-+
作者:  Song, Gaojie;  Yang, Dehua;  Wang, Yuxia;  de Graaf, Chris;  Zhou, Qingtong
收藏  |  浏览/下载：33/0  |  提交时间：2019/01/08
A structurally guided dissection-then-evolution strategy for ligand optimization of smoothened receptor 期刊论文
MEDCHEMCOMM, 2017, 卷号: 8, 期号: 6, 页码: 1332-1336
作者:  Ye, Lintao;  Ding, Kang;  Zhao, Fei;  Liu, Xiaoyan;  Wu, Yiran
收藏  |  浏览/下载：17/0  |  提交时间：2019/01/08
Crystal structure of a multi-domain human smoothened receptor in complex with a super stabilizing ligand 期刊论文
NATURE COMMUNICATIONS, 2017, 卷号: 8
作者:  Zhang, Xianjun;  Zhao, Fei;  Wu, Yiran;  Yang, Jun;  Han, Gye Won
收藏  |  浏览/下载：23/0  |  提交时间：2019/01/08

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