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浏览/检索结果: 共5条，第1-5条 帮助 限定条件 专题：北京大学    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Discovery of 2-((3-Acrylamido-4-methylphenyl)amino)-N-(2-methyl5-(3,4,5-trimethoxyben zamido)phenyI)-4-(methylamino)pyrimidine-5-carboxamide (CHMFL-BMX-078) as a Highly Potent and Selective Type II Irreversible Bone Marrow Kinase in the X Chro 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2017 Liang, Xiaofei; Lv, Fengchao; Wang, Beilei; Yu, Kailin; Wu, Hong; Qi, Ziping; Jiang, Zongru; Chen, Cheng; Wang, Aoli; Miao, Weili; Wang, Wenchao; Hu, Zhenquan; Liu, Juan; Liu, Xiaochuan; Zhao, Zheng; Wang, Li; Zhang, Shanchuan; Ye, Zi; Wang, Chu; Ren, Tao; Wang, Yinsheng; Liu, Qingsong; Liu, Jing 收藏  |  浏览/下载：4/0  |  提交时间：2017/12/03 GROWTH-FACTOR RECEPTOR  TYROSINE KINASE  COVALENT  ETK/BMX  FAMILY  CELLS  GENE  BTK  ACTIVATION  EXPRESSION   Parameter uncertainty-based pattern identification and optimization for robust decision making on watershed load reduction 期刊论文 JOURNAL OF HYDROLOGY, 2017 Jiang, Qingsong; Su, Han; Liu, Yong; Zou, Rui; Ye, Rui; Guo, Huaicheng 收藏  |  浏览/下载：6/0  |  提交时间：2017/12/03 Parameter uncertainty  Pattern identification  Robustness  Decision preference  Hybrid clustering analysis  Lake Bali  K-MEANS  QUALITY MODEL  AUTOMATIC CALIBRATION  CLUSTERING-ALGORITHM  CLIMATE-CHANGE  MANAGEMENT  RELIABILITY  NETWORKS  SENSITIVITY  STORMWATER   Ibrutinib targets mutant-EGFR kinase with a distinct binding conformation 期刊论文 ONCOTARGET, 2016 Wang, Aoli; Yan, Xiao-E; Wu, Hong; Wang, Wenchao; Hu, Chen; Chen, Cheng; Zhao, Zheng; Zhao, Peng; Li, Xixiang; Wang, Li; Wang, Beilei; Ye, Zi; Wang, Jinhua; Wang, Chu; Zhang, Wei; Gray, Nathanael S.; Weisberg, Ellen L.; Chen, Liang; Liu, Jing; Yun, Cai-Hong; Liu, Qingsong 收藏  |  浏览/下载：2/0  |  提交时间：2017/12/04 Ibrutinib  EGFR kinase  DFG-in/c-Helix-out  inactive conformation  NSCLC  BRUTONS TYROSINE KINASE  MANTLE-CELL LYMPHOMA  CHRONIC LYMPHOCYTIC-LEUKEMIA  GROWTH-FACTOR RECEPTOR  INHIBITORS  BTK  SYSTEM  CRYSTALLOGRAPHY  ACTIVATION  RESISTANCE   Design, synthesis and photophysical properties of A-D-A-D-A small molecules for photovoltaic application 期刊论文 DYES AND PIGMENTS, 2015 Yan, Weibo; Zhang, Qian; Qin, Qingsong; Ye, Senyun; Lin, Yuanwei; Liu, Zhiwei; Bian, Zuqiang; Chen, Yongsheng; Huang, Chunhui 收藏  |  浏览/下载：8/0  |  提交时间：2017/12/03 Linear-conjugated small molecules  Acceptor-donor-acceptor-donor-acceptor  Hole mobility  Low bandgap  Solution processed  Organic solar cell  ORGANIC SOLAR-CELLS  PROCESSED SMALL-MOLECULE  BENZODITHIOPHENE UNIT  PHYSICAL-PROPERTIES  PERYLENE DIIMIDE  END-GROUPS  EFFICIENCY  ACCEPTOR  DONOR  SEMICONDUCTORS   Ibrutinib selectively and irreversibly targets EGFR (L858R, Del19) mutant but is moderately resistant to EGFR (T790M) mutant NSCLC Cells 期刊论文 ONCOTARGET, 2015 Wu, Hong; Wang, Aoli; Zhang, Wei; Wang, Beilei; Chen, Cheng; Wang, Wenchao; Hu, Chen; Ye, Zi; Zhao, Zheng; Wang, Li; Li, Xixiang; Yu, Kailin; Liu, Juan; Wu, Jiaxin; Yan, Xiao-E; Zhao, Peng; Wang, Jinhua; Wang, Chu; Weisberg, Ellen L.; Gray, Nathanael S.; Yun, Cai-Hong; Liu, Jing; Chen, Liang; Liu, Qingsong 收藏  |  浏览/下载：4/0  |  提交时间：2017/12/03 ibrutinib  NSCLC  EGFR mutation  drug resistance  drug combination  GROWTH-FACTOR RECEPTOR  BRUTONS TYROSINE KINASE  CHRONIC LYMPHOCYTIC-LEUKEMIA  LUNG-CANCER  ACQUIRED-RESISTANCE  INHIBITORS  BTK  MUTATION  GEFITINIB  LYMPHOMA