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CORC

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Discovery of novel 2,4-diarylaminopyrimidine derivatives as potent and selective epidermal growth factor receptor (EGFR) inhibitors against L858R/T790M resistance mutation 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 152
作者:  Yan, Qi;  Chen, Yuzhe;  Tang, Baiyou;  Xiao, Qiang;  Qu, Rong
收藏  |  浏览/下载：14/0  |  提交时间：2019/12/05
Design, synthesis and pharmacological evaluation of new acyl sulfonamides as potent and selective Bcl-2 inhibitors 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2018, 卷号: 26, 期号: 2
作者:  Liu, Xiaohua;  Zhang, Yu;  Huang, Wenjing;  Tan, Wenfu;  Zhang, Ao
收藏  |  浏览/下载：3/0  |  提交时间：2019/12/05
Development of high potent and selective Bcl-2 inhibitors bearing the structural elements of natural product artemisinin 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 159
作者:  Liu, Xiaohua;  Zhang, Yu;  Huang, Wenjing;  Luo, Jia;  Li, Yang
收藏  |  浏览/下载：4/0  |  提交时间：2019/12/05
Discovery of Novel Macrocyclic Hedgehog Pathway Inhibitors Acting by Suppressing the Gli-Mediated Transcription 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 60, 期号: 19
作者:  Liu, Gang;  Huang, Wenjing;  Wang, Juan;  Liu, Xiaohua;  Yang, Jun
收藏  |  浏览/下载：5/0  |  提交时间：2019/12/05
Crystal structure of a multi-domain human smoothened receptor in complex with a super stabilizing ligand 期刊论文
NATURE COMMUNICATIONS, 2017, 卷号: 8
作者:  Zhang, Xianjun;  Zhao, Fei;  Wu, Yiran;  Yang, Jun;  Han, Gye Won
收藏  |  浏览/下载：3/0  |  提交时间：2019/12/05
Design, synthesis, and biological evaluation of optimized phthalazine derivatives as hedgehog signaling pathway inhibitors 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 138
作者:  Lu, Xiuhong;  Peng, Yuanqiu;  Wang, Chenglin;  Yang, Jun;  Bao, Xiaolong
收藏  |  浏览/下载：3/0  |  提交时间：2019/12/05
Synthesis and evaluation of novel benzylphthalazine derivatives as hedgehog signaling pathway inhibitors 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2016, 卷号: 26, 期号: 13
作者:  Bao, Xiaolong;  Peng, Yuanqiu;  Lu, Xiuhong;  Yang, Jun;  Zhao, Weili
收藏  |  浏览/下载：10/0  |  提交时间：2019/12/05
Design, Synthesis, and Pharmacological Evaluation of 2-(2,5-Dimethyl-5,6,7,8-tetrahydroquinolin-8-yl)-N-aryl Propanamides as Novel Smoothened (Smo) Antagonists 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2016, 卷号: 59, 期号: 24
作者:  Liu, Gang;  Xue, Ding;  Yang, Jun;  Wan, Juan;  Liu, Xiaohua
收藏  |  浏览/下载：5/0  |  提交时间：2019/12/05
Solasonine, A Natural Glycoalkaloid Compound, Inhibits Gli-Mediated Transcriptional Activity 期刊论文
MOLECULES, 2016, 卷号: 21, 期号: 10
作者:  Yang, Jun;  Huang, Wenjing;  Tan, Wenfu
收藏  |  浏览/下载：1/0  |  提交时间：2019/12/05
AT-101 inhibits hedgehog pathway activity and cancer growth 期刊论文
CANCER CHEMOTHERAPY AND PHARMACOLOGY, 2015, 卷号: 76, 期号: 3
作者:  Wang, Juan;  Peng, Yuanqiu;  Liu, Yuan;  Yang, Jun;  Huang, Ming
收藏  |  浏览/下载：6/0  |  提交时间：2019/12/13

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