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科研机构
上海药物研究所 [12]
内容类型
期刊论文 [12]
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2021 [3]
2019 [2]
2017 [1]
2016 [1]
2015 [2]
2014 [2]
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内容类型:期刊论文
专题:上海药物研究所
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Structurally diverse diterpenoid alkaloids from the lateral roots of Aconitum carmichaelii Debx. and their anti-tumor activities based on in vitro systematic evaluation and network pharmacology analysis
期刊论文
RSC ADVANCES, 2021, 卷号: 11, 期号: 43, 页码: 26594-26606
作者:
Yu, Yang
;
Wu, Shifei
;
Zhang, Jianqing
;
Li, Jiayuan
;
Yao, Changliang
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2021/11/04
Systematic characterization of chemical constituents in Mahuang decoction by UHPLC tandem linear ion trap-Orbitrap mass spectrometry coupled with feature-based molecular networking
期刊论文
JOURNAL OF SEPARATION SCIENCE, 2021, 页码: 11
作者:
Chen, Ling
;
Yao, Changliang
;
Li, Jiayuan
;
Wang, Jing
;
Yao, Shuai
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2021/08/17
feature‐
based molecular networking
linear ion trap‐
Orbitrap
Mahuang decoction
traditional Chinese medicine
Recent advances in chemical analysis of licorice (Gan-Cao)
期刊论文
FITOTERAPIA, 2021, 卷号: 149, 页码: 12
作者:
Cheng, Mengzhen
;
Zhang, Jianqing
;
Yang, Lin
;
Shen, Shijie
;
Li, Ping
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2021/05/24
Glycyrrhiza uralensis
Glycyrrhiza glabra
Glycyrrhiza inflata
Gan-Cao
Qualitative and quantitative analysis
Biological sample
Intestinal and hepatic biotransformation of pyrrolizidine alkaloid N-oxides to toxic pyrrolizidine alkaloids
期刊论文
ARCHIVES OF TOXICOLOGY, 2019, 卷号: 93, 期号: 8, 页码: 2197-2209
作者:
Yang, Mengbi
;
Ma, Jiang
;
Ruan, Jianqing
;
Ye, Yang
;
Fu, Peter Pi-Cheng
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2020/07/01
Pyrrolizidine alkaloid N-oxides
Pyrrolizidine alkaloids
Pyrrolizidine alkaloid N-oxide toxicity
Biotransformation of pyrrolizidine alkaloid N-oxides
Microbiota biotransformation
Pyrrole-Hemoglobin Adducts, a More Feasible Potential Biomarker of Pyrrolizidine Alkaloid Exposure
期刊论文
CHEMICAL RESEARCH IN TOXICOLOGY, 2019, 卷号: 32, 期号: 6, 页码: 1027-1039
作者:
Ma, Jiang
;
Ruan, Jianqing
;
Chen, Xinmeng
;
Li, Dongping
;
Yao, Sheng
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2020/07/01
First evidence of pyrrolizidine alkaloid N-oxide-induced hepatic sinusoidal obstruction syndrome in humans
期刊论文
ARCHIVES OF TOXICOLOGY, 2017, 卷号: 91, 期号: 12, 页码: 3913-3925
作者:
Yang, Mengbi
;
Ruan, Jianqing
;
Gao, Hong
;
Li, Na
;
Ma, Jiang
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2019/01/08
Pyrrolizidine alkaloid N-oxide
Pyrrolizidine alkaloid
Hepatic sinusoidal obstruction syndrome
Pyrrole-protein adduct
Biotransformation
Toxicokinetic
Cytotoxicity of pyrrolizidine alkaloid in human hepatic parenchymal and sinusoidal endothelial cells: Firm evidence for the reactive metabolites mediated pyrrolizidine alkaloid-induced hepatotoxicity
期刊论文
Chemico-biological interactions, 2016, 卷号: 243, 页码: 119-26
作者:
Yang, Mengbi
;
Ruan, Jianqing
;
Fu, Peter P
;
Lin, Ge
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2019/01/08
Blood Pyrrole-Protein Adducts-A Biomarker of Pyrrolizidine Alkaloid-Induced Liver Injury in Humans
期刊论文
JOURNAL OF ENVIRONMENTAL SCIENCE AND HEALTH PART C-ENVIRONMENTAL CARCINOGENESIS & ECOTOXICOLOGY REVIEWS, 2015, 卷号: 33, 期号: 4, 页码: 404-421
作者:
Ruan, Jianqing
;
Gao, Hong
;
Li, Na
;
Xue, Junyi
;
Chen, Jie
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2019/01/08
hepatic sinusoidal obstruction syndrome
hepatotoxicity
pyrrolizidine alkaloids
pyrrole-protein adducts
Blood pyrrole-protein adducts as a diagnostic and prognostic index in pyrrolizidine alkaloid-hepatic sinusoidal obstruction syndrome
期刊论文
DRUG DESIGN DEVELOPMENT AND THERAPY, 2015, 卷号: 9, 页码: 4861-4868
作者:
Gao, Hong
;
Ruan, Jianqing Q.
;
Chen, Jie
;
Li, Na
;
Ke, Changqiang Q.
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2019/01/08
drug-induced liver injury
herb
blood protein adducts
prognostic marker
Metabolic Activation of Pyrrolizidine Alkaloids: Insights into the Structural and Enzymatic Basis
期刊论文
CHEMICAL RESEARCH IN TOXICOLOGY, 2014, 卷号: 27, 期号: 6, 页码: 1030-1039
作者:
Ruan, Jianqing
;
Yang, Mengbi
;
Fu, Peter
;
Ye, Yang
;
Lin, Ge
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2019/01/08
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