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Inhibition of Autophagy by a Small Molecule through Covalent Modification of the LC3 Protein 期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2021, 页码: 11
作者:  Fan, Shijie;  Yue, Liyan;  Wan, Wei;  Zhang, Yuanyuan;  Zhang, Bidong
收藏  |  浏览/下载:81/0  |  提交时间:2021/12/16
Activation pathway of a G protein-coupled receptor uncovers conformational intermediates as targets for allosteric drug design 期刊论文
NATURE COMMUNICATIONS, 2021, 卷号: 12, 期号: 1, 页码: 15
作者:  Lu, Shaoyong;  He, Xinheng;  Yang, Zhao;  Chai, Zongtao;  Zhou, Shuhua
收藏  |  浏览/下载:39/0  |  提交时间:2021/11/04
Discovery of novel ceramide analogs with favorable pharmacokinetic properties and combination with AKT inhibitor against colon cancer 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 215, 页码: 13
作者:  Gao, Feng;  Chen, Xiaoxu;  Lu, Junyan;  Hu, Shulei;  Xu, Hui
收藏  |  浏览/下载:46/0  |  提交时间:2021/05/24
A Sphingosine-1-Phosphate Modulator Ameliorates Polycystic Kidney Disease in Han:SPRD Rats 期刊论文
AMERICAN JOURNAL OF NEPHROLOGY, 2020, 卷号: 51, 期号: 1, 页码: 1-10
作者:  Li, Xin;  Wu, Ming;  Chen, Limin;  Lu, Junyan;  Li, Guo
收藏  |  浏览/下载:29/0  |  提交时间:2020/07/01
Targeting the N Terminus of eIF4AI for Inhibition of Its Catalytic Recycling 期刊论文
CELL CHEMICAL BIOLOGY, 2019, 卷号: 26, 期号: 10, 页码: 1417-+
作者:  Jiang, Chenxiao;  Tang, Yegen;  Ding, Lulu;  Tan, Renke;  Li, Xiaojing
收藏  |  浏览/下载:15/0  |  提交时间:2020/07/01
PI-273, a Substrate-Competitive, Specific Small-Molecule Inhibitor of PI4KII alpha, Inhibits the Growth of Breast Cancer Cells 期刊论文
CANCER RESEARCH, 2017, 卷号: 77, 期号: 22, 页码: 6253-6266
作者:  Li, Jiangmei;  Gao, Zhen;  Zhao, Dan;  Zhang, Lunfeng;  Qiao, Xinhua
收藏  |  浏览/下载:27/0  |  提交时间:2019/01/08
Inhibition of Eukaryotic Translation by the Antitumor Natural Product Agelastatin A 期刊论文
CELL CHEMICAL BIOLOGY, 2017, 卷号: 24, 期号: 5, 页码: 605-+
作者:  McClary, Brandon;  Zinshteyn, Boris;  Meyer, Melanie;  Jouanneau, Morgan;  Pellegrino, Simone
收藏  |  浏览/下载:12/0  |  提交时间:2019/01/08
Identification of novel EZH2 inhibitors through pharmacophore-based virtual screening and biological assays 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2016, 卷号: 26, 期号: 15, 页码: 3813-3817
作者:  Wu, Yunlong;  Hu, Junchi;  Ding, Hong;  Chen, Limin;  Zhang, Yuanyuan
收藏  |  浏览/下载:34/0  |  提交时间:2019/01/08
Identification of Novel Disruptor of Telomeric Silencing 1-like (DOT1L) Inhibitors through Structure-Based Virtual Screening and Biological Assays 期刊论文
JOURNAL OF CHEMICAL INFORMATION AND MODELING, 2016, 卷号: 56, 期号: 3, 页码: 527-534
作者:  Chen, Shijie;  Li, Linjuan;  Chen, Yantao;  Hu, Junchi;  Liu, Jingqiu
收藏  |  浏览/下载:21/0  |  提交时间:2019/01/08
A computational investigation on the substrate preference of ten-eleven-translocation 2 (TET2) 期刊论文
PHYSICAL CHEMISTRY CHEMICAL PHYSICS, 2016, 卷号: 18, 期号: 6, 页码: 4728-4738
作者:  Lu, Junyan;  Hu, Lulu;  Cheng, Jingdong;  Fang, Dong;  Wang, Chen
收藏  |  浏览/下载:25/0  |  提交时间:2019/01/08


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