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浏览/检索结果: 共15条，第1-10条 帮助 限定条件 发表日期：2021     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Rational Design and Development of Novel CDK9 Inhibitors for the Treatment of Acute Myeloid Leukemia 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 19, 页码: 14647-14663 作者:  Han, Xu;  Song, Ning;  Saidahmatov, Abdusaid;  Wang, Peipei;  Wang, Yong 收藏  |  浏览/下载：18/0  |  提交时间：2021/12/16 Disrupted intrinsic functional brain topology in patients with major depressive disorder 期刊论文 MOLECULAR PSYCHIATRY, 2021, 页码: 9 作者:  Yang, Hong;  Chen, Xiao;  Chen, Zuo-Bing;  Li, Le;  Li, Xue-Ying 收藏  |  浏览/下载：95/0  |  提交时间：2021/09/24 Initial years' neutron-induced cross-section measurements at the CSNS Back-n white neutron source * 期刊论文 CHINESE PHYSICS C, 2021, 卷号: 45, 期号: 6, 页码: 14 作者:  Tang, Jingyu;  Liu, Rong;  Zhang, Guohui;  Ruan, Xichao;  Wu, Xiaoguang 收藏  |  浏览/下载：70/0  |  提交时间：2021/12/09 white neutron beam  experimental spectrometers  nuclear data measurements  nuclides  data analysis   Development of Potent NEDD8-Activating Enzyme Inhibitors Bearing a Pyrimidotriazole Scaffold 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 9, 页码: 6161-6178 作者:  Xiong, Chaodong;  Zhou, Lina;  Tan, Jing;  Song, Shanshan;  Bao, Xubin 收藏  |  浏览/下载：35/0  |  提交时间：2021/08/17 Natural product 1,2,3,4,6-penta-O-galloyl-beta-D-glucopyranose is a reversible inhibitor of glyceraldehyde 3-phosphate dehydrogenase 期刊论文 ACTA PHARMACOLOGICA SINICA, 2021, 页码: 13 作者:  Li, Wen;  Liao, Li-ping;  Song, Ning;  Liu, Yan-jun;  Ding, Yi-luan 收藏  |  浏览/下载：83/0  |  提交时间：2021/06/11 glyceraldehyde 3-phosphate dehydrogenase  1,2,3,4,6-penta-O-galloyl-beta-D-glucopyranose  hydrogen deuterium exchange mass spectrometry  reversible inhibitor  glycolysis   Natural product 1,2,3,4,6-penta-O-galloyl-beta-D-glucopyranose is a reversible inhibitor of glyceraldehyde 3-phosphate dehydrogenase 期刊论文 ACTA PHARMACOLOGICA SINICA, 2021, 页码: 13 作者:  Li, Wen;  Liao, Li-ping;  Song, Ning;  Liu, Yan-jun;  Ding, Yi-luan 收藏  |  浏览/下载：82/0  |  提交时间：2021/06/11 glyceraldehyde 3-phosphate dehydrogenase  1,2,3,4,6-penta-O-galloyl-beta-D-glucopyranose  hydrogen deuterium exchange mass spectrometry  reversible inhibitor  glycolysis   Disrupted hemispheric connectivity specialization in patients with major depressive disorder: Evidence from the REST-meta-MDD Project 期刊论文 JOURNAL OF AFFECTIVE DISORDERS, 2021, 卷号: 284, 页码: 217-228 作者:  Ding, Yu-Dan;  Yang, Ru;  Yan, Chao-Gan;  Chen, Xiao;  Bai, Tong-Jian 收藏  |  浏览/下载：172/0  |  提交时间：2021/04/19 Major depressive disorder  hemispheric asymmetry  parameter of asymmetry  fMRI Abbreviations ACC, Anterior cingulate gyrus  DLPFC, Dorsolateral prefrontal cortex  DMN, Default mode network  DPARSF, Data Processing Assistant for Resting-State fMRI  DSM, Diagnosic and Statistical Manual of Mental Disorders  EEG, Electroencephalographic  FC, Functional connectivity  FDR, False discovery rate  FEDN, First-episode, drug-naive  FEF, Frontal eye fields  fMRI, Functional magnetic resonance imaging  HAMD, Hamilton Depression Rating Scale  HC, Healthy control  IFG, Inferior frontal gyrus  IPL, Inferior parietal lobule  IPS/SPL, Intraparietal sulcus/superior parietal lobule  LMM, Linear mixed model  MDD, Major depressive disorder  MFG, Middle frontal gyrus  MTG, Middle temporal gyrus  PAS, Parameter of asymmetry  PCC, Posterior cingulate cortex  PET, Positron emission tomography  ROIs, Regions of interest  rs-fMRI, Resting-state fMRI  rTMS, repetitive transcranial magnetic stimulation  STS, Superior temporal sulcus  VMHC, Voxel-mirrored homotopic connectivity   Discovery of MTR-106 as a highly potent G-quadruplex stabilizer for treating BRCA-deficient cancers 期刊论文 INVESTIGATIONAL NEW DRUGS, 2021, 页码: 9 作者:  Li, Meng-Zhu;  Meng, Tao;  Song, Shan-Shan;  Bao, Xu-Bin;  Ma, Lan-Ping 收藏  |  浏览/下载：69/0  |  提交时间：2021/05/24 G-quadruplex stabilizer  MTR-106  BRCA-deficiency  PARP inhibitor  DNA damage   Glycogen synthase kinase 3 beta inhibition synergizes with PARP inhibitors through the induction of homologous recombination deficiency in colorectal cancer 期刊论文 CELL DEATH & DISEASE, 2021, 卷号: 12, 期号: 2, 页码: 18 作者:  Zhang, Ning;  Tian, Yu-Nan;  Zhou, Li-Na;  Li, Meng-Zhu;  Chen, Hua-Dong 收藏  |  浏览/下载：22/0  |  提交时间：2021/05/24 Database Resources of the National Genomics Data Center, China National Center for Bioinformation in 2021 期刊论文 NUCLEIC ACIDS RESEARCH, 2021, 卷号: 49, 期号: D1, 页码: D18-D28 作者:  Xue, Yongbiao;  Bao, Yiming;  Zhang, Zhang;  Zhao, Wenming;  Xiao, Jingfa 收藏  |  浏览/下载：87/0  |  提交时间：2021/12/01