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浏览/检索结果: 共6条，第1-6条 帮助 限定条件 发表日期：2021    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Discovery of potential small molecular SARS-CoV-2 entry blockers targeting the spike protein 期刊论文 ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9 作者:  Wang, Lin;  Wu, Yan;  Yao, Sheng;  Ge, Huan;  Zhu, Ya 收藏  |  浏览/下载：91/0  |  提交时间：2021/11/04 SARS-CoV-2  natural products  virtual screening  spike protein  protein-protein interaction modulators   Alteration of twinfilin1 expression underlies opioid withdrawal-induced remodeling of actin cytoskeleton at synapses and formation of aversive memory 期刊论文 MOLECULAR PSYCHIATRY, 2021, 页码: 19 作者:  Wang, Yu-Jun;  Yu, Chuan;  Wu, Wei-Wei;  Ju, Yun-Yue;  Liu, Yao 收藏  |  浏览/下载：81/0  |  提交时间：2021/06/11 Twin drug design, synthesis and evaluation of diosgenin derivatives as multitargeted agents for the treatment of vascular dementia 期刊论文 BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 卷号: 37, 页码: 16 作者:  Yang, Gui-Xiang;  Sun, Jia-Min;  Zheng, Lu-Lu;  Zhang, Li;  Li, Jie 收藏  |  浏览/下载：72/0  |  提交时间：2021/06/11 Vascular dementia  Diosgenin  Antioxidant  Anti-cholinesterase  Multi-target-directed ligands   9,10-Anhydrodehydroartemisinin Attenuates Experimental Autoimmune Encephalomyelitis by Inhibiting Th1 and Th17 Cell Differentiation 期刊论文 INFLAMMATION, 2021, 页码: 10 作者:  Lv, Jie;  Zhuang, Wei;  Zhang, Yan;  Xie, Ling;  Xiang, Zhenglong 收藏  |  浏览/下载：29/0  |  提交时间：2021/05/24 9  10-Anhydrodehydroartemisinin  artemisinin  multiple sclerosis  Th1  Th17  experimental autoimmune encephalomyelitis   SAF-248, a novel PI3K delta-selective inhibitor, potently suppresses the growth of diffuse large B-cell lymphoma 期刊论文 ACTA PHARMACOLOGICA SINICA, 2021, 页码: 11 作者:  Zhang, Xi;  Duan, Yu-ting;  Wang, Yi;  Zhao, Xing-dong;  Sun, Yi-ming 收藏  |  浏览/下载：40/0  |  提交时间：2021/05/24 PI3Kδ  PI3K  AKT  mTOR  diffuse large B-cell lymphoma  resistance  combination therapy   Identification of methyl (5-(6-((4-(methylsulfonyl)piperazin-1-yl)methyl)-4-morpholinopyrrolo[2,1-f][1,2,4]triazin-2-yl)-4-(trifluoromethyl)pyridin-2-yl)carbamate (CYH33) as an orally bioavailable, highly potent, PI3K alpha inhibitor for the treatment of advanced solid tumors 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 209, 页码: 10 作者:  Xiang, Hao-Yue;  Wang, Xiang;  Chen, Yan-Hong;  Zhang, Xi;  Tan, Cun 收藏  |  浏览/下载：36/0  |  提交时间：2021/05/24 PI3K  Pyrrolo[2,1-f][1,2,4]triazine  Anti-cancer  Target therapy