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浏览/检索结果: 共11条，第1-10条 帮助 限定条件 发表日期：2021    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Ainsliadimer C, a disesquiterpenoid isolated from Ainsliaea macrocephala, ameliorates inflammatory responses in adipose tissue via Sirtuin 1-NLRP3 inflammasome axis 期刊论文 ACTA PHARMACOLOGICA SINICA, 2021, 页码: 13 作者:  Chen, Cheng;  Ren, Yong-mei;  Zhu, Jian-zhong;  Chen, Jia-li;  Feng, Zhe-ling 收藏  |  浏览/下载：56/0  |  提交时间：2022/01/04 Ainsliadimer C  interleukin-1 beta  macrophages  NLRP3 inflammasome  Sirtuin 1  adipose tissue inflammation  obesity  metabolic disorders  EX-527  dexamethasone   Rhodomeroterpene alleviates macrophage infiltration and the inflammatory response in renal tissue to improve acute kidney injury 期刊论文 FASEB JOURNAL, 2021, 卷号: 35, 期号: 11, 页码: 17 作者:  Wu, Yong-Mei;  Shi, Qing;  Zhu, Peng-Fei;  Ma, Hai-Jian;  Cui, Shi-Chao 收藏  |  浏览/下载：55/0  |  提交时间：2021/12/16 acute kidney injury  IKK/NF-kappa B  inflammation  macrophage  PI3K/PDK1/Akt  rhodomeroterpene   Rational Design and Development of Novel CDK9 Inhibitors for the Treatment of Acute Myeloid Leukemia 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 19, 页码: 14647-14663 作者:  Han, Xu;  Song, Ning;  Saidahmatov, Abdusaid;  Wang, Peipei;  Wang, Yong 收藏  |  浏览/下载：18/0  |  提交时间：2021/12/16 Structural insights into the activation of human calcium-sensing receptor 期刊论文 ELIFE, 2021, 卷号: 10, 页码: 24 作者:  Chen, Xiaochen;  Wang, Lu;  Cui, Qianqian;  Ding, Zhanyu;  Han, Li 收藏  |  浏览/下载：70/0  |  提交时间：2021/11/04 G-protein-coupled receptor  calcium-sensing receptor  cryo-electron microscopy  calcium ions  nanobody  CaSR  GPCR  cryo-EM  None   SARS-CoV-2 envelope protein causes acute respiratory distress syndrome (ARDS)-like pathological damages and constitutes an antiviral target 期刊论文 CELL RESEARCH, 2021, 页码: 14 作者:  Xia, Bingqing;  Shen, Xurui;  He, Yang;  Pan, Xiaoyan;  Liu, Feng-Liang 收藏  |  浏览/下载：83/0  |  提交时间：2021/08/17 A systematic strategy integrating solid-phase extraction, full scan range splitting, mass defect filter and precursor ion list for comprehensive metabolite profiling of Danqi Tongmai tablet in rats 期刊论文 JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2021, 卷号: 198, 页码: 9 作者:  Li, Zhen-wei;  Wei, Wen-long;  Li, Hao-jv;  Wu, Shi-fei;  Huang, Yong 收藏  |  浏览/下载：82/0  |  提交时间：2021/05/24 Metabolite profiling  Solid-phase extraction  Mass defect filter  Precursor ion list  Danqi Tongmai tablet   An enhanced strategy integrating offline superimposed two-dimensional separation with mass defect filter and diagnostic ion filter: Comprehensive characterization of steroid alkaloids in Fritillariae Pallidiflorae Bulbus as a case study 期刊论文 JOURNAL OF CHROMATOGRAPHY A, 2021, 卷号: 1643, 页码: 10 作者:  An, Ya-ling;  Wei, Wen-long;  Li, Hao-jv;  Li, Zhen-wei;  Yao, Chang-liang 收藏  |  浏览/下载：51/0  |  提交时间：2021/05/24 Mass defect filter  Diagnostic ion filter  Comprehensive characterization  Steroid alkaloids  Fritillariae Pallidiflorae Bulbus  Offline superimposed two-dimensional separation   Downregulation of c-Myc expression confers sensitivity to CHK1 inhibitors in hematologic malignancies 期刊论文 ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9 作者:  Jiang, Kai-long;  Tong, Le-xian;  Wang, Tao;  Wang, Han-lin;  Hu, Xiao-bei 收藏  |  浏览/下载：53/0  |  提交时间：2021/05/24 CHK1 inhibitors  PY34  drug sensitivity  c-Myc  hematologic malignancies   A 36-week multicenter, randomized, double-blind, placebo-controlled, parallel-group, phase 3 clinical trial of sodium oligomannate for mild-to-moderate Alzheimer’s dementia 期刊论文 Alzheimer's Research & Therapy, 2021, 卷号: 13, 期号: 1 作者:  Xiao,Shifu;  Chan,Piu;  Wang,Tao;  Hong,Zhen;  Wang,Shuzhen 收藏  |  浏览/下载：154/0  |  提交时间：2021/05/24 Sodium oligomannate  Efficacy  Safety  Alzheimer’s disease  Clinical trial   Structural insights into the human D1 and D2 dopamine receptor signaling complexes 期刊论文 CELL, 2021, 卷号: 184, 期号: 4, 页码: 931-+ 作者:  Zhuang, Youwen;  Xu, Peiyu;  Mao, Chunyou;  Wang, Lei;  Krumm, Brian 收藏  |  浏览/下载：22/0  |  提交时间：2021/05/24