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浏览/检索结果: 共23条，第1-10条 帮助 限定条件 发表日期：2021    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Genetically-engineered "all-in-one" vaccine platform for cancer immunotherapy 期刊论文 ACTA PHARMACEUTICA SINICA B, 2021, 卷号: 11, 期号: 11, 页码: 3622-3635 作者:  Wu, Aihua;  Chen, Yingzhi;  Wang, Hairui;  Chang, Ya;  Zhang, Meng 收藏  |  浏览/下载：27/0  |  提交时间：2022/01/18 Trichosanthin  Legumain  TRP2  Transcutaneous immunization  Adjuvant  Cancer vaccine  Protein engineering   Synthesis and bioactivity studies of covalent inhibitors derived from (-)-Chaetominine 期刊论文 JOURNAL OF MOLECULAR STRUCTURE, 2021, 卷号: 1241, 页码: 14 作者:  Zhou, Xian;  Feng, Xuexin;  Wang, Dachi;  Chen, Deheng;  Wu, Gaoxing 收藏  |  浏览/下载：86/0  |  提交时间：2021/08/17 Chaetominine  Cellular growth inhibition  Cancer cell line  Covalent warhead   Constitutive signal bias mediated by the human GHRHR splice variant 1 期刊论文 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2021, 卷号: 118, 期号: 40, 页码: 10 作者:  Cong, Zhaotong;  Zhou, Fulai;  Zhang, Chao;  Zou, Xinyu;  Zhang, Huibing 收藏  |  浏览/下载：27/0  |  提交时间：2021/12/01 class B1 GPCR  receptor bias  cancer  cell proliferation   PARP14 inhibits microglial activation via LPAR5 to promote post-stroke functional recovery 期刊论文 AUTOPHAGY, 2021, 卷号: 17, 期号: 10, 页码: 2905-2922 作者:  Tang, Ying;  Liu, Jinchang;  Wang, Yu;  Yang, Li;  Han, Bing 收藏  |  浏览/下载：46/0  |  提交时间：2022/01/04 Autophagy  functional recovery  ischemic stroke  lysophosphatidic acid receptor 5  microglial activation  poly (ADP-ribose) polymerase 14   Insights into agonist-elicited activation of the human glucose-dependent insulinotropic polypeptide receptor 期刊论文 BIOCHEMICAL PHARMACOLOGY, 2021, 卷号: 192, 页码: 16 作者:  Yuliantie, Elita;  van der Velden, Wijnand J. C.;  Labroska, Viktorija;  Dai, Antao;  Zhao, Fenghui 收藏  |  浏览/下载：44/0  |  提交时间：2021/11/04 Glucose-dependent insulinotropic polypeptide receptor  G protein-coupled receptor  GPCR structure-function relationship  ERK  cAMP  Arrestin   Molecular insights into differentiated ligand recognition of the human parathyroid hormone receptor 2 期刊论文 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2021, 卷号: 118, 期号: 32, 页码: 8 作者:  Wang, Xi;  Cheng, Xi;  Zhao, Lihua;  Wang, Yuzhe;  Ye, Chenyu 收藏  |  浏览/下载：25/0  |  提交时间：2021/11/04 parathyroid hormone receptor 2  cryo-electron microscopy  G protein-coupled receptor  ligand recognition  syndromic short stature   Activation pathway of a G protein-coupled receptor uncovers conformational intermediates as targets for allosteric drug design 期刊论文 NATURE COMMUNICATIONS, 2021, 卷号: 12, 期号: 1, 页码: 15 作者:  Lu, Shaoyong;  He, Xinheng;  Yang, Zhao;  Chai, Zongtao;  Zhou, Shuhua 收藏  |  浏览/下载：36/0  |  提交时间：2021/11/04 Structural insights into hormone recognition by the human glucose-dependent insulinotropic polypeptide receptor 期刊论文 ELIFE, 2021, 卷号: 10, 页码: 20 作者:  Zhao, Fenghui;  Zhang, Chao;  Zhou, Qingtong;  Hang, Kaini;  Zou, Xinyu 收藏  |  浏览/下载：36/0  |  提交时间：2021/08/17 Discovery of Novel Allosteric Modulators Targeting an Extra-Helical Binding Site of GLP-1R Using Structure- and Ligand-Based Virtual Screening 期刊论文 BIOMOLECULES, 2021, 卷号: 11, 期号: 7, 页码: 14 作者:  Zhou, Qingtong;  Guo, Wanjing;  Dai, Antao;  Cai, Xiaoqing;  Vass, Marton 收藏  |  浏览/下载：42/0  |  提交时间：2021/08/17 GLP-1R  virtual screening  allosteric modulator  drug discovery  molecular docking   Acyl-CoA oxidase ACOX-1 interacts with a peroxin PEX-5 to play roles in larval development of Haemonchus contortus 期刊论文 PLOS PATHOGENS, 2021, 卷号: 17, 期号: 7, 页码: 21 作者:  Shi, Hengzhi;  Huang, Xiaocui;  Chen, Xueqiu;  Yang, Yi;  Wang, Zhao 收藏  |  浏览/下载：33/0  |  提交时间：2021/11/04