QQ客服 官方微博 反馈留言

浏览/检索结果: 共5条，第1-5条 帮助 限定条件 发表日期：2021    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Discovery of Potent and Selective CDK9 Degraders for Targeting Transcription Regulation in Triple-Negative Breast Cancer 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 19, 页码: 14822-14847 作者:  Wei, Dan;  Wang, Hanlin;  Zeng, Qinghe;  Wang, Wenjing;  Hao, Bingbing 收藏  |  浏览/下载：31/0  |  提交时间：2021/12/16 Itraconazole and rifampicin, as CYP3A modulators but not P-gp modulators, affect the pharmacokinetics of almonertinib and active metabolite HAS-719 in healthy volunteers 期刊论文 ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9 作者:  Liu, Lu;  Li, Wei;  Yang, Le;  Guo, Zi-tao;  Xue, Hao 收藏  |  浏览/下载：78/0  |  提交时间：2021/08/17 almonertinib  itraconazole  rifampicin  drug metabolism  drug interaction  CYP3A  P-gp  pharmacokinetics   Natural product 1,2,3,4,6-penta-O-galloyl-beta-D-glucopyranose is a reversible inhibitor of glyceraldehyde 3-phosphate dehydrogenase 期刊论文 ACTA PHARMACOLOGICA SINICA, 2021, 页码: 13 作者:  Li, Wen;  Liao, Li-ping;  Song, Ning;  Liu, Yan-jun;  Ding, Yi-luan 收藏  |  浏览/下载：82/0  |  提交时间：2021/06/11 glyceraldehyde 3-phosphate dehydrogenase  1,2,3,4,6-penta-O-galloyl-beta-D-glucopyranose  hydrogen deuterium exchange mass spectrometry  reversible inhibitor  glycolysis   Natural product 1,2,3,4,6-penta-O-galloyl-beta-D-glucopyranose is a reversible inhibitor of glyceraldehyde 3-phosphate dehydrogenase 期刊论文 ACTA PHARMACOLOGICA SINICA, 2021, 页码: 13 作者:  Li, Wen;  Liao, Li-ping;  Song, Ning;  Liu, Yan-jun;  Ding, Yi-luan 收藏  |  浏览/下载：81/0  |  提交时间：2021/06/11 glyceraldehyde 3-phosphate dehydrogenase  1,2,3,4,6-penta-O-galloyl-beta-D-glucopyranose  hydrogen deuterium exchange mass spectrometry  reversible inhibitor  glycolysis   Downregulation of c-Myc expression confers sensitivity to CHK1 inhibitors in hematologic malignancies 期刊论文 ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9 作者:  Jiang, Kai-long;  Tong, Le-xian;  Wang, Tao;  Wang, Han-lin;  Hu, Xiao-bei 收藏  |  浏览/下载：52/0  |  提交时间：2021/05/24 CHK1 inhibitors  PY34  drug sensitivity  c-Myc  hematologic malignancies