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科研机构
上海药物研究所 [13]
内容类型
期刊论文 [13]
发表日期
2021 [13]
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发表日期:2021
专题:上海药物研究所
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Beshanzoides A-D, unprecedented cycloheptanone-containing polyketides from Penicillium commune P-4-1, an endophytic fungus of the endangered conifer Abies beshanzuensis
期刊论文
RSC ADVANCES, 2021, 卷号: 11, 期号: 63, 页码: 39781-39789
作者:
Chen, Hao-Wei
;
Jiang, Chun-Xiao
;
Li, Jiyang
;
Li, Na
;
Zang, Yi
收藏
  |  
浏览/下载:48/0
  |  
提交时间:2022/01/18
STING inhibitor ameliorates LPS-induced ALI by preventing vascular endothelial cells-mediated immune cells chemotaxis and adhesion
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 12
作者:
Wu, Bing
;
Xu, Meng-meng
;
Fan, Chen
;
Feng, Chun-lan
;
Lu, Qiu-kai
收藏
  |  
浏览/下载:59/0
  |  
提交时间:2022/01/18
acute lung injury
STING
vascular endothelial cells
inflammatory cytokines
chemokines
chemotaxis
Discovery of Potent and Selective CDK9 Degraders for Targeting Transcription Regulation in Triple-Negative Breast Cancer
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 19, 页码: 14822-14847
作者:
Wei, Dan
;
Wang, Hanlin
;
Zeng, Qinghe
;
Wang, Wenjing
;
Hao, Bingbing
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2021/12/16
NGPF2 triggers synaptic scaling up through ALK-LIMK-cofilin-mediated mechanisms
期刊论文
CELL REPORTS, 2021, 卷号: 36, 期号: 7, 页码: 20
作者:
Zhou, Zikai
;
He, Guiqin
;
Zhang, Xiaoyun
;
Lv, Xin
;
Zhang, Xiaolin
收藏
  |  
浏览/下载:67/0
  |  
提交时间:2021/11/04
Itraconazole and rifampicin, as CYP3A modulators but not P-gp modulators, affect the pharmacokinetics of almonertinib and active metabolite HAS-719 in healthy volunteers
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9
作者:
Liu, Lu
;
Li, Wei
;
Yang, Le
;
Guo, Zi-tao
;
Xue, Hao
收藏
  |  
浏览/下载:78/0
  |  
提交时间:2021/08/17
almonertinib
itraconazole
rifampicin
drug metabolism
drug interaction
CYP3A
P-gp
pharmacokinetics
The inhibitory effect of 225 frequently-used traditional Chinese medicines for CYP3A4 metabolic enzyme by isoform-specific probe
期刊论文
FITOTERAPIA, 2021, 卷号: 152, 页码: 5
作者:
Wei, Wenlong
;
Li, Zhenwei
;
Li, Hao-jv
;
An, Yaling
;
Qu, Hua
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2021/08/17
Inhibitory effect
Frequently-used traditional Chinese medicines
Isoform-specific probe
Diversity-oriented synthesis of cembranoid derivatives as potential anti-inflammatory agents
期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 111, 页码: 8
作者:
Zhang, Cong
;
Li, Heng
;
Liu, Jin
;
Liu, Moting
;
Zhang, Hao
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2021/08/17
Marine natural product
Cembranoid
Anti-inflammation
molecular docking
structuremodification
Structure Activity Relationship
Chemical profiling of Huashi Baidu prescription, an effective anti-COVID-19 TCM formula, by UPLC-Q-TOF/MS
期刊论文
CHINESE JOURNAL OF NATURAL MEDICINES, 2021, 卷号: 19, 期号: 6, 页码: 473-480
作者:
Wei Wen-Long
;
Wu Shi-Fei
;
Li Hao-Jv
;
Li Zhen-Wei
;
Qu Hua
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2021/08/17
Huashi Baidu prescription
Corona virus disease 2019
Characterization of chemical constituents
ELISA
A systematic strategy integrating solid-phase extraction, full scan range splitting, mass defect filter and precursor ion list for comprehensive metabolite profiling of Danqi Tongmai tablet in rats
期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2021, 卷号: 198, 页码: 9
作者:
Li, Zhen-wei
;
Wei, Wen-long
;
Li, Hao-jv
;
Wu, Shi-fei
;
Huang, Yong
收藏
  |  
浏览/下载:81/0
  |  
提交时间:2021/05/24
Metabolite profiling
Solid-phase extraction
Mass defect filter
Precursor ion list
Danqi Tongmai tablet
Rh-Catalyzed cascade C-H activation/C-C cleavage/cyclization of carboxylic acids with cyclopropanols
期刊论文
CHEMICAL COMMUNICATIONS, 2021, 页码: 4
作者:
Wang, Siqi
;
Miao, Erfei
;
Wang, Hao
;
Song, Bichao
;
Huang, Wei
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2021/08/17
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