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浏览/检索结果: 共14条，第1-10条 帮助 限定条件 发表日期：2021    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Distal mutation V486M disrupts the catalytic activity of DPP4 by affecting the flap of the propeller domain 期刊论文 ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9 作者:  Li, Teng-teng;  Peng, Cheng;  Wang, Ji-qiu;  Xu, Zhi-jian;  Su, Ming-bo 收藏  |  浏览/下载：44/0  |  提交时间：2022/01/18 DPP4  distal mutation  enzymatic activity  molecular dynamics simulation  structure-function mechanism   Impurity Identification and Scale-Up of a Novel Glycopeptide Antibiotic 期刊论文 ORGANIC PROCESS RESEARCH & DEVELOPMENT, 2021, 卷号: 25, 期号: 11, 页码: 2390-2402 作者:  Jiao, Shang;  Guan, Dongliang;  Xu, Lili;  Liu, Bo;  Shi, Weiwei 收藏  |  浏览/下载：19/0  |  提交时间：2022/01/18 glycopeptide antibiotics  impurity  analytical method  process optimization and development   Discovery of chiral N-2 '-aryletheryl-1 '-alkoxy-ethyl substituted arylisoquinolones with anti-inflammatory activity from the nucleophilic addition reactions of the thiophenols and oxazolinium 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 222, 页码: 11 作者:  Li, Bo;  Li, Heng;  Zhu, Zhengdan;  Xiang, Caigui;  Xu, Zhijian 收藏  |  浏览/下载：105/0  |  提交时间：2021/11/04 Anti-inflammatory activity  TNF alpha  ER beta  IBD Arylisoquinolones   An Atom-Economic Inverse Solid-Phase Peptide Synthesis Using Bn or BcM Esters of Amino Acids 期刊论文 ORGANIC LETTERS, 2021, 卷号: 23, 期号: 19, 页码: 7571-7574 作者:  Li, Jian;  Zhu, Yue;  Liu, Bo;  Tang, Feng;  Zheng, Xing 收藏  |  浏览/下载：11/0  |  提交时间：2021/12/01 Quassinoids with Inhibitory Activities against Plant Fungal Pathogens from Picrasma javanica 期刊论文 JOURNAL OF NATURAL PRODUCTS, 2021, 卷号: 84, 期号: 8, 页码: 2111-2120 作者:  Chen, Jian-Jun;  Bai, Wei;  Lu, Yu-Bo;  Feng, Zi-Yun;  Gao, Kun 收藏  |  浏览/下载：33/0  |  提交时间：2021/11/04 Competitive CatSper Activators of Progesterone from Rhynchosia volubilis 期刊论文 PLANTA MEDICA, 2021, 页码: 10 作者:  Xiang, Jin;  Kang, Hang;  Li, Hong-Gang;  Shi, Yu-Long;  Zhang, Ya-Li 收藏  |  浏览/下载：44/0  |  提交时间：2021/11/04 Leguminosae  Rhynchosia volubilis  CatSper  prenylated isoflavonoids  rhynchones A - E   Pharmacodynamic, pharmacokinetic, and phase 1a study of bisthianostat, a novel histone deacetylase inhibitor, for the treatment of relapsed or refractory multiple myeloma 期刊论文 ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9 作者:  Zhou, Yu-bo;  Zhang, Yang-ming;  Huang, Hong-hui;  Shen, Li-jing;  Han, Xiao-feng 收藏  |  浏览/下载：98/0  |  提交时间：2021/11/04 multiple myeloma  HDAC inhibitor  bisthianostat  pharmacodynamics  pharmacokinetics  phase 1a clinical trial  antitumor drug   Graphene nanoribbon-based supramolecular ensembles with dual-receptor targeting function for targeted photothermal tumor therapy 期刊论文 CHEMICAL SCIENCE, 2021, 页码: 9 作者:  Dou, Wei-Tao;  Xu, Fugui;  Xu, Chen-Xi;  Gao, Jie;  Ru, Hong-Bo 收藏  |  浏览/下载：81/0  |  提交时间：2021/08/17 GPR160 is a potential biomarker associated with prostate cancer 期刊论文 SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2021, 卷号: 6, 期号: 1, 页码: 3 作者:  Guo, Wanjing;  Zhang, Junyu;  Zhou, Yan;  Zhou, Caihong;  Yang, Yunjie 收藏  |  浏览/下载：16/0  |  提交时间：2021/08/17 Anti-DLBCL efficacy of DCZ0825 in vitro and in vivo: involvement of the PI3K-AKT-mTOR/JNK pathway 期刊论文 ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2021, 卷号: 53, 期号: 5, 页码: 575-583 作者:  Hu, Ke;  Li, Bo;  Ma, Ruye;  Yi, Hongfei;  Xu, Zhijian 收藏  |  浏览/下载：70/0  |  提交时间：2021/06/11 caspase  cell proliferation  cell cycle arrest  diffuse large B-cell lymphoma  PI3K-AKT-mTOR/JNK pathway